Alkaloids from Ochrosia borbonica
Zhang, Bing-Jie1; Yan, Ju-Ming1; Wu, Zi-Kun2; Liu, Ya-Ping1; Bao, Mei-Fen1; Cheng, Gui-Guang1; Luo, Xiao-Dong1; Cai, Xiang-Hai1; Li, Yan1
Corresponding AuthorCai,XH (reprint author),Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China. ; ;
AbstractTen new monoterpenoid indole alkaloids, ochroborines A and B (1 and 2, resp.), 10-hydroxyisovallesiachotamine (3), 10-hydroxyisositsirikine (4), 10,11-dimethoxysitsirikine (5), 10-methoxyapoyohimbine (6), 10-hydroxyakuammidine (7), akuammidine 17-O--D-glucoside (8), 15-hydroxyapparicine (9), and 15-hydroxy-10-methoxyapparicine (10), and 24 known alkaloids were isolated from leaves and twigs of Ochrosia borbonica J.F.Gmel. These structures were elucidated based on 1D- and 2D-NMR, FT-IR, UV, and MS data. 10-Hydroxyisovallesiachotamine (3), ellipticine, and 10-methoxyellipticine showed cytotoxic activities against five human cancer cell lines.
KeywordOchrosia Borbonica Indole Alkaloids Alkaloids Ochroborines a And b Cytotoxic Activity
Indexed BySCI ; IC
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000328394400018
Citation statistics
Cited Times:11[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Affiliation1.Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
2.Kunming Inst Bot, Lijiang Forest Ecosyst Res Stn, Kunming 650201, Peoples R China
Recommended Citation
GB/T 7714
Zhang, Bing-Jie,Yan, Ju-Ming,Wu, Zi-Kun,et al. Alkaloids from Ochrosia borbonica[J]. HELVETICA CHIMICA ACTA,2013,96(12):2288-2298.
APA Zhang, Bing-Jie.,Yan, Ju-Ming.,Wu, Zi-Kun.,Liu, Ya-Ping.,Bao, Mei-Fen.,...&Li, Yan.(2013).Alkaloids from Ochrosia borbonica.HELVETICA CHIMICA ACTA,96(12),2288-2298.
MLA Zhang, Bing-Jie,et al."Alkaloids from Ochrosia borbonica".HELVETICA CHIMICA ACTA 96.12(2013):2288-2298.
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