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题名: Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry
作者: De Silva, Dilani D.1, 2, 3, 4, 5; Rapior, Sylvie6; Sudarman, Enge7; Stadler, Marc7; null(许建初)1, 2; Alias, S. Aisyah8; Hyde, Kevin D.1, 2, 3, 4
刊名: FUNGAL DIVERSITY
关键词: Medicinal mushrooms ; Anti-oxidant ; Anti-tumor ; Anti-HIV ; Anti-microbial ; Anti-viral ; Hypocholesterolemic ; Anti-diabetic ; Anti-Alzheimer ; Anti-malarial ; Food supplements
英文摘要: Exploration of natural sources for novel bioactive compounds has been an emerging field of medicine over the past decades, providing drugs or lead compounds of considerable therapeutic potential. This research has provided exciting evidence on the isolation of microbe-derived metabolites having prospective biological activities. Mushrooms have been valued as traditional sources of natural bioactive compounds for many centuries and have been targeted as promising therapeutic agents. Many novel biologically active compounds have been reported as a result of research on medicinal mushrooms. In this review, we compile the information on bioactive structure-elucidated metabolites from macrofungi discovered over the last decade and highlight their unique chemical diversity and potential benefits to novel drug discovery. The main emphasis is on their anti-Alzheimer, anti-diabetic, anti-malarial, anti-microbial, anti-oxidant, anti-tumor, anti-viral and hypocholesterolemic activities which are important medicinal targets in terms of drug discovery today. Moreover, the reader's attention is brought to focus on mushroom products and food supplements available in the market with claimed biological activities and potential human health benefits.
出版日期: 2013-09-01
卷号: 62, 期号:1, 页码:1-40
语种: 英语
收录类别: SCI
学科分类: Mycology
ISSN号: 1560-2745
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/17433
Appears in Collections:资源植物与生物技术所级重点实验室_期刊论文

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作者单位: 1.Chinese Acad Sci, Key Lab Plant Biodivers & Biogeog East Asia KLPB, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
2.East Asia Node, World Agroforestry Ctr, Beijing, Peoples R China
3.Mae Fah Luang Univ, Inst Excellence Fungal Res, Chiang Rai 57100, Thailand
4.Mae Fah Luang Univ, Sch Sci, Chiang Rai 57100, Thailand
5.Univ Peradeniya, Dept Bot, Fac Sci, Peradeniya 20500, Sri Lanka
6.Univ Montpellier I, Lab Bot Phytochem & Mycol, Fac Pharm, UMR 5175,CEFE, F-34093 Montpellier 5, France
7.Helmhotz Ctr Infect Res, Dept Microbial Drugs, Braunschweig, Germany
8.Univ Malaya, Inst Ocean & Earth Sci, Kuala Lumpur 50603, Malaysia

Recommended Citation:
De Silva,Dilani D.;Rapior,Sylvie;Sudarman,Enge;Stadler,Marc;Xu,Jianchu;Alias,S. Aisyah;Hyde,Kevin D..Bioactive metabolites from macrofungi: ethnopharmacology, biological activities and chemistry,FUNGAL DIVERSITY,2013,62(1):1-40
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