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Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105067
作者:  Song,Ying-Ying;  Jiang,Jian-Bing;  Yan,Yong-Ming;  Cheng,Yong-Xian
浏览  |  Adobe PDF(4755Kb)  |  收藏  |  浏览/下载：121/43  |  提交时间：2022/04/02
Belamcanda chinensis  Triterpenoids  TGF-beta 1  Kidney proximal tubular cells  TGF-BETA  TRITERPENOIDS  CONSTITUENTS  
Artematrovirenins A-P, guaiane-type sesquiterpenoids with cytotoxicities against two hepatoma cell lines from Artemisia atrovirens 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105072
作者:  Su,Li-Hua;  Ma,Yun-Bao;  Geng,Chang-An;  Li,Tian-Ze;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xin;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(2611Kb)  |  收藏  |  浏览/下载：159/77  |  提交时间：2022/04/02
Artemisia atrovirens  guaiane-type sesquiterpenoids  artematrovirenins A-P  HepG2 and Huh7 cell lines  antihepatic cytotoxicity  LACTONES  CONSTITUENTS  GUAIANOLIDES  
Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载：129/41  |  提交时间：2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(2223Kb)  |  收藏  |  浏览/下载：134/56  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols A(1)-A(16)  PTP1B/TCPTP selective inhibitors  alpha-glucosidase inhibitors  Antidiabetic effects  THEORETICAL CALCULATION  ABSOLUTE-CONFIGURATION  SEEDS  BLEPHAROCALYXINS  ADDUCT  MOIETY  
Functional triterpenoids from medicinal fungi Ganoderma applanatum: A continuous search for antiadipogenic agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104977
作者:  Su,Hai-Guo;  Wang,Qian;  Zhou,Lin;  Peng,Xing-Rong;  Xiong,Wen-Yong;  Qiu,Ming -Hua
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Ganoderma applanatum  Lanostane triterpenoids  Antiadipogenic effects  LANOSTANE-TYPE TRITERPENOIDS  ACID  
FPR2-based anti-inflammatory and anti-lipogenesis activities of novel meroterpenoid dimers from Ganoderma 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105338
作者:  Peng,Xing-Rong;  Wang,Qian;  Wang,Hui-Rong;  Hu,Kun;  Xiong,Wen-Yong;  Qiu,Ming-Hua
浏览  |  Adobe PDF(7004Kb)  |  收藏  |  浏览/下载：102/15  |  提交时间：2022/04/02
Ganoderma applanatum  Meroterpenoid dimers  Molecular docking  Anti-lipogenesis  FPR2-based inflammation  INDUCED INSULIN-RESISTANCE  ADIPOCYTE DIFFERENTIATION  OBESITY  INFLAMMATION  DEFICIENCY  MACROPHAGES  ACTIVATION  EXPRESSION  LIGAND  MICE  
Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104767
作者:  Guo,Sheng;  Xie,Hang;  Lei,Yu;  Liu,Bin;  Zhang,Li;  Xu,Yechun;  Zuo,Zhili
浏览  |  Adobe PDF(3181Kb)  |  收藏  |  浏览/下载：109/34  |  提交时间：2022/04/02
SARS-CoV-2  Main protease  Virtual screening  Biochemical evaluation  
New cytotoxic dichapetalins in the leaves of Phyllanthus acidus: Identification, quantitative analysis, and preliminary toxicity assessment 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105125
作者:  Geng,Hui-Chun;  Zhu,Hong-Tao;  Yang,Wei-Nong;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
浏览  |  Adobe PDF(774Kb)  |  收藏  |  浏览/下载：104/20  |  提交时间：2022/04/02
Phyllanthus acidus  Euphorbiaceae  Dichapetalins  Pacidusins A-D  Cytotoxicity  TRITERPENOIDS  CONSTITUENTS  
Non-volatile acylphloroglucinol components from Eucalyptus robusta inhibit Zika virus by impairing RdRp activity of NS5 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105303
作者:  Yao,Zhai-Wen;  Liu,Hui;  Zhou,Rui;  Feng,Mi-Yan;  Wang,Fang;  Qin,Xu-Jie;  Chen,Xiu-Xiu;  Zheng,Chang-Bo;  Luo,Rong-Hua;  Yang,Liu-Meng;  Cen,Shan;  Xiong,Si-Dong;  Liu,Hai-Yang;  Zheng,Yong-Tang
浏览  |  Adobe PDF(2139Kb)  |  收藏  |  浏览/下载：107/38  |  提交时间：2022/04/02
Eucalyptus robusta  Acylphloroglucinol dimer  Eucalyprobusone G  Anti-ZIKV agent  NS5 RdRp  INFECTION  BINDING  GROWTH  
Lepipyrrolins A-B, two new dimeric pyrrole 2-carbaldehyde alkaloids from the tubers of Lepidium meyenii 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104834
作者:  Liu,Jun-Hong;  Zhang,Ran-Ran;  Peng,Xing-Rong;  Ding,Zhong-Tao;  Qiu,Ming-Hua
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Lepidium meyenii  Pyrrole 2-carbaldehyde alkaloids  Dimers  Cytotoxicity  THIOHYDANTOIN DERIVATIVES  STRUCTURAL ELUCIDATION  MACA  MACAMIDES  WALP.  PLANT  CROP