Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells

doi:10.1016/j.bioorg.2021.105067

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	Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells
	Song,Ying-Ying ; Jiang,Jian-Bing ; Yan,Yong-Ming ; Cheng,Yong-Xian
	2021
发表期刊	BIOORGANIC CHEMISTRY
ISSN	0045-2068
卷号	114 页码:105067
摘要	Belamcandaoids A-N (1-14), fourteen new triterpenoids were isolated from the seeds of Belamcanda chinensis. Their structures including absolute configurations were assigned by using spectroscopic, computational, and crystallographic methods. All the compounds except 1 and 2 are 3,4-seco-triterpenoids belonging to fernane type. Biological evaluation results indicated that 3 and 13 could reduce fibronectin and collagen I expression respectively in TGF-beta 1 induced kidney proximal tubular cells.
关键词	Belamcanda chinensis Triterpenoids TGF-beta 1 Kidney proximal tubular cells TGF-BETA TRITERPENOIDS CONSTITUENTS
DOI	10.1016/j.bioorg.2021.105067
WOS记录号	WOS:000689510400003
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73741
专题	中国科学院昆明植物研究所
作者单位	1.[Jiang, Jian-Bing 2.Yan, Yong-Ming 3.Shenzhen Univ, Sch Pharmaceut Sci, Inst Inheritance Based Innovat Chinese Med, Hlth Sci Ctr, Shenzhen 518060, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 5.Hanshan Normal Univ, Sch Life Sci & Food Engn, Guangdong Key Lab Funct Subst Med Edible Resource, Chaozhou 521041, Peoples R China
推荐引用方式 GB/T 7714	Song,Ying-Ying,Jiang,Jian-Bing,Yan,Yong-Ming,et al. Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells[J]. BIOORGANIC CHEMISTRY,2021,114:105067.
APA	Song,Ying-Ying,Jiang,Jian-Bing,Yan,Yong-Ming,&Cheng,Yong-Xian.(2021).Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells.BIOORGANIC CHEMISTRY,114,105067.
MLA	Song,Ying-Ying,et al."Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells".BIOORGANIC CHEMISTRY 114(2021):105067.

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