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Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 7, 页码: 1541-1545
作者:  Chen,Yan-Ni;  Ding,Xiao;  Li,Dong-Mei;  Sun,Mao;  Yang,Lei;  Zhang,Yu;  Di,Ying-Tong;  Fang,Xin;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(1835Kb)  |  收藏  |  浏览/下载：80/16  |  提交时间：2022/04/02
Perforatactones D and E, two new C-20 quassinoids with potential activity to induce lysosomal biogenesis from the twigs of Harrisonia perforata (Blanco) Merr. 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 44, 页码: 9637-9640
作者:  Liu,Shuai;  Zhang,Cui-Shan;  Ran,Xiao-Qian;  Tang,Xiao-Han;  Guo,Ya-Rong;  Yan,Ying;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rong-Can;  Di,Ying-Tong
浏览  |  Adobe PDF(997Kb)  |  收藏  |  浏览/下载：92/30  |  提交时间：2022/04/02
PROMISING BIOLOGICAL-ACTIVITY  LIMONOIDS  CHROMONES  FRUITS  DRUG  
Hypermonones A-I, New Polyprenylated Acylphloroglucinols from Hypericum monogynum with Multidrug Resistance Reversal Activity 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 9, 页码: 2422-2432
作者:  Zeng,Yan-Rong;  Li,Ya-Nan;  Yang,Jue;  Yi,Ping;  Huang,Lei;  Huang,Lie-Jun;  Gu,Wei;  Hu,Zhan-Xing;  Li,Yan-Mei;  Yuan,Chun-Mao;  Hao,Xiao-Jiang
浏览  |  Adobe PDF(2840Kb)  |  收藏  |  浏览/下载：71/21  |  提交时间：2022/04/02
Hypericum monogynum  Phytochemistry  Structure elucidation  Biological activity  Multidrug resistance reversal activity  P-GLYCOPROTEIN  MODULATORS  CANCER  
Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway 期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
作者:  Yang,Hao-Jie;  Li,Ya-Nan;  Yan,Chen;  Yang,Jue;  Zeng,Yan-Rong;  Yi,Ping;  Li,Yan-Mei;  Hao,Xiao-Jiang;  Yuan,Chun-Mao
浏览  |  Adobe PDF(2804Kb)  |  收藏  |  浏览/下载：74/20  |  提交时间：2022/04/02
Dysoxylum gotadhora  Rocaglaol derivatives  HCT116  Cytotoxic activity  MAPK pathway  FLAVAGLINES  
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 卷号: 17, 期号: 11, 页码: 2703-2717
作者:  Wei,Ruiran;  Zhao,Yueqin;  Wang,Juan;  Yang,Xu;  Li,Shunlin;  Wang,Yinyuan;  Yang,Xingzhi;  Fei,Jimin;  Hao,Xiaojiang;  Zhao,Yuhan;  Gui,Liming;  Ding,Xiao
浏览  |  Adobe PDF(9123Kb)  |  收藏  |  浏览/下载：82/12  |  提交时间：2022/04/02
Ferroptosis  Tagitinin c  Ros  Er Stress  Nrf2-ho-1 Pathway  Endoplasmic-reticulum Stress  Er-stress  Oxidative Stress  Tumor-suppressor  Nrf2  Death  Iron  Differentiation  Mechanisms  Resistance  
Natural product sciences: an integrative approach to the innovations of plant natural products 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2020
作者:  Shen, Yuemao;  Hao, Xiaojiang
浏览  |  Adobe PDF(4992Kb)  |  收藏  |  浏览/下载：96/14  |  提交时间：2021/01/05
Diterpenes with potential treatment of vitiligo from the aerials parts of Euphorbia antiquorum L 期刊论文
FITOTERAPIA, 2020
作者:  Yuan, Wen-Juan;  Gao, Wen-Fen;  Zhao, Jiang-Yu;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Di, Ying-Tong;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(522Kb)  |  收藏  |  浏览/下载：149/66  |  提交时间：2021/01/05
A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 页码: 9
作者:  Adelakun, Tiwalade A.;  Ding, Xiao;  Ombati, Rose M.;  Zhao, Ning-Dong;  Obodozie-Ofoegbu, Obiageri;  Di, Ying-Tong;  Zhang, Yu;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1037Kb)  |  收藏  |  浏览/下载：282/139  |  提交时间：2019/07/29
Euphorbia fischeriana Steud  highly oxygenated abietanes  phorbol esters  lysosomal biogenesis  
Design, synthesis, and cytotoxic activities of novel hybrids of parthenolide and thiazolidinedione via click chemistry 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 页码: 9
作者:  Qiu, Jie;  Yuan, Chun-Mao;  Wen, Min;  Li, Ya-Nan;  Chen, Juan;  Jian, Jun-You;  Huang, Lie-Jun;  Gu, Wei;  Li, Yan-Mei;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1093Kb)  |  收藏  |  浏览/下载：195/47  |  提交时间：2019/07/29
Parthenolide-thiazolidinedione hybrids  click chemistry  cytotoxic activities  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：306/37  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)