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The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
Authors:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
Favorite  |  View/Download:363/0  |  Submit date:2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2015, 卷号: 7, 期号: 5, 页码: 561-570
Authors:  Chen, Duozhi;  Cai, Jieyun;  Yin, Junlin;  Jiang, Jiandong;  Jing, Chenxu;  Zhu, Yanping;  Cheng, Junjun;  Di, Yingtong;  Zhang, Yu;  Cao, Mingming;  Li, Shunlin;  Peng, Zonggen;  Hao, Xiaojiang;  Hao,XJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  haoxj@mail.kib.ac.cn
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Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum 期刊论文
PHYTOCHEMISTRY, 2013, 卷号: 96, 页码: 360-369
Authors:  Cheng, Yuan-Yuan;  Chen, Huan;  He, Hong-Ping;  Zhang, Yu;  Li, Shi-Fei;  Tang, Gui-Hua;  Guo, Ling-Li;  Yang, Wei;  Zhu, Feng;  Zheng, Yong-Tang;  Li, Shun-Lin;  Hao, Xiao-Jiang
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Trigonostemon Thyrsoideum  Euphorbiaceae  Daphnane Diterpenoids  Trigothysoids A-p  Anti-hiv-1  
A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 期号: SI, 页码: 485-494
Authors:  Liu, Jinhua;  Mu, Chenglong;  Yue, Wen;  Li, Jie;  Ma, Biao;  Zhao, Lixia;  Liu, Lei;  Chen, Quan;  Yan, Chen;  Liu, Haiyang;  Hao, Xiaojiang;  Zhu, Yushan
View  |  Adobe PDF(2679Kb)  |  Favorite  |  View/Download:212/36  |  Submit date:2013/10/16
Thioredoxin Reductase  Bim  Ros  Apoptosis  Cancer  
Natural Diterpenoid Compound Elevates Expression of Bim Protein, Which Interacts with Antiapoptotic Protein Bcl-2, Converting It to Proapoptotic Bax-like Molecule 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 卷号: 287, 期号: 2, 页码: 1054-1065
Authors:  Zhao, Lixia;  He, Feng;  Liu, Haiyang;  Zhu, Yushan;  Tian, Weili;  Gao, Ping;  He, Hongping;  Yue, Wen;  Lei, Xiaobo;  Ni, Biyun;  Wang, Xiaohui;  Jin, Haijing;  Hao, Xiaojiang;  Lin, Jialing;  Chen, Quan
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Phragmalin- and Mexicanolide-Type Limonoids from the Leaves of Trichilia connaroides 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2011, 卷号: 74, 期号: 2, 页码: 152-157
Authors:  Zhang, Qiang;  Di, Ying-Tong;  He, Hong-Ping;  Fang, Xin;  Chen, Dong-Lin;  Yan, Xiao-Hui;  Zhu, Feng;  Yang, Ting-Quan;  Liu, Ling-Li;  Hao, Xiao-Jiang
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Carbon Skeleton  Tetranortriterpenoids  Extractives  Meliaceae  
Aminocadambines A and B, two novel indole alkaloids from Neolamarckia cadamba 期刊论文
TETRAHEDRON LETTERS, 2010, 卷号: 51, 期号: 43, 页码: 5670-5673
Authors:  Liu, Ling-Li;  Di, Ying-Tong;  Zhang, Qiang;  Fang, Xin;  Zhu, Feng;  Chen, Dong-Lin;  Hao, Xiao-Jiang;  He, Hong-Ping
Adobe PDF(493Kb)  |  Favorite  |  View/Download:336/169  |  Submit date:2012/03/21
Neolamarckia Cadamba  Indole Alkaloids  Structure Elucidation  
Cytotoxicity of cardenolides and cardenolide glycosides from Asclepias curassavica 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 卷号: 19, 期号: 7, 页码: 1956-1959
Authors:  Li, Jun-Zhu;  Qing, Chen;  Chen, Chang-Xiang;  Hao, Xiao-Jiang;  Liu, Hai-Yang
Adobe PDF(320Kb)  |  Favorite  |  View/Download:917/238  |  Submit date:2011/12/19
Asclepias Curassavica  Asclepiadaceae  Cardenolide  Cardenolide Glycoside  Cytotoxicity  
Six new C(21) steroidal glycosides from Asclepias curassavica L. 期刊论文
STEROIDS, 2008, 卷号: 73, 期号: 6, 页码: 594-600
Authors:  Li, Jun-Zhu;  Liu, Hai-Yang;  Lin, Yi-Ju;  Hao, Xiao-Jiang;  Ni, Wei;  Chen, Chang-Xiang
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Asclepias Curassavica  Asclepiadaceae  c(21) Steroidal Glycosides  
Four new podocarpane-type trinorditerpenes from Aleurites moluccana 期刊论文
HELVETICA CHIMICA ACTA, 2007, 卷号: 90, 期号: 10, 页码: 2017-2023
Authors:  Liu, Hai-Yang;  Li, Shi-Jin;  Zhao, Yi;  Ni, Wei;  Hao, Xiao-Jiang;  Li, Jun-Zhu;  Hua, Yan;  Xie, Bai-Bo;  Qing, Chen;  Chen, Chang-Xiang
Adobe PDF(193Kb)  |  Favorite  |  View/Download:235/91  |  Submit date:2011/11/24
Azadirachta-indica  Taiwania-cryptomerioides  Stem Bark  Tricyclic Diterpenoids  Constituents  Assay