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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：183/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Polycyclic polyprenylated acylphloroglucinol derivatives with neuroprotective effects from Hypericum monogynum 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 页码: 9
作者:  Zeng, Yan-Rong;  Li, Ya-Na;  Lou, Hua-Yong;  Jian, Jun-You;  Gu, Wei;  Huang, Lie-Jun;  Du, Guan-Hua;  Yuan, Chun-Mao;  Hao, Xiao-Jiang
Adobe PDF(1233Kb)  |  收藏  |  浏览/下载：249/42  |  提交时间：2020/03/18
Hypericum monogynum  polycyclic polyprenylated acylphloroglucinols (PPAPs)  neuroprotective effects  structure-activity relationship  
Commiphorines A and B, unprecedented sesquiterpenoid dimers from Resina Commiphora with striking activities on anti-inflammation and lipogenesis inhibition 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 23, 页码: 3825-3833
作者:  Dong, Lu;  Qin, Da-Peng;  Di, Qian-Qian;  Liu, Ying;  Chen, Wei-Lin;  Wang, Shu-Mei;  Cheng, Yong-Xian
浏览  |  Adobe PDF(2250Kb)  |  收藏  |  浏览/下载：192/53  |  提交时间：2020/03/17
Identification and Characterization of ShSPI, a Kazal-Type Elastase Inhibitor from the Venom of Scolopendra Hainanum 期刊论文
TOXINS, 2019, 卷号: 11, 期号: 12, 页码: 13
作者:  Luan, Ning;  Zhao, Qiyu;  Duan, Zilei;  Ji, Mengyao;  Xing, Meichen;  Zhu, Tengyu;  Mwangi, James;  Rong, Mingqiang;  Liu, Jiangxin;  Lai, Ren
浏览  |  Adobe PDF(2415Kb)  |  收藏  |  浏览/下载：194/34  |  提交时间：2020/03/18
centipede  kazal-type inhibitor  human neutrophils elastase  ShSPI  
Anti-inflammatory evaluation and structure-activity relationships of diterpenoids isolated from Euphorbia hylonoma 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 10
作者:  Wei, Wen-Jun;  Qi, Weiyan;  Gao, Xin-Mei;  Feng, Ke-Na;  Ma, Kai-Liang;  Li, Hang-Ying;  Li, Ya;  Gao, Kun
浏览  |  Adobe PDF(2502Kb)  |  收藏  |  浏览/下载：193/42  |  提交时间：2020/03/18
Euphorbia hylonoma  ent-Isopimarane  ent-Rosane  Anti-inflammatory  
Four new sesquiterpene derivatives from Dendrobium findlayanum 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 900-905
作者:  Yang Dan;  Cheng Zhong-Quan;  Zi Cheng-Ting;  Yang Liu;  Dong Fa-Wu;  Hu Jiang-Miao;  Zhou Jun
浏览  |  Adobe PDF(477Kb)  |  收藏  |  浏览/下载：170/35  |  提交时间：2020/03/18
Dendrobium findlayanum  Sesquiterpene derivatives  Alloaromadendrane  Cyclopacamphane  
C-28 steroids from the fruiting bodies of Ganoderma resinaceum with potential anti-inflammatory activity 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 168, 页码: 8
作者:  Shi, Qiangqiang;  Huang, Yanjie;  Su, Haiguo;  Gao, Ya;  Peng, Xingrong;  Zhou, Lin;  Li, Xiaonian;  Qiu, Minghua
浏览  |  Adobe PDF(824Kb)  |  收藏  |  浏览/下载：244/73  |  提交时间：2020/03/26
Ganoderma resinaceum boud  Ganodermataceae  Ergostane-type  Steroids  Anti-inflammatory activity  
Leucosceptroid B from glandular trichomes of Leucosceptrum canum reduces fat accumulation in Caenorhabditis elegans through suppressing unsaturated fatty acid biosynthesis 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 892-899
作者:  Ling Yi;  Teng Lin-Lin;  Hua Juan;  Li De-Sen;  Luo Shi-Hong;  Liu Yan-Chun;  Liu Yan;  Li Sheng-Hong
浏览  |  Adobe PDF(1517Kb)  |  收藏  |  浏览/下载：298/52  |  提交时间：2020/03/18
Sesterterpenoid  Leucosceptroid B  Leucosceptrum canum  Caenorhabditis elegans  Fat accumulation  Fatty acid biosynthesis  Antilipemic agent  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：198/30  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Structural determination of eleven new preschisanartane-type schinortriterpenoids from two Schisandra species and structural revision of preschisanartanin J using NMR computation method 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 970-981
作者:  Hu Kun;  Li Xing-Ren;  Tang Jian-Wei;  Li Xiao-Nian;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1250Kb)  |  收藏  |  浏览/下载：182/52  |  提交时间：2020/03/18
Schisandra sphaerandra  Schisandra rubriflora  Preschisanartane-type schinortriterpenoids  Structural revision  Quantum chemical calculation of NMR parameters