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Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction 期刊论文
NATURE CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 4, 页码: 468-+
作者:  Guo,Yingjie;  Zhang,Huan;  Yan,Chen;  Shen,Birong;  Zhang,Yue;  Guo,Xiangyang;  Sun,Sha;  Yu,Fan;  Yan,Jiayun;  Liu,Ronghe;  Zhang,Qianping;  Zhang,Di;  Liu,Haiyang;  Liu,Yang;  Zhang,Yaoyao;  Li,Wenlei;  Qin,Jiangyu;  Lv,He;  Wang,Zhaoxia;  Yuan,Yun;  Yang,Jie-Feng;  Zhong,Ya-Ting;  Gao,Song;  Zhou,Bing;  Liu,Lei;  Kong,Deling;  Hao,Xiaojiang;  Hu,Junjie;  Chen,Quan
浏览  |  Adobe PDF(25423Kb)  |  收藏  |  浏览/下载：31/13  |  提交时间：2024/07/25
ENDOPLASMIC-RETICULUM  PROVIDE INSIGHT  MITOFUSIN 2  MFN1  DYNAMICS  REQUIRES  DEFECTS  FISSION  CELLS  
Three new diterpenoids fromEuphorbia peplus 期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 21, 页码: 3901-3907
作者:  Chen,Yan-Ni;  Lu,Qing-Yun;  Li,Dong-Mei;  Li,Ying-Yao;  Pu,Xue-Xue;  Li,Bo-Ting;  Tang,Xiao-Han;  Tang,Hong-Yu;  Liu,Shuai;  Yang,Lei;  Zhang,Yu;  Di,Ying-Tong;  Fang,Xin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(374Kb)  |  收藏  |  浏览/下载：143/40  |  提交时间：2022/04/02
Euphorbiaceae  Euphorbia peplus  ent-abietane diterpenoids  paralianone diterpenoids  EUPHORBIA-PEPLUS  STEMS  
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2579Kb)  |  收藏  |  浏览/下载：191/62  |  提交时间：2023/09/08
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 2, 页码: 262-267
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
收藏  |  浏览/下载：85/0  |  提交时间：2022/04/02
AMYLOID PRECURSOR PROTEIN  INSULIN-DEGRADING ENZYME  BETA-PROTEIN  GEMFIBROZIL  PREVENTION  SECRETASE  ADAM10  MEN  
Synthesis and PDE-10 Inhibition of 3-substituted Phenylimino-indolin-2-ones 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 卷号: 126, 页码: 34-34
作者:  Wu, Ya;  Lin, Zhiwei;  Bai, Yun;  Zhang, Yu;  Cai, Qing;  Mu, Shuzhen;  Han, Weiwei;  Hao, Xiaojiang;  Chen, Gang
收藏  |  浏览/下载：219/0  |  提交时间：2020/03/24
Three new diterpenoids fromEuphorbia peplus 期刊论文
NATURAL PRODUCT RESEARCH, 2020
作者:  Chen, Yan-Ni;  Lu, Qing-Yun;  Li, Dong-Mei;  Li, Ying-Yao;  Pu, Xue-Xue;  Li, Bo-Ting;  Tang, Xiao-Han;  Tang, Hong-Yu;  Liu, Shuai;  Yang, Lei;  Zhang, Yu;  Di, Ying-Tong;  Fang, Xin;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1031Kb)  |  收藏  |  浏览/下载：233/92  |  提交时间：2021/01/05
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：364/54  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Synthesis of 4-ethyl-5-methyl-5,6-dihydrophenanthridine-8,9-diol as the key intermediate of potent agonists of the Wnt signalling pathway 期刊论文
JOURNAL OF CHEMICAL RESEARCH, 2015, 期号: 4, 页码: 247-250
作者:  Jing, Chen-xu;  Cai, Jie-yun;  Zhang, Yu;  Chen, Duo-zhi;  Hao, Xiao-jiang
浏览  |  Adobe PDF(418Kb)  |  收藏  |  浏览/下载：173/58  |  提交时间：2016/01/19
Phenanthridin  Palladium Catalyst  Aryl-aryl Coupling  N-aryl Coupling  
Limonoids from Aphanamixis polystachya and Their Antifeedant Activity 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2014, 卷号: 77, 期号: 3, 页码: 472-482
作者:  Cai, Jie-Yun;  Chen, Duo-Zhi;  Luo, Shi-Hong;  Kong, Ning-Chuan;  Zhang, Yu;  Di, Ying-Tong;  Zhang, Qiang;  Hua, Juan;  Jing, Shu-Xi;  Li, Shun-Lin;  Li, Sheng-Hong;  Hao, Xiao-Jiang;  He, Hong-Ping
浏览  |  Adobe PDF(477Kb)  |  收藏  |  浏览/下载：445/132  |  提交时间：2014/05/16
Biological-activities  Cipadessa-baccifera  Meliaceae  Tetranortriterpenoids  Sesquiterpenes  Triterpenoids  Prieurianin  Derivatives  Chemistry  Mangrove  
Evaluation of anti-HCV activity and SAR study of (+)-lycoricidine through targeting of host heat-stress cognate 70 (Hsc70) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 9, 页码: 2679-2682
作者:  Chen, Duo-Zhi;  Jiang, Jian-Dong;  Zhang, Ke-Qing;  He, Hong-Ping;  Di, Ying-Tong;  Zhang, Yu;  Cai, Jie-Yun;  Wang, Lei;  Li, Shun-Lin;  Yi, Ping;  Peng, Zong-Gen;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(555Kb)  |  收藏  |  浏览/下载：538/114  |  提交时间：2013/06/08
(+)-lycoricidine  Heat-stress Cognate 70 (Hsc70)  Down-regulators  Structure-activity Relationship (Sar)  Anti-hcv Activity