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Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 8
作者:  Huang, Jian-Ping;  Fang, Chengli;  Ma, Xiaoyan;  Wang, Li;  Yang, Jing;  Luo, Jianying;  Yan, Yijun;  Zhang, Yu;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(1048Kb)  |  收藏  |  浏览/下载：232/57  |  提交时间：2019/10/28
Structural Revision of Macropodumine A and Structure of 2-Deoxymacropodumine A, Daphniphyllum Alkaloids with 11-Membered Macrolactone Rings 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 3, 页码: 427-430
作者:  Zhang, Jiahui;  Cao, Pei;  Ma, Yuanliang;  Fang, Xin;  Yang, Jing;  Zhang, Yu;  Chen, Duozhi;  Gu, Yucheng;  Di, Yingtong;  Hao, Xiaojiang
浏览  |  Adobe PDF(1044Kb)  |  收藏  |  浏览/下载：223/72  |  提交时间：2019/07/29
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：331/41  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Two new kaurane-type diterpenoids from Wedelia chinensis (Osbeck.) Merr 期刊论文
NATURAL PRODUCT RESEARCH, 2017, 卷号: 31, 期号: 21, 页码: 2531-2536
作者:  Cai, Cancan;  Zhang, Yu;  Yang, Dongqiong;  Hao, Xiaojiang;  Li, Shunlin
浏览  |  Adobe PDF(982Kb)  |  收藏  |  浏览/下载：214/72  |  提交时间：2017/10/23
Wedelia Chinensis  Kauranetype Diterpenoids  Antibacterial Activity  
Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata 期刊论文
PHYTOCHEMISTRY LETTERS, 2016, 卷号: 18, 期号: 1, 页码: 176-179
作者:  Yuan, Wen-Juan;  Yang, Guo-Ping;  Zhang, Jia-Hui;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Di, Ying-Tong;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(558Kb)  |  收藏  |  浏览/下载：507/162  |  提交时间：2017/02/14
Euphorbiaceae  Euphorbia Ebracteolata  Diterpenes  Ebracteolatas A-c  Cytotoxic Activity  
16-nor Limonoids from Harrisonia perforata as promising selective 11 beta-HSD1 inhibitors 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 1
作者:  Xiao-HuiYan;  Yi, Ping;  Cao, Pei;  Yang, Shi-Ying;  Fang, Xin;  Zhang, Yu;  Wu, Bin;  Leng, Ying;  Di, Ying-Tong;  Lv, Yang;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1151Kb)  |  收藏  |  浏览/下载：353/57  |  提交时间：2017/01/05
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin;  Zhang, Yu;  Yu, Lijing;  Hu, Kaifeng;  Zhu, Weiliang;  Tong, Qingchun;  Chen, Kaixian;  Guo, Fujiang;  Huang, Cheng;  Li, Yiming
浏览  |  Adobe PDF(841Kb)  |  收藏  |  浏览/下载：248/98  |  提交时间：2016/08/22
Alternative Binding Site  Bavachinin  Canonical Ligand-binding Pocket  Carbohydrate Metabolism  Lipid Metabolism  Pan-ppar Agonist  Synergistic Effects  
Synthesis, Neuro-protection and Anti-cancer Activities of Simple Isatin Mannich and Schiff Bases 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2016, 卷号: 13, 期号: 5, 页码: 395-400
作者:  Chen, Gang;  Ning, Yang;  Zhao, Wei;  Zhang, Yanqiu;  Zhang, Yu;  Hao, Xiaojiang;  Wang, Ye;  Mu, Shuzhen
浏览  |  Adobe PDF(1361Kb)  |  收藏  |  浏览/下载：263/74  |  提交时间：2016/08/22
Isatin  Mannich Base  Schiff Base  Synthesis  Neuro-protection  Anti-tumor  
Alstoscholarisines F and G, two unusual monoterpenoid indole alkaloids from the leaves of Alstonia scholaris 期刊论文
TETRAHEDRON LETTERS, 2015, 卷号: 56, 期号: 48, 页码: 6715-6718
作者:  Yang,Xing-Wei;  Song,Chang-Wei;  Zhang,Yu;  Khan,Afsar;  Jiang,Li-Ping;  Chen,Yong-Bin;  Liu,Ya-Ping;  Luo,Xiao-Dong
浏览  |  Adobe PDF(698Kb)  |  收藏  |  浏览/下载：250/64  |  提交时间：2016/01/19
Monoterpenoid Indole Alkaloid  Alstonia Scholaris  Alstoscholarisines f And g  Absolute Configuration  
Theoretical study of regioselectivity in the synthesis of spiro [pyrrolidine-2,3'-oxindole] compounds by [3+2] cycloaddition 期刊论文
RESEARCH ON CHEMICAL INTERMEDIATES, 2015, 卷号: 41, 期号: 7, 页码: 4987-4996
作者:  Chen, Gang;  Yang, Jing;  Gao, Suo;  Zhang, Yu;  Hao, Xiaojiang
Adobe PDF(1404Kb)  |  收藏  |  浏览/下载：158/40  |  提交时间：2015/12/17
Regioselectivity  Theoretical  Spiro-oxindole  [3+2] Cycloaddition