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Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
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2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Dopamine derivatives from the insect Polyrhachis dives as inhibitors of ROCK1/2 and stimulators of neural stem cell proliferation 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 46, 页码: 8852-8857
作者:  Tang, Jian-Jun ab;  Zhang, Li;  Jiang, Li-Ping;  Di, Lei;  Yan, Yong-Ming;  Tu, Zheng-Chao;  Yang, Cui-Ping;  Zuo, Zhi-Li;  Hou, Bo;  Xia, Hou-Lin;  Chen, Yong-Bin;  Cheng, Yong-Xian;  Tu,ZC (reprint author),Chinese Acad Sci,Guangzhou Inst Biomed & Hlth,Key Lab Regenerat Biol,Guangzhou 510530,Guangdong,Peoples R China.;  tu_zhengchao@gibh.ac.cn;  ybchen@mail.kiz.ac.cn;  yxcheng@mail.kib.ac.cn
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Polyrhachis Dives  Dopamine Derivative  Rock1/2 Inhibitors  Nscs  
Characterization and biological evaluation of six new dimeric lignans with an unusual alpha,beta-unsaturated ketone motif from Zanthoxylum simulans 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 19, 页码: 4667-4671
作者:  Wang, Jun-Feng;  Deng, Yi-Hui;  Yang, Sheng-Hui;  Liu, Yan-Qun;  Wang, Yue-Hu;  Pan, Wei-Wei;  Zhou, Xiao-Jiang;  Zhou,XJ (reprint author),Hunan Univ Chinese Med,Coll Pharm,Changsha 410208,Hunan,Peoples R China.;  gale9888@163.com
Adobe PDF(1369Kb)  |  收藏  |  浏览/下载:222/41  |  提交时间:2014/11/25
Zanthoxylum Simulans  Dimeric Lignans  Synovial Cells  Splenocytes  
Alstolactines A-C, novel monoterpenoid indole alkaloids from Alstonia scholaris 期刊论文
TETRAHEDRON LETTERS, 2014, 卷号: 55, 期号: 33, 页码: 4593-4596
作者:  Yang, Xing-Wei;  Qin, Xu-Jie;  Zhao, Yun-Li;  Lunga, Paul K.;  Li, Xiao-Nian;  Jiang, Shi-Zhi;  Cheng, Gui-Guang;  Liu, Ya-Ping;  Luo, Xiao-Dong;  Liu, YP (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China.;  xdluo@mail.kib.ac.cn;  liuyaping@mail.kib.ac.cn
Adobe PDF(726Kb)  |  收藏  |  浏览/下载:239/74  |  提交时间:2014/10/11
Indole Alkaloid  Alstonia Scholaris  Alstolactines A-c  Absolute Configuration  
Chemical and Toxicological Investigations of a Previously Unknown Poisonous European Mushroom Tricholoma terreum 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2014, 卷号: 20, 期号: 23, 页码: 7001-7009
作者:  Yin, Xia;  Feng, Tao;  Shang, Jian-Hua;  Zhao, Yun-Li;  Wang, Fang;  Li, Zheng-Hui;  Dong, Ze-Jun;  Luo, Xiao-Dong;  Liu, Ji-Kai;  Liu,JK (reprint author),Chinese Acad Sci,State Key Lab Phytochem & Plant Resources West Ch,Kunming Inst Bot,Kunming 650201,Peoples R China.;  jkliu@mail.kib.ac.cn
Adobe PDF(936Kb)  |  收藏  |  浏览/下载:658/80  |  提交时间:2014/07/28
Enzymes  Natural Products  Nmr Spectroscopy  Structure Elucidation  X-ray Diffraction  
Synthesis and evaluation of immunostimulant plasmalogen lysophosphatidylethanolamine and analogues for natural killer T cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 11, 页码: 2966-2973
作者:  Ni, Guanghui;  Li, Zhiyuan;  Liang, Kangjiang;  Wu, Ting;  De Libero, Gennaro;  Xia, Chengfeng
Adobe PDF(861Kb)  |  收藏  |  浏览/下载:241/67  |  提交时间:2014/06/23
Nkt Cells  Antigen  Lysophospholipids  Sar  
Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 8, 页码: 1884-1888
作者:  Yan, Chen;  Huang, Li;  Liu, Hong-Chun;  Chen, Duo-Zhi;  Liu, Hai-Yang;  Li, Xiao-Hui;  Zhang, Yu;  Geng, Mei-Yu;  Chen, Quan;  Hao, Xiao-Jiang
Adobe PDF(1562Kb)  |  收藏  |  浏览/下载:297/45  |  提交时间:2014/06/23
Spiramine Derivative  Bax(-/-)/bak(-/-) Cells  Alpha  Apoptosis  Beta-unsaturated Ketone  Cytotoxicity  
Characterization of Diterpenoid Glucosides in Roasted Puer Coffee Beans 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 卷号: 62, 期号: 12, 页码: 2631-2637
作者:  Shu, Yi;  Liu, Jie-Qing;  Peng, Xing-Rong;  Wan, Luo-Sheng;  Zhou, Lin;  Zhang, Tao;  Qiu, Ming-hua
Adobe PDF(288Kb)  |  收藏  |  浏览/下载:380/82  |  提交时间:2014/05/16
Coffea Arabica Var. Yunnanensis  Roasted Coffee Beans  Diterpenoids  Structural Elucidation  Cytotoxicities  
Induced Furoeudesmanes: A Defense Mechanism Against Stress in Laggera pterodonta, a Chinese Herbal Plant 期刊论文
ORGANIC LETTERS, 2013, 卷号: 15, 期号: 19, 页码: 4940-4943
作者:  Liu, Ya-Ping;  Lai, Ren;  Yao, Yong-Gang;  Zhang, Zhong-Kai;  Pu, En-Tang;  Cai, Xiang-Hai;  Luo, Xiao-Dong
Adobe PDF(230Kb)  |  收藏  |  浏览/下载:614/62  |  提交时间:2014/01/13
Resistance  Responses  
Astins K-P, six new chlorinated cyclopentapeptides from Aster tataricus 期刊论文
TETRAHEDRON, 2013, 卷号: 69, 期号: 37, 页码: 7964-7969
作者:  Xu, Hui-Min;  Zeng, Guang-Zhi;  Zhou, Wen-Bing;  He, Wen-Jun;  Tan, Ning-Hua
浏览  |  Adobe PDF(425Kb)  |  收藏  |  浏览/下载:563/91  |  提交时间:2013/10/16
Aster Tataricus  Cyclopentapeptides  Compositae  Astins K-p  Cytotoxicity