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Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis 期刊论文
PHYTOMEDICINE, 2020
作者:  Wang Yu-Ling;  Wu Wei;  Su Yong-Nan;  Ai Zhi-Peng;  Mou Han-Chuan;  Wan Luo-Sheng;  Luo Ying;  Qiu Ming-Hua;  Zhang Ji-Hong
浏览  |  Adobe PDF(7972Kb)  |  收藏  |  浏览/下载：137/35  |  提交时间：2021/01/05
Computational simulation studies on the binding selectivity of Wee1 and Checkpoint kinase 1 by molecular dynamics simulation combined with free energy calculations 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020
作者:  Li, Yaping;  Liu, Xingyong;  Zhang, Shuqun;  Wang, Liangliang;  Zhang, Li;  Zuo, Zhili
浏览  |  Adobe PDF(2066Kb)  |  收藏  |  浏览/下载：179/22  |  提交时间：2021/01/05
RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 9, 页码: 14
作者:  Guo, Di;  Wang, Yurong;  Wang, Jing;  Song, Lihua;  Wang, Zhe;  Mao, Bingyu;  Tan, Ninghua
浏览  |  Adobe PDF(9639Kb)  |  收藏  |  浏览/下载：152/28  |  提交时间：2019/07/29
RA-XII  lipogenesis  SCAP  SREBP  liver cancer  
Cognitive-enhancing effects of beta-sitosterol in vanadium-induced neurotoxicity in mice 期刊论文
JOURNAL OF NEUROCHEMISTRY, 2017, 卷号: 142, 页码: 238-238
作者:  Adebiyi,O.;  Olayemi,F.;  Olopade,J.;  Ning-Hua,T.
浏览  |  Adobe PDF(878Kb)  |  收藏  |  浏览/下载：160/70  |  提交时间：2017/10/23
N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2016, 卷号: 35
作者:  Wang, Min;  Zhou, Ankun;  An, Tao;  Kong, Lingmei;  Yu, Chunlei;  Liu, Jianmei;  Xia, Chengfeng;  Zhou, Hongyu;  Li, Yan
浏览  |  Adobe PDF(1734Kb)  |  收藏  |  浏览/下载：202/31  |  提交时间：2016/06/27
N-hydroxyphthalimide  Mtor  Inhibitor  Cancer  Mitochondrial Apoptosis  
RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
作者:  Leung,Hoi-Wing;  Zhao,Si-Meng;  Yue,Grace Gar-Lee;  Lee,Julia Kin-Ming;  Fung,Kwok-Pui;  Leung,Ping-Chung;  Tan,Ning-Hua;  Lau,Clara Bik-San
浏览  |  Adobe PDF(2369Kb)  |  收藏  |  浏览/下载：203/53  |  提交时间：2016/01/19
Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry 期刊论文
FUNGAL DIVERSITY, 2013, 卷号: 62, 期号: 1, 页码: 1-40
作者:  De Silva, Dilani D.;  Rapior, Sylvie;  Sudarman, Enge;  Stadler, Marc;  Xu, Jianchu;  Alias, S. Aisyah;  Hyde, Kevin D.
Adobe PDF(1764Kb)  |  收藏  |  浏览/下载：560/165  |  提交时间：2014/01/13
Medicinal Mushrooms  Anti-oxidant  Anti-tumor  Anti-hiv  Anti-microbial  Anti-viral  Hypocholesterolemic  Anti-diabetic  Anti-alzheimer  Anti-malarial  Food Supplements  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
浏览  |  Adobe PDF(6299Kb)  |  收藏  |  浏览/下载：264/43  |  提交时间：2015/05/14
One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.  
Salinity-induced changes in protein expression in the halophytic plant Nitraria sphaerocarpa 期刊论文
JOURNAL OF PROTEOMICS, 2012, 卷号: 75, 期号: 17, 页码: 5226-5243
作者:  Chen, Jinhui;  Cheng, Tielong;  Wang, Pengkai;  Liu, Weidong;  Xiao, Jiao;  Yang, Yunqiang;  Hu, Xiangyang;  Jiang, Zeping;  Zhang, Shougong;  Shi, Jisen
Adobe PDF(2755Kb)  |  收藏  |  浏览/下载：679/280  |  提交时间：2012/11/30
Comparative Proteomics  Salinity Stress  Nitraria Sphaerocarpa  Cell Suspension  
Clusters of Sudden Unexplained Death Associated with the Mushroom, Trogia venenata, in Rural Yunnan Province, China 期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 5, 页码: e35894
作者:  Shi, Guo-Qing;  Huang, Wen-Li;  Zhang, Jian;  Zhao, Hong;  Shen, Tao;  Fontaine, Robert E.;  Yang, Lin;  Zhao, Su;  Lu, Bu-Lai;  Wang, Yue-Bing;  Ma, Lin;  Li, Zhao-Xiang;  Gao, Yang;  Yang, Zhu-Liang;  Zeng, Guang
浏览  |  Adobe PDF(522Kb)  |  收藏  |  浏览/下载：244/51  |  提交时间：2014/04/02
Electrocardiographic Leads  Syndrome Survivors  Brugada-syndrome  Management  Poisonings  Sleep