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Anthraquinones from the Aerial Parts of Rubia cordifolia with Their NO Inhibitory and Antibacterial Activities 期刊论文
MOLECULES, 2022, 卷号: 27, 期号: 5, 页码: 12
作者:  Luo, Han;  Qin, Wei;  Zhang, Hong;  Ren, Fu-Cai;  Fang, Wen-Tao;  Kong, Qing-Hua;  Yang, Liu;  Zhang, Jian-Mei;  Fang, Cheng-Wu;  Hu, Jiang-Miao;  Liu, Shou-Jin
收藏  |  浏览/下载：233/0  |  提交时间：2022/07/15
Rubia cordifolia  anthraquinones  NO inhibitory activity  antibacterial  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：164/28  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：180/37  |  提交时间：2020/03/26
Canescones A-E: aromatic polyketide dimers with PTP1B inhibitory activity from Penicillium canescens 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 18, 页码: 3274-3281
作者:  Zang, Yi;  Gong, Yi-Hua;  Li, Xu-Wen;  Li, Xiao-Nian;  Liu, Jun-Jun;  Chen, Chun-Mei;  Zhou, Yuan;  Gu, Liang-Hu;  Luo, Zeng-Wei;  Wang, Jian-Ping;  Sun, Wei-Guang;  Zhu, Hu-Cheng;  Zhang, Yong-Hui
浏览  |  Adobe PDF(2538Kb)  |  收藏  |  浏览/下载：176/44  |  提交时间：2019/10/28
Total Synthesis of (+/-)-Cochlearol A 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 17, 页码: 6761-6764
作者:  Zhang, Da-Wei;  Xu, Wen-Dan;  Fan, Hui-Lan;  Liu, Hao-Miao;  Chen, Dong;  Liu, Dan-Dan;  Qin, Hong-Bo
浏览  |  Adobe PDF(999Kb)  |  收藏  |  浏览/下载：150/33  |  提交时间：2019/10/28
Ensemble docking-based virtual screening toward identifying inhibitors against Wee1 kinase 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 15, 页码: 1889-1906
作者:  Li, Yaping;  Wu, Dong-mei;  Kong, Ling-mei;  Zhang, Shuqun;  Du, Haibo;  Sun, Wei;  Zhang, Li;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载：115/0  |  提交时间：2020/03/26
bioassay  ensemble docking  scoring function  virtual screening  Wee1 inhibitors  
Petchiether A attenuates obstructive nephropathy by suppressing TGF-ss/Smad3 and NF-kappa B signalling 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 8, 页码: 5576-5587
作者:  You, Yong-Ke;  Luo, Qi;  Wu, Wei-Feng;  Zhang, Jiao-Jiao;  Zhu, Hong-Jian;  Lao, Lixing;  Lan, Hui Y.;  Chen, Hai-Yong;  Cheng, Yong-Xian
浏览  |  Adobe PDF(3491Kb)  |  收藏  |  浏览/下载：147/47  |  提交时间：2019/10/14
fibrosis  NF-kappa B  obstructive nephropathy  petchiether A  TGF-ss/Smad3  
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：203/68  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Toonamicrocarpavarin, a new tirucallane-type triterpenoid from Toona Ciliata 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 页码: 6
作者:  Zhang, Ling;  Xia, Jianjun;  Duan, Yanqing;  Wei, Keyi;  Gao, Rui;  Li, Dasan;  Liu, Xiaomin;  Zhang, Tiandong;  Qiu, Minghua
浏览  |  Adobe PDF(841Kb)  |  收藏  |  浏览/下载：149/55  |  提交时间：2019/09/10
Toona ciliata  toonamicrocarpavarin  triterpenoid  cytotoxic activity  
Emeriones A-C: Three Highly Methylated Polyketides with Bicyclo[4.2.0]octene and 3,6-Dioxabicyclo[3.1.0]hexane Functionalities from Emericella nidulans 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 13, 页码: 5091-5095
作者:  Li, Qin;  Chen, Chunmei;  He, Yan;  Guan, Danyingzi;  Cheng, Li;  Hao, Xincai;  Wei, Mengsha;  Zheng, Yinyu;  Liu, Chang;  Li, Xiao-Nian;  Zhou, Qun;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1220Kb)  |  收藏  |  浏览/下载：146/17  |  提交时间：2019/08/19