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Paris Saponin VII Induces Apoptosis and Cell Cycle Arrest in Erythroleukemia Cells by a Mitochondrial Membrane Signaling Pathway 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 4, 页码: 498-507
作者:  Lin,Xin;  Gajendran,Babu;  Varier,Krishnapriya M.;  Liu,Wuling;  Song,Jingrui;  Rao,Qing;  Wang,Chunlin;  Qiu,Jianfei;  Ni,Wei;  Qin,XuJie;  Wen,Min;  Liu,Haiyang;  Li,Yanmei
收藏  |  浏览/下载:72/0  |  提交时间:2022/04/02
Leukemia  Paris Saponin VII  HEL  cell cycle  apoptosis  membrane signaling pathway  
New diterpenoids from the rhizomes of Hedychium forrestii 期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 15, 页码: 2463-2469
作者:  Wang,Wen-Hui;  Gao,Jie-Jie;  Zuo,Xiao-Fei;  Qin,Xu-Jie;  Liu,Hai-Yang;  Zhao,Qing
收藏  |  浏览/下载:50/0  |  提交时间:2022/04/02
Hedychium forrestii  hexanorditerpenoid  hedychins C and D  cytotoxicity  LABDANE-TYPE DITERPENOIDS  CONSTITUENTS  CYTOTOXICITY  CORONARIUM  YUNNANENSE  
AmAT19, an acetyltransferase from Astragalus membranaceus, catalyses specific 6 alpha-OH acetylation for tetracyclic triterpenes and steroids 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 33, 页码: 7186-7189
作者:  Wang,Linlin;  Chen,Kuan;  Wang,Zilong;  Yi,Yang;  Zhang,Meng;  Hasan,Aobulikasimu;  Kuang,Yi;  Shaker,Sharpkate;  Yu,Rong;  Wang,Haotian;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
收藏  |  浏览/下载:61/0  |  提交时间:2022/04/02
ACYLATION  ACYLTRANSFERASE  CYCLOASTRAGENOL  BAHD  
Robustadial A and B from Eucalyptus globulus Labill. and their anticancer activity as selective tyrosyl-DNA phosphodiesterase 2 inhibitors 期刊论文
PHYTOTHERAPY RESEARCH, 2021, 卷号: 35, 期号: 9, 页码: 5282-5289
作者:  Zhang,Yu;  He,Xiao-Zhi;  Yang,Hao;  Liu,Hai-Yang;  An,Lin-Kun
收藏  |  浏览/下载:66/0  |  提交时间:2022/04/02
anticancer  Eucalyptus globulus Labill  inhibitors  synergistic effect  tyrosyl-DNA phosphodiesterase  SMALL-MOLECULE INHIBITORS  1 TDP1  
Acylphloroglucinols with acetylcholinesterase inhibitory effects from the fruits of Eucalyptus robusta (vol 103, 104127, 2020) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104579
作者:  Liu,Hui;  He,Xiao-Zhi;  Feng,Mi-Yan;  Zeng,Yuan;  Rauwolf,Tyler J.;  Shao,Li-Dong;  Ni,Wei;  Yan,Hui;  Porco,John A.,Jr.;  Hao,Xiao-Jiang;  Qin,Xu-Jie;  Liu,Hai-Yang
收藏  |  浏览/下载:60/0  |  提交时间:2022/04/02
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
作者:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
Adobe PDF(8744Kb)  |  收藏  |  浏览/下载:97/38  |  提交时间:2022/04/02
Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
Molecular networking uncovers steroidal saponins of Paris tengchongensis (vol 145, 104629, 2020) 期刊论文
FITOTERAPIA, 2021, 卷号: 150, 页码: 104830
作者:  Wang,Jie;  Li,Dan;  Ni,Wei;  Qin,Xu-Jie;  Liu,Hui;  Yu,Ling-Ling;  Qiao,Xue;  Ji,Yun-Heng;  He,Li;  Nian,Si-Hui;  Liu,Hai-Yang
Adobe PDF(2144Kb)  |  收藏  |  浏览/下载:84/29  |  提交时间:2022/04/02
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
作者:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
Adobe PDF(2105Kb)  |  收藏  |  浏览/下载:97/43  |  提交时间:2022/04/02
Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA  
Phytochemicals from the Leaves of Cyclocarya paliurus and their 11 beta-HSD1 Enzyme Inhibitory Effects 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 卷号: 18, 期号: 1
作者:  Yan,Huan;  Li,Xiang;  Ni,Wei;  Zhao,Qing;  Leng,Ying;  Liu,Hai-Yang
Adobe PDF(1714Kb)  |  收藏  |  浏览/下载:80/27  |  提交时间:2022/04/02
Cyclocarya paliurus  dammarane-type triterpenoid saponins  11β  -HSD1 enzyme  inhibitory activity  ANTIOXIDANT ACTIVITIES  CHEMICAL-CONSTITUENTS  DEHYDROGENASE TYPE-1  TRITERPENOIDS  POLYSACCHARIDE  SAPONINS  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
Adobe PDF(2630Kb)  |  收藏  |  浏览/下载:151/82  |  提交时间:2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2