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Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
浏览  |  Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：233/58  |  提交时间：2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
浏览  |  Adobe PDF(2607Kb)  |  收藏  |  浏览/下载：266/46  |  提交时间：2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
收藏  |  浏览/下载：187/0  |  提交时间：2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC  
Polysaccharides of Dendrobium officinale Kimura & Migo protect gastric mucosal cell against oxidative damage-induced apoptosis in vitro and in vivo 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2017, 卷号: 208, 页码: 214-224
作者:  Zeng, Qiang;  Ko, Chun-Hay;  Siu, Wing-Sum;  Li, Long-Fei;  Han, Xiao-Qiang;  Yang, Liu;  Lau, Clara Bik-San;  Hu, Jiang-Miao;  Leung, Ping-Chung
Adobe PDF(1075Kb)  |  收藏  |  浏览/下载：246/59  |  提交时间：2017/10/23
Polysaccharides  Dendrobium Officinale Kimura & Migo  Gastric Injury  Oxidative Damage  Apoptosis  
Isocostunolide inhibited glioma stem cell by suppression proliferation and inducing caspase dependent apoptosis 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 页码: 2863-2867
作者:  Dai, Zhi;  Li, Shi-Rong;  Zhu, Pei-Feng;  Liu, Lu;  Wang, Bei;  Liu, Ya-Ping;  Luo, Xiao-Dong;  Zhao, Xu-Dong
浏览  |  Adobe PDF(2209Kb)  |  收藏  |  浏览/下载：274/61  |  提交时间：2017/07/18
Isocostunolide  Glioma Stem Cells  Cell Proliferation  Apoptosis  Colony Formation  
Synthesis and cytotoxic activity of novel tetrahydrobenzodifuran-imidazolium salt derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 8, 页码: 1808-1814
作者:  Zhang, Chao-Bo;  Liu, Yang;  Liu, Zheng-Fen;  Duan, Sheng-Zu;  Li, Min-Yan;  Chen, Wen;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
浏览  |  Adobe PDF(1192Kb)  |  收藏  |  浏览/下载：612/103  |  提交时间：2017/06/30
Tetrahydrobenzodifurans  Imidazolium Salts  Cytotoxic Activity  Cell Cycle  Apoptosis  
A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells 期刊论文
ONCOLOGY REPORTS, 2017, 卷号: 37, 期号: 4, 页码: 2079-2086
作者:  Dai, Xiaoli;  Liu, Jing;  Nian, Yin;  Qiu, Ming-Hua;  Luo, Ying;  Zhang, Jihong
浏览  |  Adobe PDF(1057Kb)  |  收藏  |  浏览/下载：204/44  |  提交时间：2017/06/01
Cimicifuga  Apoptosis  Autophagy  Colon Cancer Cells  
Efficient Semisynthesis of (-)-Pseudoirroratin A from (-)-Flexicaulin A and Assessment of Their Antitumor Activities 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 3, 页码: 372-376
作者:  Guo, Lei;  Tsang, Siu Wai;  Zhang, Tong-Xin;  Liu, Kang-Lun;  Guan, Yi-Fu;  Wang, Bo;  Sun, Han-Dong;  Zhang, Hong-Jie;  Wong, Man Shing
浏览  |  Adobe PDF(1840Kb)  |  收藏  |  浏览/下载：207/40  |  提交时间：2017/05/19
(-)-pseudoirroratin a  (-)-flexicaulin a  Apoptosis  Antitumor Activity  
Melodinine V, an antitumor bisindole alkaloid with selective cytotoxicity from Melodinus henryi 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 20, 页码: 4895-4898
作者:  Liu, Ya-Ping;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Feng, Tao;  Zhao, Yun-Li;  Li, Yan;  Lau, Clara Bik-San;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1084Kb)  |  收藏  |  浏览/下载：226/59  |  提交时间：2017/01/05
Melodinine v  Bisindole  Inhibited Cell Proliferation  Cell Cycle Arrest  Cellular Apoptosis  Ht-29 Cells  
Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 66689-66699
作者:  Zhang, Ruowen;  Che, Xun;  Zhang, Jingjie;  Li, Yang;  Li, Jingxia;  Deng, Xu;  Zhu, Junlan;  Jin, Honglei;  Zhao, Qinshi;  Huang, Chuanshu
Adobe PDF(9106Kb)  |  收藏  |  浏览/下载：187/42  |  提交时间：2017/01/05
Chel a  Human Bladder Cancer  Apoptosis  Phlpp2  C-jun