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Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating [4+2] cycloaddition and target differentiation of enantiomers 期刊论文
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 4
作者:  He, Tao-Bin;  Yan, Bing-Chao;  Zhou, Yuan-Fei;  Sang, Yue-Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Wang, Chu;  Xue, Xiao-Song;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(3322Kb)  |  收藏  |  浏览/下载：39/5  |  提交时间：2024/05/09
DIELS-ALDER REACTION  BIOMIMETIC SYNTHESES  EFFICIENT ACCESS  DEHYDROGENATION  CYCLOHEXANONES  BIOSYNTHESIS  CONVERSION  OXIDATION  DYNAMICS  PHENOLS  
Cytochalasans from the Endophytic Fungus Phomopsis sp. shj2 and Their Antimigratory Activities 期刊论文
JOURNAL OF FUNGI, 2022, 卷号: 8, 期号: 5, 页码: 543
作者:  Yan, Bing-Chao;  Wang, Wei-Guang;  Kong, Ling-Mei;  Tang, Jian-Wei;  Du, Xue;  Li, Yan;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1464Kb)  |  收藏  |  浏览/下载：37/8  |  提交时间：2024/04/30
endophytic fungus  Phomopsis  cytochalasan  antimigratory activity  DERIVATIVES  
Elucidation of the Structure of Pseudorubriflordilactone B by Chemical Synthesis 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020
作者:  Yang, Peng;  Li, Jian;  Sun, Li;  Yao, Ming;  Zhang, Xiang;  Xiao, Wei-Lie;  Wang, Jian-Hua;  Tian, Ping;  Sun, Han-Dong;  Puno, Pema-Tenzin;  Li, Ang
浏览  |  Adobe PDF(2437Kb)  |  收藏  |  浏览/下载：196/49  |  提交时间：2021/01/05
(+)- and (-)-Alternarilactone A: Enantiomers with a Diepoxy-Cage-like Scaffold from an Endophytic Alternaria sp. 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 4, 页码: 735-740
作者:  Tang, Jian-Wei;  Xu, Hou-Chao;  Wang, Wei-Guang;  Hu, Kun;  Zhou, Yuan-Fei;  Chen, Rong;  Li, Xiao-Nian;  Du, Xue;  Sun, Han-Dong;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1213Kb)  |  收藏  |  浏览/下载：305/36  |  提交时间：2019/06/24
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：310/67  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 3, 页码: 771-775
作者:  Tang, Jian-Wei;  Kong, Ling-Mei;  Zu, Wen-Yu;  Hu, Kun;  Li, Xiao-Nian;  Yan, Bing-Chao;  Wang, Wei-Guang;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(2044Kb)  |  收藏  |  浏览/下载：277/33  |  提交时间：2019/03/18
Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 16
作者:  Hu, Jing;  Li, Xingren;  Tian, Weifeng;  Lu, Yanting;  Xu, Yuhui;  Wang, Fang;  Qin, Wanying;  Ma, Xiuli;  Puno, Pema-Tenzin;  Xiong, Wenyong
浏览  |  Adobe PDF(3093Kb)  |  收藏  |  浏览/下载：341/23  |  提交时间：2019/03/18
adenanthin  adipogenesis  reactive oxygen species  obesity  3T3-L1  
Rabdocoestin B exhibits antitumor activity by inducing G2/M phase arrest and apoptosis in esophageal squamous cell carcinoma 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2018, 卷号: 81, 期号: 3, 页码: 469-481
作者:  Wang, Jingnan;  Zhang, Zhirong;  Che, Yun;  Yuan, Zuyang;  Lu, Zhiliang;  Li, Yuan;  Wan, Jun;  Sun, Handong;  Chen, Zhaoli;  Pu, Jianxin;  He, Jie
收藏  |  浏览/下载：300/0  |  提交时间：2018/05/08
Rabdocoestin b  G2/m Phase Arrest  Apoptosis  Cytotoxicity  Esophageal Squamous Cell Carcinoma  
7 alpha,20-Epoxy-ent-kaurane Diterpenoids from the Aerial Parts of Isodon pharicus 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 1, 页码: 106-116
作者:  Hu, Zheng-Xi;  Liu, Miao;  Wang, Wei-Guang;  Li, Xiao-Nian;  Hu, Kun;  Li, Xing-Ren;  Du, Xue;  Zhang, Yong-Hui;  Puno, Pema-Tenzin;  Sun, Han-Dong
收藏  |  浏览/下载：327/0  |  提交时间：2018/05/08
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
收藏  |  浏览/下载：219/0  |  提交时间：2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC