Taberdines L and M, two new alkaloids from Tabernaemontana divaricata

doi:10.1080/14786419.2021.2015596

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	Taberdines L and M, two new alkaloids from Tabernaemontana divaricata
	Han,Lingling ; Huang,Kepu ; Chen,Chen ; Zhu,Wentao ; Ma,Yehan ; Hao,Xiaojiang; He,Hongping ; Zhang,Yu
	2021
发表期刊	NATURAL PRODUCT RESEARCH
ISSN	1478-6419
摘要	Two new alkaloids, taberdines L (1) and M (2), together with six known alkaloids, were isolated from the twigs and leaves of Tabernaemontana divaricata. Taberdine L (1) represents the first optically active natural member of the allo iboga class of alkaloids with the ethyl side chain in a bridgehead position. Their structures including absolute configuration were elucidated by a combination of MS, NMR, and ECD calculation. The in vitro cytotoxic activities of 1 and 2 against five human cancer cell lines were also evaluated.
关键词	Apocynaceae Tabernaemontana divaricata monoterpenoid indole alkaloids taberdine L taberdine M INDOLE ALKALOIDS BISINDOLE ALKALOIDS ASPIDOSPERMA-TYPE A-I RESISTANCE EXTRACTION IBOGA
DOI	10.1080/14786419.2021.2015596
WOS记录号	WOS:000734241700001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/73047
专题	中国科学院昆明植物研究所
作者单位	1.Yunnan Univ Chinese Med, Sch Chinese Mat Medica, Kunming, Yunnan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochemistry & Plant Resources We, Kunming, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Han,Lingling,Huang,Kepu,Chen,Chen,et al. Taberdines L and M, two new alkaloids from Tabernaemontana divaricata[J]. NATURAL PRODUCT RESEARCH,2021.
APA	Han,Lingling.,Huang,Kepu.,Chen,Chen.,Zhu,Wentao.,Ma,Yehan.,...&Zhang,Yu.(2021).Taberdines L and M, two new alkaloids from Tabernaemontana divaricata.NATURAL PRODUCT RESEARCH.
MLA	Han,Lingling,et al."Taberdines L and M, two new alkaloids from Tabernaemontana divaricata".NATURAL PRODUCT RESEARCH (2021).