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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
作者:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  收藏  |  浏览/下载：312/1  |  提交时间：2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
作者:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
Adobe PDF(1611Kb)  |  收藏  |  浏览/下载：134/1  |  提交时间：2017/07/24
Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
New eudesmanolides from Artemisia verlotorum and their potential targets of hepatocellular carcinoma by network pharmacology 期刊论文
FITOTERAPIA, 2023, 卷号: 167, 页码: 105491
作者:  Dong,Wei;  Yang,Ke-Xin;  He,Xiao-Feng;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(10566Kb)  |  收藏  |  浏览/下载：11/7  |  提交时间：2024/07/25
Artemisia verlotorum  Eudesmanolides  Network pharmacology  Molecular docking  Surface Plasmon Resonance  AURORA KINASE  SESQUITERPENOIDS  AURKA  EXPRESSION  
Hepatic RACK1 deletion disturbs lipid and glucose homeostasis independently of insulin resistance 期刊论文
JOURNAL OF ENDOCRINOLOGY, 2022, 卷号: 254, 期号: 3, 页码: 151-165
作者:  Qin, Wanying;  Zhang, Ting;  Ge, Mingxia;  Zhou, Huimin;  Xu, Yuhui;  Mu, Rongfang;  Huang, Chaoguang;  Liu, Daowei;  Huang, Bangrui;  Wang, Qian;  Kong, Qinghua;  Kong, Qingpeng;  Li, Fei;  Xiong, Wenyong
浏览  |  Adobe PDF(9525Kb)  |  收藏  |  浏览/下载：53/11  |  提交时间：2024/04/30
RACK1  bile acid  glucose metabolism  insulin sensitivity  ENDOPLASMIC-RETICULUM STRESS  C-KINASE 1  HEPATOCELLULAR-CARCINOMA  STEROL 12-ALPHA-HYDROXYLASE  DOWN-REGULATION  ER STRESS  KAPPA-B  RECEPTOR  ACTIVATION  GROWTH  
The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 874474
作者:  Arunachalam, Karuppusamy;  Sreeja, Puthanpura Sasidharan;  Yang, Xuefei
浏览  |  Adobe PDF(2493Kb)  |  收藏  |  浏览/下载：12/5  |  提交时间：2024/08/21
reactive oxygen species  oxidative stress  antioxidant  diabetes mellitus  mushroom polysaccharides  AGARICUS-BLAZEI MURILL  GANODERMA-LUCIDUM POLYSACCHARIDES  ACTIVATED SIGNALING PATHWAYS  TYPE-2 DIABETES-MELLITUS  PROTEIN-KINASE-C  MT-ALPHA-GLUCAN  MEDICINAL MUSHROOM  SUBMERGED-CULTURE  PHELLINUS-LINTEUS  STRUCTURAL-CHARACTERIZATION  
Phenolic signals for prehaustorium formation in Striga hermonthica 期刊论文
FRONTIERS IN PLANT SCIENCE, 2022, 卷号: 13, 页码: 1077996
作者:  Aoki, Natsumi;  Cui, Songkui;  Ito, Chiharu;  Kumaishi, Kie;  Kobori, Shungo;  Ichihashi, Yasunori;  Yoshida, Satoko
浏览  |  Adobe PDF(3209Kb)  |  收藏  |  浏览/下载：8/4  |  提交时间：2024/08/21
striga  prehaustorium  phenolics  quinone  parasitic plants  AGROBACTERIUM VIRULENCE GENES  HAUSTORIUM DEVELOPMENT  QUINONE OXIDOREDUCTASE  PARASITIC ANGIOSPERMS  PLANT  MECHANISM  ACTIVATION  KINASE  
Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
作者:  Li,Xu-xia;  Zhang,Peng;  Yang,Yang;  Wang,Jing-jing;  Zheng,Yan-jun;  Tan,Ji-liang;  Liu,Shen-yan;  Yan,Yong-ming;  Zhang,You-yi;  Cheng,Yong-xian;  Yang,Huang-tian
浏览  |  Adobe PDF(4052Kb)  |  收藏  |  浏览/下载：91/1  |  提交时间：2022/04/02
cardiac hypertrophy  pyrazine derivative  QF84139  phenylephrine  transverse aortic constriction  AMPK signaling pathway  PROTEIN-KINASE  MAMMALIAN TARGET  OVERLOAD  METFORMIN  MACROPHAGES  MECHANISMS  MEDICINE  ALPHA  CELLS  MODEL  
Genomic Characterization and Expression Analysis of the SnRK Family Genes in Dendrobium officinale Kimura et Migo (Orchidaceae) 期刊论文
PLANTS-BASEL, 2021, 卷号: 10, 期号: 3, 页码: 479
作者:  Wang,Yue;  Liu,Aizhong
收藏  |  浏览/下载：145/0  |  提交时间：2022/04/02
sucrose non-fermenting1-related protein kinases (SnRKs)  Dendrobium officinale  expression patterns  stress  IMPROVES DROUGHT TOLERANCE  TRITICUM-AESTIVUM L.  PROTEIN-KINASE  WIDE IDENTIFICATION  STRESS TOLERANCE  PLANT-RESPONSE  FRUIT-DEVELOPMENT  SALT STRESS  ARABIDOPSIS  RICE  
High-Throughput In Vitro Gene Expression Profile to Screen of Natural Herbals for Breast Cancer Treatment 期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:  Kui,Ling;  Kong,Qinghua;  Yang,Xiaonan;  Pan,Yunbing;  Xu,Zetan;  Wang,Shouling;  Chen,Jian;  Wei,Kunhua;  Zhou,Xiaolei;  Yang,Xingzhi;  Wu,Tingqin;  Mastan,Anthati;  Liu,Yao;  Miao,Jianhua
收藏  |  浏览/下载：97/0  |  提交时间：2022/04/02
breast cancer  traditional Chinese medicine (TCM)  high-throughput sequencing  transcriptome analysis  WGCNA  COEXPRESSION NETWORK ANALYSIS  IL-17 RECEPTOR  RNA-SEQ  IDENTIFICATION  KINASE  CELLS  TRANSCRIPTOME  INDUCTION  PRODUCTS  PROMOTES  
Bitter Melon and Diabetes Mellitus 期刊论文
FOOD REVIEWS INTERNATIONAL, 2021
作者:  Gao,Ya;  Li,Xian;  Huang,Yanjie;  Chen,Jianchao;  Qiu,Minghua
收藏  |  浏览/下载：87/0  |  提交时间：2022/04/02
Bitter melon  diabetes mellitus  crude extracts  phyto-metabolites  hypoglycemic mechanism  MOMORDICA-CHARANTIA L.  11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1  ALPHA-GLUCOSIDASE INHIBITION  INSULIN-RESISTANCE  ANTIDIABETIC ACTIVITIES  GUT MICROBIOTA  STRUCTURAL-CHARACTERIZATION  PHENOLIC-COMPOUNDS  OXIDATIVE STRESS  PROTEIN-KINASE