Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry
De Silva, Dilani D.1,2,3,4,5; Rapior, Sylvie6; Sudarman, Enge7; Stadler, Marc7; Xu, Jianchu1,2; Alias, S. Aisyah8; Hyde, Kevin D.1,2,3,4
2013-09-01
发表期刊FUNGAL DIVERSITY
ISSN1560-2745
卷号62期号:1页码:1-40
摘要Exploration of natural sources for novel bioactive compounds has been an emerging field of medicine over the past decades, providing drugs or lead compounds of considerable therapeutic potential. This research has provided exciting evidence on the isolation of microbe-derived metabolites having prospective biological activities. Mushrooms have been valued as traditional sources of natural bioactive compounds for many centuries and have been targeted as promising therapeutic agents. Many novel biologically active compounds have been reported as a result of research on medicinal mushrooms. In this review, we compile the information on bioactive structure-elucidated metabolites from macrofungi discovered over the last decade and highlight their unique chemical diversity and potential benefits to novel drug discovery. The main emphasis is on their anti-Alzheimer, anti-diabetic, anti-malarial, anti-microbial, anti-oxidant, anti-tumor, anti-viral and hypocholesterolemic activities which are important medicinal targets in terms of drug discovery today. Moreover, the reader's attention is brought to focus on mushroom products and food supplements available in the market with claimed biological activities and potential human health benefits.
关键词Medicinal Mushrooms Anti-oxidant Anti-tumor Anti-hiv Anti-microbial Anti-viral Hypocholesterolemic Anti-diabetic Anti-alzheimer Anti-malarial Food Supplements
资助信息French-Thai cooperation PHC SIAM [1551, 25587RA];Mae Fah Luang University [MFU/54 1 01 02 00 48];project "Value added products from basidiomycetes: Putting Thailand's biodiversity to use" [BRN049/2553];National Research Council of Thailand (NRCT) [NRCT/55201020007];Thailand Research Fund [BRG 5580009];University Malaya [CG037-2013, RG203-12SUS]
收录类别SCI
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/17433
专题资源植物与生物技术所级重点实验室
作者单位1.Chinese Acad Sci, Key Lab Plant Biodivers & Biogeog East Asia KLPB, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
2.East Asia Node, World Agroforestry Ctr, Beijing, Peoples R China
3.Mae Fah Luang Univ, Inst Excellence Fungal Res, Chiang Rai 57100, Thailand
4.Mae Fah Luang Univ, Sch Sci, Chiang Rai 57100, Thailand
5.Univ Peradeniya, Dept Bot, Fac Sci, Peradeniya 20500, Sri Lanka
6.Univ Montpellier I, Lab Bot Phytochem & Mycol, Fac Pharm, UMR 5175,CEFE, F-34093 Montpellier 5, France
7.Helmhotz Ctr Infect Res, Dept Microbial Drugs, Braunschweig, Germany
8.Univ Malaya, Inst Ocean & Earth Sci, Kuala Lumpur 50603, Malaysia
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De Silva, Dilani D.,Rapior, Sylvie,Sudarman, Enge,et al. Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry[J]. FUNGAL DIVERSITY,2013,62(1):1-40.
APA De Silva, Dilani D..,Rapior, Sylvie.,Sudarman, Enge.,Stadler, Marc.,Xu, Jianchu.,...&Hyde, Kevin D..(2013).Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry.FUNGAL DIVERSITY,62(1),1-40.
MLA De Silva, Dilani D.,et al."Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry".FUNGAL DIVERSITY 62.1(2013):1-40.
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