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Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：225/45  |  提交时间：2020/03/26
Canescones A-E: aromatic polyketide dimers with PTP1B inhibitory activity from Penicillium canescens 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 18, 页码: 3274-3281
作者:  Zang, Yi;  Gong, Yi-Hua;  Li, Xu-Wen;  Li, Xiao-Nian;  Liu, Jun-Jun;  Chen, Chun-Mei;  Zhou, Yuan;  Gu, Liang-Hu;  Luo, Zeng-Wei;  Wang, Jian-Ping;  Sun, Wei-Guang;  Zhu, Hu-Cheng;  Zhang, Yong-Hui
浏览  |  Adobe PDF(2538Kb)  |  收藏  |  浏览/下载：208/48  |  提交时间：2019/10/28
Cytotoxic phenolic constituents from Hypericum japonicum 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 33-40
作者:  Zhu, Wei;  Qiu, Jie;  Zeng, Yan-Rong;  Yi, Ping;  Lou, Hua-Yong;  Jian, Jun-You;  Zuo, Ming-Xing;  Duan, Lian;  Gu, Wei;  Huang, Lie-Jun;  Li, Yan-Mei;  Yuan, Chun-Mao;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(902Kb)  |  收藏  |  浏览/下载：420/189  |  提交时间：2019/09/10
Hypericum japonicum thunb. (Hypericaceae)  Phenolic compounds  Xanthone and flavonoid derivatives  Cytotoxic activities  Structure-activity relationship  
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：250/72  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3136Kb)  |  收藏  |  浏览/下载：186/61  |  提交时间：2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1101Kb)  |  收藏  |  浏览/下载：269/110  |  提交时间：2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Metabolic Activation of Myristicin and Its Role in Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 15, 页码: 4328-4336
作者:  Zhu, Xu;  Wang, Yi-Kun;  Yang, Xiao-Nan;  Xiao, Xue-Rong;  Zhang, Ting;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Li, Fei
浏览  |  Adobe PDF(4316Kb)  |  收藏  |  浏览/下载：237/43  |  提交时间：2019/05/24
myristicin  1 '-hydroxymyristicin  metabolic activation  metabolomics  
Premnafulvol A: A Diterpenoid with a 6/5/7/3-Fused Tetracyclic Core and Its Biosynthetically Related Analogues from Premna fulva 期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 19, 页码: 6314-6317
作者:  Pu, De-Bing;  Du, Bao-Wen;  Chen, Wen;  Gao, Jun-Bo;  Hu, Kun;  Shi, Nan;  Li, Yi-Ming;  Zhang, Xing-Jie;  Zhang, Rui-Han;  Li, Xiao-Nian;  Zhang, Hong-Bin;  Wang, Fei;  Xiao, Wei-Lie
收藏  |  浏览/下载：184/0  |  提交时间：2018/11/12
Effects of indole alkaloids from leaf of &ITAlstonia scholaris&IT on post-infectious cough in mice 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 218, 页码: 69-75
作者:  Zhao, Yun-Li;  Yang, Zi-Feng;  Shang, Jian-Hua;  Huang, Wan-Yi;  Wang, Bei;  Wei, Xin;  Khan, Afsar;  Yuan, Zhi-Wei;  Liu, Ya-Ping;  Wang, Yi-Fen;  Wang, Xin-Hua;  Luo, Xiao-Dong
收藏  |  浏览/下载：204/0  |  提交时间：2018/05/08
Leaf Of Alstonia Scholaris  Indole Alkaloids  Scholaricine  19-epischolaricine  Vallesamine  Picrinine  Post-infectious Cough  
Antimicrobial indole alkaloids with adductive C-9 aromatic unit from Gelsemium elegans 期刊论文
TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 21, 页码: 2066-2070
作者:  Wei, Xin;  Yang, Jing;  Ma, Hong-Xia;  Ding, Cai-Feng;  Yu, Hao-Fei;  Zhao, Yun-Li;  Liu, Ya-Ping;  Khan, Afsar;  Wang, Yi-Fen;  Yang, Zi-Feng;  Huang, Wan-Yi;  Wang, Xin-Hua;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1063Kb)  |  收藏  |  浏览/下载：255/71  |  提交时间：2018/07/02
Gelsemium Elegans  Indole Alkaloids  Antimicrobial Activities