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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
Authors:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
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Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
Authors:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
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Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Chemical Constituents of Primulina eburnea (Gesneriaceae) and Their Cytotoxic Activities 期刊论文
CHEMISTRY & BIODIVERSITY, 2023
Authors:  Yang,Li-Yuan;  Yi,Ping;  Chen,Jun-Lei;  Li,Yu-Huan;  Qiu,Jue-Lin;  Wang,Zhao-Yang;  Fu,Mao;  Yuan,Chun-Mao;  Huang,Lie-Jun;  Hao,Xiao-Jiang;  Gu,Wei
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Primulina eburnea  triterpenes  flavonoids  phenylethanoid glycosides  cytotoxic activity  GLUCOSIDES  LEAVES  CELL  
Three New Constituents with Anti-Inflammatory and Antimicrobial Activities in Vitro from the Roots of Capsicum annuum L. 期刊论文
CHEMISTRY & BIODIVERSITY, 2023, 卷号: 20, 期号: 8
Authors:  Shi,Jiang;  Deng,Lu-Lu;  Li,Jiang;  Wang,Min;  Fan,Yan-Hua;  Pan,Wei-Dong;  Hao,Xiao-Jiang;  Mu,Shu-Zhen
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anti-inflammatory  active constituent  roots of Capsicum annuum L  sesquiterpenes  structural identification  AGRICULTURAL WASTE  SESQUITERPENOIDS  
UPLC-Q-Orbitrap-MS/MS-Guided Isolation of Bioactive Withanolides from the Fruits of Physalis angulata 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 44, 页码: 16581-16592
Authors:  Wang,Peng;  Yang,Xiao-Meng;  Hu,Zhan-Xing;  Li,Ya-Nan;  Yang,Jue;  Hao,Xiao-Jiang;  Yuan,Chun-Mao;  Yi,Ping
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Physalis angulata  rare withanolidederivatives  isolation and identification  anticancer  anti-inflammatory activity  CYTOTOXIC WITHANOLIDES  CONSTITUENTS  PLANTS  L.  
Matrine-Type Alkaloids with Anti-Tomato Spotted Wilt Virus Activity from the Root of Sophora tonkinensis Gagnep. 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 10, 页码: 4394-4407
Authors:  Zhao,Li-Hua;  Hu,Zhan-Xing;  Hao,Xiao-Jiang;  Zhang,Peng;  Zhang,Ji;  An,Qiao;  Wang,Juan;  Yi,Ping;  Yuan,Chun-Mao;  Zhang,Zhong-Kai
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Sophora tonkinensis Gagnep  matrine-type alkaloids  anti-TSWV  LUPIN ALKALOIDS  QUINOLIZIDINE ALKALOIDS  SEEDS  
Artemeriopolides A-D, two types of sesquiterpenoid dimers with rare carbon skeletons from Artemisia eriopoda and their antihepatoma cytotoxicity 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 11, 页码: 2635-2641
Authors:  He,Xiao-Feng;  Li,Qi-Hao;  Li,Tian-Ze;  Ma,Yun-Bao;  Dong,Wei;  Yang,Ke-Xin;  Geng,Chang-An;  Zhang,Hao-Wei;  Wang,Yuan;  Chen,Ji-Jun
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Constituents from Zanthoxylum dimorphophyllum and their chemotaxonomic significance 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2023, 卷号: 108, 页码: 104640
Authors:  Wang,Zhaoyang;  Yuan,Chunmao;  Chen,Junlei;  Li,Yuhuan;  Wei,Yinghuan;  Li,Huanyang;  Qiu,Juelin;  Huang,Liejun;  Hu,Zhanxing;  Hao,Xiaojiang;  Gu,Wei
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Chemotaxonomic significance  Zanthoxylum dimorphophyllum  Rutaceae  Coumarins  Lignans  Alkaloids  CHEMICAL-CONSTITUENTS  ANTIINFLAMMATORY CONSTITUENTS  ANTIPLATELET CONSTITUENTS  AERIAL PARTS  ROOT BARK  COUMARINS  DERIVATIVES  
A flavonolignan, flavonoids and alkylamides from the fruits of Zanthoxylum Motuoense Huang 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2023, 卷号: 109, 页码: 104659
Authors:  Wei,Yinghuan;  Chen,Junlei;  Qiu,Juelin;  Wang,Zhaoyang;  Li,Huanyang;  Yang,Jue;  Huang,Liejun;  Yuan,Chunmao;  Hao,Xiaojiang;  Gu,Wei
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Zanthoxylum motuoense Huang  Flavonolignan  Alkylamides  Neuroprotective activity  Chemotaxonomy  ALIPHATIC ACID-AMIDES  
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction 期刊论文
NATURE CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 4, 页码: 468-+
Authors:  Guo,Yingjie;  Zhang,Huan;  Yan,Chen;  Shen,Birong;  Zhang,Yue;  Guo,Xiangyang;  Sun,Sha;  Yu,Fan;  Yan,Jiayun;  Liu,Ronghe;  Zhang,Qianping;  Zhang,Di;  Liu,Haiyang;  Liu,Yang;  Zhang,Yaoyao;  Li,Wenlei;  Qin,Jiangyu;  Lv,He;  Wang,Zhaoxia;  Yuan,Yun;  Yang,Jie-Feng;  Zhong,Ya-Ting;  Gao,Song;  Zhou,Bing;  Liu,Lei;  Kong,Deling;  Hao,Xiaojiang;  Hu,Junjie;  Chen,Quan
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ENDOPLASMIC-RETICULUM  PROVIDE INSIGHT  MITOFUSIN 2  MFN1  DYNAMICS  REQUIRES  DEFECTS  FISSION  CELLS