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Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：224/45  |  提交时间：2020/03/26
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3136Kb)  |  收藏  |  浏览/下载：186/61  |  提交时间：2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1101Kb)  |  收藏  |  浏览/下载：263/110  |  提交时间：2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Metabolic Activation of Myristicin and Its Role in Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 15, 页码: 4328-4336
作者:  Zhu, Xu;  Wang, Yi-Kun;  Yang, Xiao-Nan;  Xiao, Xue-Rong;  Zhang, Ting;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Li, Fei
浏览  |  Adobe PDF(4316Kb)  |  收藏  |  浏览/下载：236/43  |  提交时间：2019/05/24
myristicin  1 '-hydroxymyristicin  metabolic activation  metabolomics  
The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 977-989
作者:  Yi, Shou-pu;  Kong, Qing-hong;  Li, Yu-lei;  Pan, Chen-ling;  Yu, Jie;  Cui, Ben-qiang;  Wang, Ying-fei;  Wang, Guan-lin;  Zhou, Pei-lan;  Wang, Li-li;  Gong, Ze-hui;  Su, Rui-bin;  Shen, Yue-hai;  Yu, Gang;  Chang, Kwen-jen
浏览  |  Adobe PDF(854Kb)  |  收藏  |  浏览/下载：357/71  |  提交时间：2017/08/29
Opioid Receptor  Mixed Agonist  Dpi-125  Analgesia  Respiratory Depression  Addiction  
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:  Yang, Na;  Sun, Run-Bin;  Chen, Xing-Long;  Zhen, Le;  Ge, Chun;  Zhao, Yu-Qing;  He, Jun;  Geng, Jian-Liang;  Guo, Jia-Hua;  Yu, Xiao-Yi;  Fei, Fei;  Feng, Si-Qi;  Zhu, Xuan-Xuan;  Wang, Hong-Bo;  Fu, Feng-Hua;  Aa, Ji-Ye;  Wang, Guang-Ji
浏览  |  Adobe PDF(4661Kb)  |  收藏  |  浏览/下载：267/88  |  提交时间：2017/05/19
Hyperglycemia  Glucose-lowering Effect  Berberine  Berberrubine  Glucuronide  Alpha-glycosidase  Hfd-induced Hyperglycemia Model Of C57bl/6 Mice  Human Normal Liver Cell Line L-o2  Pharmacokinetics  
Potential effects of climate change on geographic distribution of the Tertiary relict tree species Davidia involucrata in China 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 43822
作者:  Tang,Cindy Q.;  Dong,Yi-Fei;  Herrando-Moraira,Sonia;  Matsui,Tetsuya;  Ohashi,Haruka;  He,Long-Yuan;  Nakao,Katsuhiro;  Tanaka,Nobuyuki;  Tomita,Mizuki;  Li,Xiao-Shuang;  Yan,Hai-Zhong;  Peng,Ming-Chun;  Hu,Jun;  Yang,Ruo-Han;  Li,Wang-Jun;  Yan,Kai;  Hou,Xiuli;  Zhang,Zhi-Ying;  Lopez-Pujol,Jordi
浏览  |  Adobe PDF(5229Kb)  |  收藏  |  浏览/下载：215/39  |  提交时间：2017/10/23
Last Glacial Maximum  Western North-america  Quaternary Climate  Extinction Risk  Change Threats  Europe  Phylogeography  Populations  Responses  Habitat  
Plasiatine, an Unprecedented Indole-Phenylpropanoid Hybrid from Plantago asiatica as a Potent Activator of the Nonreceptor Protein Tyrosine Phosphatase Shp2 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: 1, 页码: 24945
作者:  Gao, Zhong-Hua;  Shi, Yi-Ming;  Qiang, Zhe;  Wang, Xia;  Shang, Shan-Zhai;  Yang, Yan;  Du, Bao-Wen;  Peng, Hui-Pan;  Ji, Xu;  Li, Honglin;  Wang, Fei;  Xiao, Wei-Lie
浏览  |  Adobe PDF(1146Kb)  |  收藏  |  浏览/下载：220/58  |  提交时间：2016/08/22
Two new triterpene rhamnosides from Euphorbia dracunculoides Lam. 期刊论文
PHYTOCHEMISTRY LETTERS, 2015, 卷号: 12, 页码: 168-172
作者:  Wang, Li;  Cao, Pei;  Zang, Zhen;  Ma, Ya-Tuan;  Liu, Feng-Yi;  Li, Fei;  Wu, Xiang-Hua;  Huang, Sheng-Xiong;  Zhao, Yong;  Zhao,Y (reprint author),Yunnan Normal Univ,Coll Chem & Chem Engn,768 Juxian St,Kunming 650500,Peoples R China.;  sxhuang@mail.kib.ac.cn;  zhaooy@126.com
浏览  |  Adobe PDF(329Kb)  |  收藏  |  浏览/下载：227/64  |  提交时间：2015/07/20
Euphorbiaceae  Euphorbia Dracunculoides  Taraxerene-type  Triterpene Rhamnosides  
The Mechanism of Poly-Galloyl-Glucoses Preventing Influenza A Virus Entry into Host Cells 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 4, 页码: e94392
作者:  Ge, Hu;  Liu, Ge;  Xiang, Yang-Fei;  Wang, Yu;  Guo, Chao-Wan;  Chen, Nan-Hao;  Zhang, Ying-Jun;  Wang, Yi-Fei;  Kitazato, Kaio;  Xu, Jun
Adobe PDF(4149Kb)  |  收藏  |  浏览/下载：345/57  |  提交时间：2014/06/23
Receptor-binding Properties  Molecular-dynamics  Human Infection  Hemagglutinin  Transmission  Fusion  Origin  Amber