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Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 11, 页码: UNSP 1934
作者:  Song, Lihua;  Wang, Zhe;  Wang, Yurong;  Guo, Di;  Yang, Jianhong;  Chen, Lijuan;  Tan, Ninghua
浏览  |  Adobe PDF(4110Kb)  |  收藏  |  浏览/下载：161/38  |  提交时间：2018/05/08
Ra-xii  Cyclopeptide  Autophagy  Apoptosis  Mtor  Hepg2 Liver Cancer Cells  
Virtual screening of B-Raf kinase inhibitors: A combination of pharmacophore modelling, molecular docking, 3D-QSAR model and binding free energy calculation studies 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2017, 卷号: 70, 页码: 186-190
作者:  Zhang, Wen;  Qiu, Kai-Xiong;  Yu, Fang;  Xie, Xiao-Guang;  Zhang, Shu-Qun;  Chen, Ya-Juan;  Xie, Hui-Ding
浏览  |  Adobe PDF(371Kb)  |  收藏  |  浏览/下载：153/28  |  提交时间：2017/12/11
B-raf Kinase Inhibitors  Virtual Screening  Pharmacophore  Molecular Docking  3d Qsar  Binding Free Energy Calculation  
Potential role of CYP1B1 in the development and treatment of metabolic diseases 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2017, 卷号: 178, 页码: 18-30
作者:  Li, Fei;  Zhu, Weifeng;  Gonzalez, Frank J.
浏览  |  Adobe PDF(2083Kb)  |  收藏  |  浏览/下载：188/62  |  提交时间：2017/11/20
Cyp1b1  Metabolic Diseases  Metabolic Pathways  Metabolomics  
Meroterpenoids with Antitumor Activities from Guava (Psidium guajava) 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2017, 卷号: 65, 期号: 24, 页码: 4993-4999
作者:  Qin, Xu-Jie;  Yu, Qian;  Yan, Huan;  Khan, Afsar;  Feng, Mi-Yan;  Li, Pan-Pan;  Hao, Xiao-Jiang;  An, Lin-Kun;  Liu, Hai-Yang
浏览  |  Adobe PDF(3439Kb)  |  收藏  |  浏览/下载：300/91  |  提交时间：2017/07/31
Guava  Meroterpenoids  Cytotoxicity  Dna Topoisomerase i Inhibitors  Antiproliferative Activity  
Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 11, 页码: 4680-4692
作者:  Qu, Chunrong;  Ding, Mingmin;  Zhu, Yingmin;  Lu, Yungang;  Du, Juan;  Miller, Melissa;  Tian, Jinbin;  Zhu, Jinmei;  Xui, Jian;  Wen, Meng;  Er-Bu, Aga;  Wan, Jule;  Xiao, Yuling;  Wu, Meng;  McManus, Owen B.;  Li, Min;  Wu, Jilin;  Luo, Huai-Rong;  Cao, Zhengyu;  Shen, Bing;  Wang, Hongbo;  Zhu, Michael X.;  Hong, Xuechuan
浏览  |  Adobe PDF(1969Kb)  |  收藏  |  浏览/下载：220/78  |  提交时间：2017/08/29
Four new diterpenoid alkaloids with antitumor effect from Aconitum nagarum var. heterotrichum 期刊论文
CHINESE CHEMICAL LETTERS, 2017, 卷号: 28, 期号: 2, 页码: 358-361
作者:  Zhao, Da-Ke;  Shi, Xing-Qiao;  Zhang, Li-Mei;  Yang, Dong-Qiong;  Guo, Hua-Chun;  Chen, Yan-Ping;  Shen, Yong
浏览  |  Adobe PDF(1397Kb)  |  收藏  |  浏览/下载：205/43  |  提交时间：2017/04/19
Ranunculaceae  Aconitum Nagarum Var. Heterotrichum  Diterpenoid Alkaloids  Nagaconitines A-d  Antitumor Activity  
Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 2, 页码: 2681-2693
作者:  Cheng, Xin;  Liu, Yong-Qiang;  Wang, Gui-Zhen;  Yang, Li-Na;  Lu, Yong-Zhi;  Li, Xin-Chun;  Zhou, Bo;  Qu, Li-Wei;  Wang, Xiao-Lu;  Cheng, Yong-Xian;  Liu, Jinsong;  Tao, Sheng-Ce;  Zhou, Guang-Biao
Adobe PDF(7649Kb)  |  收藏  |  浏览/下载：189/25  |  提交时间：2017/04/18
Proteome Microarray  6-o-angeloylplenolin  Stat3 Inhibitor  Skp2  Lung Cancer  
Cognitive-enhancing effects of beta-sitosterol in vanadium-induced neurotoxicity in mice 期刊论文
JOURNAL OF NEUROCHEMISTRY, 2017, 卷号: 142, 页码: 238-238
作者:  Adebiyi,O.;  Olayemi,F.;  Olopade,J.;  Ning-Hua,T.
Adobe PDF(878Kb)  |  收藏  |  浏览/下载：168/76  |  提交时间：2017/10/23
Eriocalyxin B, a Novel Autophagy Inducer, Exerts Anti-tumor Activity Through the Suppression of Akt/mTOR/p70S6K Signaling Pathway In breast Cancer 期刊论文
Biochemical Pharmacology, 2017, 卷号: 142, 页码: 58–70
作者:  Xunian Zhou;  Grace Gar-Lee Yue;  Andrew Man-Lok Chan;   Stephen Kwok-Wing Tsui;  Kwok-Pui Fung;   Handong Sun;  Jianxin Pu;  Clara Bik-San Lau
Adobe PDF(5871Kb)  |  收藏  |  浏览/下载：218/56  |  提交时间：2017/11/20
Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells 期刊论文
ONCOLOGY LETTERS, 2017, 卷号: 13, 期号: 3, 页码: 1672-1680
作者:  Yuan,Yan;  Du,Yong;  Hu,Xiao-Ye;  Liu,Mei-Yuan;  Du,Ji-Ke;  Liu,Xue-Min;  Yu,Hong-En;  Wang,Tian-Zhu;  Pu,Jian-Xin;  Zhong,Qian;  Zou,Qing-Feng
Adobe PDF(1897Kb)  |  收藏  |  浏览/下载：346/46  |  提交时间：2017/10/23
Side Population  C-myc  Cancer  Expression  Radioresistance  Identification  Subpopulation  Combination  Pathway  Domain  Longikaurin a  Nasopharyngeal Carcinoma  Cancer Stem Cells