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Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry
De Silva, Dilani D.1,2,3,4,5; Rapior, Sylvie6; Sudarman, Enge7; Stadler, Marc7; Xu, Jianchu1,2; Alias, S. Aisyah8; Hyde, Kevin D.1,2,3,4
Corresponding AuthorXu,JC (reprint author),Chinese Acad Sci,Key Lab Plant Biodivers & Biogeog East Asia KLPB,Kunming Inst Bot,Kunming 650201,Yunnan,Peoples R China.,j.c.xu@cgiar.org ; kdhyde3@gmail.com
2013-09-01
Source PublicationFUNGAL DIVERSITY
ISSN1560-2745
Volume62Issue:1Pages:1-40
AbstractExploration of natural sources for novel bioactive compounds has been an emerging field of medicine over the past decades, providing drugs or lead compounds of considerable therapeutic potential. This research has provided exciting evidence on the isolation of microbe-derived metabolites having prospective biological activities. Mushrooms have been valued as traditional sources of natural bioactive compounds for many centuries and have been targeted as promising therapeutic agents. Many novel biologically active compounds have been reported as a result of research on medicinal mushrooms. In this review, we compile the information on bioactive structure-elucidated metabolites from macrofungi discovered over the last decade and highlight their unique chemical diversity and potential benefits to novel drug discovery. The main emphasis is on their anti-Alzheimer, anti-diabetic, anti-malarial, anti-microbial, anti-oxidant, anti-tumor, anti-viral and hypocholesterolemic activities which are important medicinal targets in terms of drug discovery today. Moreover, the reader's attention is brought to focus on mushroom products and food supplements available in the market with claimed biological activities and potential human health benefits.
KeywordMedicinal Mushrooms Anti-oxidant Anti-tumor Anti-hiv Anti-microbial Anti-viral Hypocholesterolemic Anti-diabetic Anti-alzheimer Anti-malarial Food Supplements
Subject AreaMycology
Indexed BySCI
Language英语
WOS Research AreaMycology
WOS SubjectMycology
WOS IDWOS:000326929100001
Citation statistics
Cited Times:108[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/17433
Collection资源植物与生物技术所级重点实验室
Affiliation1.Chinese Acad Sci, Key Lab Plant Biodivers & Biogeog East Asia KLPB, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
2.East Asia Node, World Agroforestry Ctr, Beijing, Peoples R China
3.Mae Fah Luang Univ, Inst Excellence Fungal Res, Chiang Rai 57100, Thailand
4.Mae Fah Luang Univ, Sch Sci, Chiang Rai 57100, Thailand
5.Univ Peradeniya, Dept Bot, Fac Sci, Peradeniya 20500, Sri Lanka
6.Univ Montpellier I, Lab Bot Phytochem & Mycol, Fac Pharm, UMR 5175,CEFE, F-34093 Montpellier 5, France
7.Helmhotz Ctr Infect Res, Dept Microbial Drugs, Braunschweig, Germany
8.Univ Malaya, Inst Ocean & Earth Sci, Kuala Lumpur 50603, Malaysia
Recommended Citation
GB/T 7714
De Silva, Dilani D.,Rapior, Sylvie,Sudarman, Enge,et al. Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry[J]. FUNGAL DIVERSITY,2013,62(1):1-40.
APA De Silva, Dilani D..,Rapior, Sylvie.,Sudarman, Enge.,Stadler, Marc.,Xu, Jianchu.,...&Hyde, Kevin D..(2013).Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry.FUNGAL DIVERSITY,62(1),1-40.
MLA De Silva, Dilani D.,et al."Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry".FUNGAL DIVERSITY 62.1(2013):1-40.
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