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Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
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PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE  
Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020
作者:  Li, Xue;  Kong, Lingmei;  Yang, Qihong;  Duan, Aizhu;  Ju, Xiaoman;  Cai, Bicheng;  Chen, Lin;  An, Tao;  Li, Yan
浏览  |  Adobe PDF(2381Kb)  |  收藏  |  浏览/下载:191/64  |  提交时间:2021/01/05
RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling 期刊论文
DEVELOPMENT, 2020
作者:  Ma, Pengcheng;  An, Tao;  Zhu, Liang;  Zhang, Longlong;  Wang, Huishan;  Ren, Biyu;  Sun, Bin;  Zhou, Xia;  Li, Yan;  Mao, Bingyu
浏览  |  Adobe PDF(1986Kb)  |  收藏  |  浏览/下载:158/45  |  提交时间:2021/01/05
Discovery of isopenicin A, a meroterpenoid as a novel inhibitor of tubulin polymerization 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020
作者:  Chen, Lin;  Fan, Dong-Mei;  Tang, Jian-Wei;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Puno, Pema-Tenzin;  Li, Yan
浏览  |  Adobe PDF(1132Kb)  |  收藏  |  浏览/下载:325/69  |  提交时间:2021/01/05
Star-PAP regulates tumor protein D52 through modulating miR-449a/34a in breast cancer 期刊论文
BIOLOGY OPEN, 2019, 卷号: 8, 期号: 11, 页码: 9
作者:  Duan, Aizhu;  Kong, Lingmei;  An, Tao;  Zhou, Hongyu;  Yu, Chunlei;  Li, Yan
浏览  |  Adobe PDF(2302Kb)  |  收藏  |  浏览/下载:374/71  |  提交时间:2020/03/02
Star-PAP  TPD52  miR-449a  miR-34a  Breast cancer  
Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin 期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 8, 页码: 1122-+
作者:  Zhu, Huifang;  Wang, Bin;  Kong, Lingmei;  An, Tao;  Li, Gentao;  Zhou, Hongyu;  Gong, Liang;  Zhao, Zhangxun;  Gong, Yaxiao;  Sun, Handong;  Puno, Pematenzin;  Li, Yan
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B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells 期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 18, 页码: 3371-3386
作者:  Zhou, Hongyu;  Yu, Chunlei;  Kong, Lingmei;  Xu, Xiaoliang;  Yan, Juming;  Li, Yingchao;  An, Tao;  Gong, Liang;  Gong, Yaxiao;  Zhu, Huifang;  Zhang, Hongbin;  Yang, Xiaodong;  Li, Yan
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Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
浏览  |  Adobe PDF(3189Kb)  |  收藏  |  浏览/下载:235/43  |  提交时间:2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Aurovertin B sensitizes colorectal cancer cells to NK cell recognition and lysis 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 503, 期号: 4, 页码: 3057-3063
作者:  Zhu, Huifang;  Wang, Fei;  Ju, Xiaoman;  Kong, Lingmei;  An, Tao;  Zhao, Zhangxun;  Liu, Jikai;  Li, Yan
收藏  |  浏览/下载:464/0  |  提交时间:2018/10/22
Aurovertin B  Cytotoxicity  Immunotherapy  NK cell  NKG2D ligands  
USP7 作为结直肠肿瘤治疗靶点的研究 学位论文
: 中国科学院大学, 2017
作者:  安涛
Adobe PDF(4516Kb)  |  收藏  |  浏览/下载:124/6  |  提交时间:2019/06/14