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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
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Abt-263  Sorafenib  Combination Therapy  Cancer  
Effects of CO-RM2 on LPS-induced vascular cell adhesion molecule-1 expression and leukocyte adhesion in human rheumatoid synovial fibroblasts 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
Authors:  Pei-Ling Chi;  Yu-Chen Chuang;  Yu-Wen Chen;  Chih-Chung Lin;  Li-Der Hsiao;  Chuen-Mao Yang
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Carbon Monoxide  Lipopolysaccharide  Vcam-1  Leukocyte Adhesion  
Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 6
Authors:  Wang, Xue-Quan;  Chen, Xue-Bing;  Ye, Ping-Ting;  Yang, Zhi-Xin;  Bai, Meng-Jiao;  Duan, Su-Yue;  Li, Yan;  Yang, Xiao-Dong
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3-Benzylcoumarin  Imidazolium salts  Biological evaluation  Cytotoxic activity  Structure-activity relationships  
The Chromosome-Based Rubber Tree Genome Provides New Insights into Spurge Genome Evolution and Rubber Biosynthesis 期刊论文
MOLECULAR PLANT, 2020, 卷号: 13, 期号: 2, 页码: 336-350
Authors:  Liu, Jin;  Shi, Cong;  Shi, Cheng-Cheng;  Li, Wei;  Zhang, Qun-Jie;  Zhang, Yun;  Li, Kui;  Lu, Hui-Fang;  Shi, Chao;  Zhu, Si-Tao;  Xiao, Zai-Yun;  Nan, Hong;  Yue, Yao;  Zhu, Xun-Ge;  Wu, Yu;  Hong, Xiao-Ning;  Fan, Guang-Yi;  Tong, Yan;  Zhang, Dan;  Mao, Chang-Li;  Liu, Yun-Long;  Hao, Shi-Jie;  Liu, Wei-Qing;  Lv, Mei-Qi;  Zhang, Hai-Bin;  Liu, Yuan;  Hu-tang, Ge-Ran;  Wang, Jin-Peng;  Wang, Jia-Hao;  Sun, Ying-Huai;  Ni, Shu-Bang;  Chen, Wen-Bin;  Zhang, Xing-Cai;  Jiao, Yuan-Nian;  Eichler, Evan E.;  Li, Guo-Hua;  Liu, Xin;  Gao, Li-Zhi
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rubber tree  rubber biosynthesis  chromosome evolution  whole-genome duplication  domestication  
Catalyzed Synthesis of 3-hydroxy-indol-2-one Derivatives as a Novel Phosphodiesterases 10 Inhibitor 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 卷号: 126, 页码: 33-34
Authors:  Wu, Ya;  Li, Hao;  Yan, Jiao;  Cai, Qing;  Huang, Shengxiong;  Tang, Ying;  Ji, Yue;  Hao, Xiaojiang;  Chen, Gang
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The hornwort genome and early land plant evolution 期刊论文
NATURE PLANTS, 2020, 卷号: 6, 期号: 2, 页码: 107-118
Authors:  Zhang, Jian;  Fu, Xin-Xing;  Li, Rui-Qi;  Zhao, Xiang;  Liu, Yang;  Li, Ming-He;  Zwaenepoel, Arthur;  Ma, Hong;  Goffinet, Bernard;  Guan, Yan-Long;  Xue, Jia-Yu;  Liao, Yi-Ying;  Wang, Qing-Feng;  Wang, Qing-Hua;  Wang, Jie-Yu;  Zhang, Guo Qiang;  Wang, Zhi-Wen;  Jia, Yu;  Wang, Mei-Zhi;  Dong, Shan-Shan;  Yang, Jian-Fen;  Jiao, Yuan-Nian;  Guo, Ya-Long;  Kong, Hong-Zhi;  Lu, An-Ming;  Yang, Huan-Ming;  Zhang, Shou-Zhou;  Van de Peer, Yves;  Liu, Zhong-Jian;  Chen, Zhi-Duan
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Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10
Authors:  Li, Penghua;  He, Haiqing;  Zhang, Yunqin;  Yang, Rui;  Xu, Lili;  Chen, Zixi;  Huang, Yingying;  Bao, Limei;  Xiao, Guozhi
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Metabolomics reveals metabolite changes of patients with pulmonary arterial hypertension in China 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2020, 页码: 13
Authors:  Chen, Chenyang;  Luo, Fei;  Wu, Panyun;  Huang, Yiyuan;  Das, Avash;  Chen, Shenglan;  Chen, Jingyuan;  Hu, Xinqun;  Li, Fei;  Fang, Zhenfei;  Zhou, Shenhua
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lipid metabolism  metabolomics  pulmonary arterial hypertension  
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
Authors:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
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Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Aromatization of natural products by a specialized detoxification enzyme 期刊论文
NATURE CHEMICAL BIOLOGY, 2020, 卷号: 16, 期号: 3, 页码: 11
Authors:  Huang, Jin-Quan;  Fang, Xin;  Tian, Xiu;  Chen, Ping;  Lin, Jia-Ling;  Guo, Xiao-Xiang;  Li, Jian-Xu;  Fan, Zhen;  Song, Wei-Meng;  Chen, Fang-Yan;  Ahati, Ruzha;  Wang, Ling-Jian;  Zhao, Qing;  Martin, Cathie;  Chen, Xiao-Ya
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