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Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
浏览  |  Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：338/77  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
New alkaloids sinomacutines A-E, and cephalonine-2-O-beta-D-glucopyranoside from rhizomes of Sinomenium acutum 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 46, 页码: 8893-8899
作者:  Li, Yan-Hong;  Li, Hong-Mei;  Li, Yan;  He, Juan;  Deng, Xu;  Peng, Li-Yan;  Gao, Ling-Huan;  Zhao, Qin-Shi;  Li, Rong-Tao;  Wu, Xing-De;  Li,RT (reprint author),Kunming Univ Sci & Technol,Fac Life Sci & Technol,Kunming 650500,Yunnan,Peoples R China.;  rongtaolikm@gmail.com;  wuxingde@mail.kib.ac.cn
浏览  |  Adobe PDF(673Kb)  |  收藏  |  浏览/下载：263/72  |  提交时间：2015/01/20
Sinomenium Acutum  Bistetrahydroisoquinoline Alkaloid  Acid Hydrolysis  Cytotoxicity  Anti-inflammatory Activity  
Aspergillines A-E, Highly Oxygenated Hexacyclic Indole-Tetrahydrofuran-Tetramic Acid Derivatives from Aspergillus versicolor 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 19, 页码: 5016-5019
作者:  Zhou, Min;  Miao, Ming-Ming;  Du, Gang;  Li, Xiao-Nian;  Shang, Shan-Zhai;  Zhao, Wei;  Liu, Zhi-Hua;  Yang, Guang-Yu;  Che, Chun-Tao;  Hu, Qiu-Fen;  Gao, Xue-Mei;  Hu,QF (reprint author),China Tobacco Yunnan Ind Co Ltd,Key Lab Tobacco Chem Yunnan Prov,Kunming 650231,Peoples R China.;  huqiufena@aliyun.com;  gao_xuemei@hotmail.com
Adobe PDF(277Kb)  |  收藏  |  浏览/下载：316/91  |  提交时间：2014/11/25
Cyclopiazonic Acid  Biological-activity  Biosynthesis  Flavus  
Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 10, 页码: 2353-2359
作者:  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Geng, Chang-An;  Zhao, Yong;  Wang, Li-Jun;  Guo, Rui-Hua;  Liang, Wen-Juan;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(3861Kb)  |  收藏  |  浏览/下载：309/74  |  提交时间：2014/06/23
Anti-hbv Activity  DehydroAndrographolide And  Andrographolide Derivatives  Structure-activity Relationships  Octanol-water Partition Coefficients  
Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 8, 页码: 1884-1888
作者:  Yan, Chen;  Huang, Li;  Liu, Hong-Chun;  Chen, Duo-Zhi;  Liu, Hai-Yang;  Li, Xiao-Hui;  Zhang, Yu;  Geng, Mei-Yu;  Chen, Quan;  Hao, Xiao-Jiang
Adobe PDF(1562Kb)  |  收藏  |  浏览/下载：299/45  |  提交时间：2014/06/23
Spiramine Derivative  Bax(-/-)/bak(-/-) Cells  Alpha  Apoptosis  Beta-unsaturated Ketone  Cytotoxicity  
Biologically Active Dichapetalins from Dichapetalum gelonioides 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2014, 卷号: 77, 期号: 4, 页码: 882-893
作者:  Jing, Shu-Xi;  Luo, Shi-Hong;  Li, Chun-Huan;  Hua, Juan;  Wang, Yan-Li;  Niu, Xue-Mei;  Li, Xiao-Nian;  Liu, Yan;  Huang, Chun-Shuai;  Wang, Ying;  Li, Sheng-Hong
Adobe PDF(392Kb)  |  收藏  |  浏览/下载：327/91  |  提交时间：2014/06/23
Defensive Sesterterpenoids  Glandular Trichomes  Triterpenoids  Constituents  Derivatives  Harbor  
Sesquiterpenoids and Diterpenes from Chamaecyparis obtusa var. breviramea f. crippsii 期刊论文
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2014, 卷号: 69, 期号: 3, 页码: 362-368
作者:  Xu, Jian;  Zeng, Guang-Zhi;  Liu, Yi-Mei;  Chen, Ke-Li;  Sun, Zhang-Hua;  Zhang, Yu-Mei;  Tan, Ning-Hua
浏览  |  Adobe PDF(184Kb)  |  收藏  |  浏览/下载：255/57  |  提交时间：2014/06/23
Chamaecyparis Obtusa Var. Breviramea F. Crippsii  Sesquiterpenoids  Diterpenes  Cytotoxicity  
Palladium-Catalyzed Unactivated C(sp(3))-H Bond Activation and intramolecular Amination of Carboxamides: A New Approach to beta-Lactams 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 2, 页码: 480-483
作者:  Sun, Wen-Wu;  Cao, Pei;  Mei, Ren-Qiang;  Li, Yue;  Ma, Yuan-Liang;  Wu, Bin
Adobe PDF(326Kb)  |  收藏  |  浏览/下载：626/63  |  提交时间：2014/04/09
C-h Activation  Carbon-hydrogen Bonds  Side-chain Sar  Acid Derivatives  Directing Group  Arylation  Functionalization  Inhibitors  Gamma  Construction  
Alkaloids from Ochrosia borbonica 期刊论文
HELVETICA CHIMICA ACTA, 2013, 卷号: 96, 期号: 12, 页码: 2288-2298
作者:  Zhang, Bing-Jie;  Yan, Ju-Ming;  Wu, Zi-Kun;  Liu, Ya-Ping;  Bao, Mei-Fen;  Cheng, Gui-Guang;  Luo, Xiao-Dong;  Cai, Xiang-Hai;  Li, Yan
Adobe PDF(208Kb)  |  收藏  |  浏览/下载：305/80  |  提交时间：2014/01/21
Ochrosia Borbonica  Indole Alkaloids  Alkaloids  Ochroborines a And b  Cytotoxic Activity  
Scopariusic Acid, a New Meroditerpenoid with a Unique Cyclobutane Ring Isolated from Isodon scoparius 期刊论文
ORGANIC LETTERS, 2013, 卷号: 15, 期号: 17, 页码: 4446-4449
作者:  Zhou, Min;  Zhang, Hai-Bo;  Wang, Wei-Guang;  Gong, Ning-Bo;  Zhan, Rui;  Li, Xiao-Nian;  Du, Xue;  Li, Li-Mei;  Li, Yan;  Lu, Yang;  Pu, Jian-Xin;  Sun, Han-Dong
Adobe PDF(792Kb)  |  收藏  |  浏览/下载：432/112  |  提交时间：2014/01/21
2+2 Cycloadditions  Biyouyanagin-a  Biological Evaluation  Incarvillea-sinensis  Revised Structure  Skeleton  Littoralisone  Alkaloids  Diterpene