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Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1175-1184
作者:  Chen,Duo-Zhi;  Fan,Shi-Rui;  Yang,Bi-Juan;  Yao,Huo-Chun;  Wang,Yi-Ting;  Cai,Jie-Yun;  Jing,Chen-Xu;  Pan,Zi-Hao;  Luo,Miao;  Yuze,Yan-Qiu;  Liu,Guang-Jin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(8772Kb)  |  收藏  |  浏览/下载：88/20  |  提交时间：2022/04/02
PROTEIN  CORONAVIRUSES  SARS  PARTICLES  INSIGHTS  HSC70  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
Adobe PDF(3665Kb)  |  收藏  |  浏览/下载：68/9  |  提交时间：2022/04/02
Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis 期刊论文
PHYTOMEDICINE, 2020
作者:  Wang Yu-Ling;  Wu Wei;  Su Yong-Nan;  Ai Zhi-Peng;  Mou Han-Chuan;  Wan Luo-Sheng;  Luo Ying;  Qiu Ming-Hua;  Zhang Ji-Hong
Adobe PDF(7972Kb)  |  收藏  |  浏览/下载：128/33  |  提交时间：2021/01/05
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：312/37  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
一种HCV抑制剂中间体9-羟基-6-氧-4-甲基菲啶的全合成 期刊论文
云南民族大学学报(自然科学版), 2016, 期号: 6, 页码: 499-502
作者:  杨碧娟;  刘广锦;  郭晶晶;  景晨旭;  陈铎之;  郝小江
Adobe PDF(223Kb)  |  收藏  |  浏览/下载：394/96  |  提交时间：2016/12/19
全合成  9-羟基-6-氧-4-甲基菲啶  钯催化烷基-烷基  N-芳基一步偶联  
Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2016, 卷号: 79, 期号: 1, 页码: 180-188
作者:  Chen, Duo-Zhi;  Jing, Chen-Xu;  Cai, Jie-Yun;  Wu, Ji-Bo;  Wang, Sheng;  Yin, Jun -Lin;  Li, Xiao-Nian;  Li, Lin;  Hao, Xiao-Jiang
Adobe PDF(3043Kb)  |  收藏  |  浏览/下载：310/73  |  提交时间：2016/06/27
Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Chen,Duozhi;  Cai,Jieyun;  Cheng,Junjun;  Jing,Chenxu;  Yin,Junlin;  Jiang,Jiandong;  Peng,Zonggen;  Hao,Xiaojiang
Adobe PDF(833Kb)  |  收藏  |  浏览/下载：210/77  |  提交时间：2016/01/19
Physiological and Proteomic Adaptation of the Alpine Grass Stipa purpurea to a Drought Gradient 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 2, 页码: e0117475
作者:  Yang, Yunqiang;  Dong, Chao;  Yang, Shihai;  Li, Xiong;  Sun, Xudong;  Yang, Yongping;  Sun,XD (reprint author),Chinese Acad Sci,Kunming Inst Bot,Key Lab Plant Div & Biogeog East Asia,Kunming,Peoples R China.;  sunxudong@mail.kib.ac.cn;  yangyp@mail.kib.ac.cn
Adobe PDF(6656Kb)  |  收藏  |  浏览/下载：241/52  |  提交时间：2015/06/29
2015年中科院昆明植物研究所年报 其他
2015-01-01
作者:  KIB
Adobe PDF(40116Kb)  |  收藏  |  浏览/下载：139/10  |  提交时间：2017/08/17
Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2015, 卷号: 7, 期号: 5, 页码: 561-570
作者:  Chen, Duozhi;  Cai, Jieyun;  Yin, Junlin;  Jiang, Jiandong;  Jing, Chenxu;  Zhu, Yanping;  Cheng, Junjun;  Di, Yingtong;  Zhang, Yu;  Cao, Mingming;  Li, Shunlin;  Peng, Zonggen;  Hao, Xiaojiang;  Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  haoxj@mail.kib.ac.cn
Adobe PDF(1560Kb)  |  收藏  |  浏览/下载：291/54  |  提交时间：2015/07/20