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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：172/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
浏览  |  Adobe PDF(2215Kb)  |  收藏  |  浏览/下载：221/51  |  提交时间：2020/03/18
Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
作者:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
浏览  |  Adobe PDF(1542Kb)  |  收藏  |  浏览/下载：275/73  |  提交时间：2020/03/18
delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：192/30  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Flavipesines A and B and Asperchalasines E-H: Cytochalasans and Merocytochalasans from Aspergillus flavipes 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 11, 页码: 2994-3001
作者:  Zhang, Xiaotian;  Yang, Lu;  Wang, Wenjing;  Wu, Zhaodi;  Wang, Jianping;  Sun, Weiguang;  Li, Xiao-Nian;  Chen, Chunmei;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1885Kb)  |  收藏  |  浏览/下载：132/22  |  提交时间：2020/03/18
12 beta-Acetyloxyperforatin, a New Limonoid from Harrisonia Perforata 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 19, 页码: 2830-2836
作者:  Gui, Peng-Yan;  Yan, Xiao-Hui;  Yuan, Wen-Juan;  Ma, Yuan-Liang;  Ding, Xiao;  Liu, Shuai;  Di, Ying-Tong;  Zhu, Wei-Ming;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(919Kb)  |  收藏  |  浏览/下载：341/163  |  提交时间：2019/09/10
Harrisonia perforata  limonoid  12 beta-Acetyloxyperforatin  computational modelling  
Recombinant polyphenol oxidases for production of theaflavins from tea polyphenols 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 134, 页码: 139-145
作者:  Zeng, Jun;  Du, Gang;  Shao, Xue;  Feng, Ke-Na;  Zeng, Ying
浏览  |  Adobe PDF(1259Kb)  |  收藏  |  浏览/下载：155/44  |  提交时间：2019/08/19
Theaflavins  Recombinant polyphenol oxidase  Mesoporous silica  
Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 228-235
作者:  Yang, Tong-Hua;  Yan, De-Xiu;  Huang, Xiao-Yan;  Hou, Bo;  Ma, Yun-Bao;  Peng, Hua;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Geng, Chang-An
浏览  |  Adobe PDF(2111Kb)  |  收藏  |  浏览/下载：259/28  |  提交时间：2019/09/10
Terminthia paniculata (Wall. ex G. Don) CY Wu & TL Ming  Anacardiaceae  Termipaniculatones A-F  Chalcone-flavonone heterodimers  Xanthine oxidase inhibitors  Anti-gout potency  
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3136Kb)  |  收藏  |  浏览/下载：168/56  |  提交时间：2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
浏览  |  Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：254/59  |  提交时间：2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis