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Design, Synthesis, and Evaluation of the COX-2 Inhibitory Activities of New 1,3-Dihydro-2H-indolin-2-one Derivatives 期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 12, 页码: 4668
作者:  Pan,Taohua;  He,Maofei;  Deng,Lulu;  Li,Jiang;  Fan,Yanhua;  Hao,Xiaojiang;  Mu,Shuzhen
浏览  |  Adobe PDF(3057Kb)  |  收藏  |  浏览/下载：33/8  |  提交时间：2024/05/09
oxindoles  alpha,beta-unsaturated ketone  anti-inflammatory  COX-2 inhibitory activity  ANTIINFLAMMATORY ACTIVITY  NATURAL-PRODUCTS  OXINDOLE-DERIVATIVES  NITRIC-OXIDE  POTENT  CYCLOOXYGENASE-2  DISCOVERY  PAIN  LIABILITY  
Inverse Electron-Demanding Diels-Alder Reactions in the Chemical Synthesis of Prenylated Indole Alkaloids Containing a Bicycle[2.2.2]diazaoctane Moiety: A Theoretical Study 期刊论文
CHEMISTRY-AN ASIAN JOURNAL, 2023, 卷号: 18, 期号: 7
作者:  Xu,Wenqiang;  Sun,Tian-Yu;  Di,Yingtong;  Hao,Xiaojiang;  Wu,Yun-Dong
浏览  |  Adobe PDF(8430Kb)  |  收藏  |  浏览/下载：10/1  |  提交时间：2024/07/10
alkaloids  chemical synthesis  inverse-electron demanding Diels-Alder reaction  reaction mechanisms  theoretical study  BIOMIMETIC TOTAL-SYNTHESIS  CORRELATED MOLECULAR CALCULATIONS  MARINE-DERIVED FUNGUS  GAUSSIAN-BASIS SETS  (-)-VERSICOLAMIDE B  ORBITAL METHODS  BREVIANAMIDE-A  STEPHACIDIN-A  MODEL  CONCISE  
Tabernaesine J, a Novel Vincamine-Type Indole Alkaloid with 6/5/6/6/6/5/5 Heptacyclic-Ring System Scaffold from Tabernaemontana pachysiphon 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2022, 卷号: 40, 期号: 4, 页码: 475-479
作者:  Yi,Wen-Fang;  Adelakun,Tiwalade A.;  Bai,Xue;  Zhang,Yu;  Hao,Xiao-Jiang
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Natural products  Alkaloids  Structure elucidation  Tabernaemontana pachysiphon  Tabernaesine J  BISINDOLE ALKALOIDS  A-I  ALGORITHM  
Hypermogins A-D, four highly modified polycyclic polyprenylated acylphloroglucinols from Hypericum monogynum 期刊论文
TETRAHEDRON LETTERS, 2021, 卷号: 64, 页码: 152733
作者:  Zeng,Yanrong;  Yang,Jue;  Li,Yanan;  Gu,Wei;  Huang,Liejun;  Yi,Ping;  Yuan,Chunmao;  Hao,Xiaojiang
收藏  |  浏览/下载：74/0  |  提交时间：2022/04/02
Hypericum monogynum  PPAPs  Multidrug resistance reversal activity  PHLOROGLUCINOL DERIVATIVES  
Hypermonones A-I, New Polyprenylated Acylphloroglucinols from Hypericum monogynum with Multidrug Resistance Reversal Activity 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 9, 页码: 2422-2432
作者:  Zeng,Yan-Rong;  Li,Ya-Nan;  Yang,Jue;  Yi,Ping;  Huang,Lei;  Huang,Lie-Jun;  Gu,Wei;  Hu,Zhan-Xing;  Li,Yan-Mei;  Yuan,Chun-Mao;  Hao,Xiao-Jiang
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Hypericum monogynum  Phytochemistry  Structure elucidation  Biological activity  Multidrug resistance reversal activity  P-GLYCOPROTEIN  MODULATORS  CANCER  
New Secodaphnane-Type Alkaloids with Cytotoxic Activities from Daphniphyllum angustifolium Hutch. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 4, 页码: 453-457
作者:  Lu,Qing-Yun;  Zhang,Jia-Hui;  Li,Ying-Yao;  Pu,Xue-Xue;  Zhang,Cui-Shan;  Liu,Shuai;  Wan,Jia-Jia;  Di,Ying-Tong;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(949Kb)  |  收藏  |  浏览/下载：129/45  |  提交时间：2022/04/02
Voacafrines A-N, aspidosperma-type monoterpenoid indole alkaloids from Voacanga africana with AChE inhibitory activity 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 181, 页码: 112566
作者:  Zhao,Qian;  Zhu,Wen-Tao;  Ding,Xiao;  Huo,Zong-Qing;  Donkor,Paul O.;  Adelakun,Tiwalade A.;  Hao,Xiao-Jiang;  Zhang,Yu
浏览  |  Adobe PDF(3237Kb)  |  收藏  |  浏览/下载：142/27  |  提交时间：2022/04/02
Voacanga africana stapf  Apocynaceae  Monoterpenoid indole alkaloids  Voacafrines A-N  AChE inhibitory activity  
Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1175-1184
作者:  Chen,Duo-Zhi;  Fan,Shi-Rui;  Yang,Bi-Juan;  Yao,Huo-Chun;  Wang,Yi-Ting;  Cai,Jie-Yun;  Jing,Chen-Xu;  Pan,Zi-Hao;  Luo,Miao;  Yuze,Yan-Qiu;  Liu,Guang-Jin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(8772Kb)  |  收藏  |  浏览/下载：112/30  |  提交时间：2022/04/02
PROTEIN  CORONAVIRUSES  SARS  PARTICLES  INSIGHTS  HSC70  
Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway 期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
作者:  Yang,Hao-Jie;  Li,Ya-Nan;  Yan,Chen;  Yang,Jue;  Zeng,Yan-Rong;  Yi,Ping;  Li,Yan-Mei;  Hao,Xiao-Jiang;  Yuan,Chun-Mao
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Dysoxylum gotadhora  Rocaglaol derivatives  HCT116  Cytotoxic activity  MAPK pathway  FLAVAGLINES  
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
作者:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
浏览  |  Adobe PDF(2105Kb)  |  收藏  |  浏览/下载：118/48  |  提交时间：2022/04/02
Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA