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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：311/37  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：289/63  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic Streptomyces 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 2, 页码: 177-182
作者:  Zhang, Zhouxin;  Cao, Pei;  Shang, Ning-Ning;  Yang, Jing;  Wang, Li;  Yan, Yijun;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(990Kb)  |  收藏  |  浏览/下载：186/32  |  提交时间：2019/03/18
Anti-hepatitis B virus effects of the traditional Chinese herb Arteinisia capillaris and its active enynes 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 224, 页码: 283-289
作者:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Yang, Jing;  Ma, Yun-Bao;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
收藏  |  浏览/下载：257/0  |  提交时间：2018/09/27
Artemisia capillaris  Enynes  Anti-HBV activity  Structure-activity relationships  
Belamchinanes A-D from Belamcanda chinensis: Triterpenoids with an Unprecedented Carbon Skeleton and Their Activity against Age-Related Renal Fibrosis 期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 17, 页码: 5506-5509
作者:  Song, Ying-Ying;  Miao, Jin-Hua;  Qin, Fu-Ying;  Yan, Yong-Ming;  Yang, Jing;  Qin, Da-Peng;  Hou, Fan-Fan;  Zhou, Li-Li;  Cheng, Yong-Xian
收藏  |  浏览/下载：125/0  |  提交时间：2018/10/22
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
作者:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
收藏  |  浏览/下载：364/0  |  提交时间：2018/11/12
Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization