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Nonasaccharide Inhibits Intrinsic Factor Xase Complex by Binding to Factor IXa and Disrupting Factor IXa-Factor VIIIa Interactions 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 期号: 5, 页码: 705-715
作者:  Xiao, Chuang;  Zhao, Longyan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(740Kb)  |  收藏  |  浏览/下载：253/69  |  提交时间：2019/06/24
nonasaccharide from fucosylated glycosaminoglycan  intrinsic factor Xase complex  factor IXa  anticoagulant  
Synthesis of Fucosylated Chondroitin Sulfate Nonasaccharide as a Novel Anticoagulant Targeting Intrinsic Factor Xase Complex 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 39, 页码: 12880-12885
作者:  Zhang, Xiao;  Liu, Huiying;  Lin, Lisha;  Yao, Wang;  Zhao, Jinhua;  Wu, Mingyi;  Li, Zhongjun
浏览  |  Adobe PDF(1568Kb)  |  收藏  |  浏览/下载：220/54  |  提交时间：2018/10/22
Anticoagulants  Drug Discovery  Fucosylated Chondroitin Sulfate  Glycosaminoglycans  Oligosaccharides  
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
作者:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(1313Kb)  |  收藏  |  浏览/下载：231/39  |  提交时间：2018/10/07
Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis  
Structural analysis and anticoagulant activities of three highly regular fucan sulfates as novel intrinsic factor Xase inhibitors 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 195, 页码: 257-266
作者:  Shang, Feineng;  Mou, Rongrong;  Zhang, Zhidong;  Gao, Na;  Lin, Lisha;  Li, Zhongkun;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(2021Kb)  |  收藏  |  浏览/下载：352/67  |  提交时间：2018/07/16
Fucan Sulfate  Chemical Structure  Anticoagulant  Polysaccharide  Sea Cucumber  
Enzyme-Assisted Extraction Optimization, Characterization and Antioxidant Activity of Polysaccharides from Sea Cucumber Phyllophorus proteus 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 590
作者:  Qin, Yujing;  Yuan, Qingxia;  Zhang, Yuexing;  Li, Jialu;  Zhu, Xinjiao;  Zhao, Lingling;  Wen, Jing;  Liu, Jikai;  Zhao, Longyan;  Zhao, Jinhua
浏览  |  Adobe PDF(5270Kb)  |  收藏  |  浏览/下载：282/74  |  提交时间：2018/07/02
Sea Cucumber  Polysaccharide  Enzyme-assisted Extraction  Characterization  Antioxidant Activity  
Structural analysis and biological activity of a highly regular glycosaminoglycan from Achatina fulica 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 181, 页码: 433-441
作者:  Liu, Jie;  Zhou, Lutan;  He, Zhicheng;  Gao, Na;  Shang, Feineng;  Xu, Jianping;  Li, Zi;  Yang, Zengming;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(2955Kb)  |  收藏  |  浏览/下载：295/66  |  提交时间：2018/05/08
Snail  Glycosaminoglycan  Chemical Structure  Heparin  Anticoagulant  
Plasma contact activation by a fucosylated chondroitin sulfate and its structure-activity relationship study 期刊论文
GLYCOBIOLOGY, 2018, 卷号: 28, 期号: 10, 页码: 754-764
作者:  Lin, Lisha;  Xu, Li;  Xiao, Chuang;  Zhou, Lutan;  Gao, Na;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(595Kb)  |  收藏  |  浏览/下载：196/50  |  提交时间：2019/03/29
The initiation and effects of plasma contact activation: an overview 期刊论文
INTERNATIONAL JOURNAL OF HEMATOLOGY, 2017, 卷号: 105, 期号: 3, 页码: 235-243
作者:  Lin, Lisha;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(424Kb)  |  收藏  |  浏览/下载：260/44  |  提交时间：2017/05/19
Contact Activation  Kallikrein-kinin  Coagulation  Inflammation  Factor Xii  
Interactions between depolymerized fucosylated glycosaminoglycan and coagulation proteases or inhibitors 期刊论文
THROMBOSIS RESEARCH, 2016, 卷号: 146, 页码: 59-68
作者:  Xiao, Chuang;  Lian, Wu;  Zhou, Lutan;  Gao, Na;  Xua, Li;  Chen, Jun;  Wu, Mingyi;  Peng, Wenlie;  Zhao, Jinhua
浏览  |  Adobe PDF(5739Kb)  |  收藏  |  浏览/下载：366/94  |  提交时间：2017/01/05
Fucosylated Glycosaminoglycan  Coagulation Proteases  Biolayer Interferometry  Binding Kinetics  Structure-activity Relationship  
Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycan 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 卷号: 112, 期号: 27, 页码: 8284-8289
作者:  Zhao, Longyan;  Wu, Mingyi;  Xiao, Chuang;  Yang, Lian;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Chen, Jun;  Chen, Jianchao;  Liu, Jikai;  Qin, Hongbo;  Zhao, Jinhua
浏览  |  Adobe PDF(1067Kb)  |  收藏  |  浏览/下载：331/44  |  提交时间：2015/12/17
Anticoagulant  Inhibitors  Oligosaccharides  Carbohydrates  Drug Discovery