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Steroidal alkaloid with unprecedented triheterocyclic architecture 期刊论文
CHEMICAL COMMUNICATIONS, 2023, 卷号: 59, 期号: 3, 页码: 326-329
作者:  Zhou,Zhong-Shun;  Zhao,Yun-Li;  Hu,Bin-Yuan;  Wang,Bei;  Liu,Ya-Ping;  Zhu,Yan-Yan;  He,Ying-Jie;  Wang,Zhao-Jie;  Dai,Zhi;  Zhao,Li-Xing;  Luo,Xiao-Dong
浏览  |  Adobe PDF(975Kb)  |  收藏  |  浏览/下载：65/12  |  提交时间：2024/07/22
MALIC-ACID  SKELETON  
Dimeric benzylisoquinoline alkaloids from Thalictrum delavayi and their biological activities 期刊论文
FITOTERAPIA, 2023, 卷号: 164, 页码: 105356
作者:  Jin,Qiong;  Qin,Xu-Jie;  Dai,Zhi;  Zhao,Yun;  Zhu,Yan-Yan;  Chen,Shan-Shan;  Liu,Ya-Ping;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1861Kb)  |  收藏  |  浏览/下载：38/11  |  提交时间：2024/07/25
Thalictrum delavayi  Ranunculaceae  Bisbenzylisoquinoline alkaloids  Cytotoxicities  Immunosuppressive effects  CYCLOARTANE GLYCOSIDES  APORPHINE  LEAVES  PLANTS  
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:  Zhao,Qi;  Dai,Man-Yun;  Huang,Ruo-Yue;  Duan,Jing-Yi;  Zhang,Ting;  Bao,Wei-Min;  Zhang,Jing-Yi;  Gui,Shao-Qiang;  Xia,Shu-Min;  Dai,Cong-Ting;  Tang,Ying-Mei;  Gonzalez,Frank J. J.;  Li,Fei
浏览  |  Adobe PDF(5393Kb)  |  收藏  |  浏览/下载：87/15  |  提交时间：2024/05/09
FATTY LIVER-DISEASE  INDUCED CHOLESTASIS  STELLATE CELLS  PROBIOTICS  PROTECTS  INFLAMMATION  APOPTOSIS  OBESITY  AXIS  
雷公藤制剂对消化系统的毒性机理研究 学位论文
: 中国科学院大学, 2022
作者:  代曼云
Adobe PDF(10574Kb)  |  收藏  |  浏览/下载：18/0  |  提交时间：2024/05/14
代谢组学，雷公藤，药源性肝损伤，消化性溃疡，FXR，ET-1， 肠道血管屏障  Metabolomics, Tripterygium wilfordii, Drug-induced liver injury, peptic ulcer disease, FXR, ET-1, intestinal vascular barrier.  
Bioactivity Ingredients of Chaenomeles speciosa against Microbes: Characterization by LC-MS and Activity Evaluation 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 16, 页码: 4686-4696
作者:  Wang,Zhao-Jie;  Jin,Dan-Ni;  Zhou,Ying;  Sang,Xu-Yan;  Zhu,Yan-Yan;  He,Ying-Jie;  Xie,Tian-Zhen;  Dai,Zhi;  Zhao,Yun-Li;  Luo,Xiao-Dong
收藏  |  浏览/下载：131/0  |  提交时间：2022/04/02
antimicrobial  Chaenomeles speciosa  LC-MS  metabolomics  LUNG INFLAMMATION  ANTIOXIDANT  FRUITS  POLYSACCHARIDE  
Polyamine metabolism links gut microbiota and testicular dysfunction 期刊论文
MICROBIOME, 2021, 卷号: 9, 期号: 1, 页码: 224
作者:  Zhao,Qi;  Huang,Jian-Feng;  Cheng,Yan;  Dai,Man-Yun;  Zhu,Wei-Feng;  Yang,Xiu-Wei;  Gonzalez,Frank J.;  Li,Fei
收藏  |  浏览/下载：98/0  |  提交时间：2022/04/02
Testicular dysfunction  Gut microbiota  Polyamine metabolism  Metabolomics  SMALL-MOLECULE INHIBITOR  ORNITHINE-DECARBOXYLASE  TRIPTOLIDE  SPERMINE  ACTIVATION  DISRUPTION  MECHANISMS  EXPRESSION  APOPTOSIS  TRANSPORT  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
作者:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2120Kb)  |  收藏  |  浏览/下载：287/54  |  提交时间：2022/04/02
Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 卷号: 44, 期号: 11, 页码: 2189-2205
作者:  Wang,Yi-Kun;  Zhou,Zi-Meng;  Dai,Man-Yun;  Ma,Xiao-Fang;  Xiao,Xue-Rong;  Zhang,Shou-Wen;  Liu,Hong-Ning;  Li,Fei
浏览  |  Adobe PDF(2083Kb)  |  收藏  |  浏览/下载：149/44  |  提交时间：2022/04/02
Fructus Aurantii  quality markers  metabolomics  serum pharmacochemistry  ultra high performance liquid chromatography  SERUM PHARMACOCHEMISTRY  RAT PLASMA  IDENTIFICATION  METABOLITES  IMMATURUS  COMPONENTS  EXTRACT  NEOHESPERIDIN  FINGERPRINT  NARINGIN  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
浏览  |  Adobe PDF(2010Kb)  |  收藏  |  浏览/下载：177/19  |  提交时间：2022/04/02
Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
Youngia hangii (Asteraceae, Crepidinae), a new species from Hubei, China 期刊论文
PHYTOKEYS, 2021, 期号: 182, 页码: 27-38
作者:  Liu,Qun;  Huang,Gui-Yun;  Zhang,Dai-Gui;  Zhang,Jian-Wen;  Deng,Tao;  Li,Zhi-Min
浏览  |  Adobe PDF(3796Kb)  |  收藏  |  浏览/下载：71/23  |  提交时间：2022/04/02
Crepidinae  Hubei  molecular phylogeny  morphology  new species  Youngia  POLLEN MORPHOLOGY  TRIBE CICHORIEAE  SICHUAN  GENERA  ROSACEAE