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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：283/62  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
浏览  |  Adobe PDF(13632Kb)  |  收藏  |  浏览/下载：273/33  |  提交时间：2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Natural products against hematological malignancies and identification of their targets 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 12, 页码: 1191-1201
作者:  Xu Ying;  Liu JinBao;  Wu YingLi;  Guo QingLong;  Sun HanDong;  Chen GuoQiang
Adobe PDF(756Kb)  |  收藏  |  浏览/下载：176/29  |  提交时间：2016/05/04
Natural Products  Adenanthin  Hematological Malignancies  Target Identification  
A Group of ent-Kaurane Diterpenoids Inhibit Hedgehog Signaling and Induce Cilia Elongation 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 10
作者:  Jiang,Shiyou;  Du,Jiacheng;  Kong,Qinghua;  Li,Chaocui;  Li,Yan;  Sun,Handong;  Pu,Jianxin;  Mao,Bingyu
浏览  |  Adobe PDF(7288Kb)  |  收藏  |  浏览/下载：187/51  |  提交时间：2016/01/19
Triterpenoids from the Schisandraceae family: an update 期刊论文
NATURAL PRODUCT REPORTS, 2015, 卷号: 32, 期号: 3, 页码: 367-410
作者:  Shi, Yi-Ming;  Xiao, Wei-Lie;  Pu, Jian-Xin;  Sun, Han-Dong;  Sun,HD (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  hdsun@mail.kib.ac.cn
浏览  |  Adobe PDF(3266Kb)  |  收藏  |  浏览/下载：262/82  |  提交时间：2015/06/29
Adenanthin targets proteins involved in the regulation of disulphide bonds 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2014, 卷号: 89, 期号: 2, 页码: 210-216
作者:  Muchowicz, Angelika;  Firczuk, Malgorzata;  Chlebowska, Justyna;  Nowis, Dominika;  Stachura, Joanna;  Barankiewicz, Joanna;  Trzeciecka, Anna;  Klossowski, Szymon;  Ostaszewski, Ryszard;  Zagozdzon, Radoslaw;  Pu, Jian-Xin;  Sun, Han-Dong;  Golab, Jakub
Adobe PDF(1121Kb)  |  收藏  |  浏览/下载：454/56  |  提交时间：2014/06/23
Adenanthin  Cancer  Peroxiredoxin  Protein Disulphide Isomerase  Thioredoxin  
Effect of nigranoic acid on Ca2+ influx and its downstream signal mechanism in NGF-differentiated PC12 cells 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2014, 卷号: 153, 期号: 3, 页码: 725-731
作者:  Yuan, Xiao-Xi;  Yang, Li-Ping;  Yang, Zhong-Lin;  Xiao, Wei-Lie;  Sun, Han-Dong;  Wu, Gui-Sheng;  Luo, Huai-Rong;  Xiao,WL (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  xwl@mail.kib.ac.cn;  luohuairong@mail.kib.ac.cn
Adobe PDF(1628Kb)  |  收藏  |  浏览/下载：451/64  |  提交时间：2014/07/28
Nigranoic Acid  Ca2++  Schisandra Sphaerandra  Bdnf  C-fos  No  
Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2013, 卷号: 11, 期号: 1, 页码: 200
作者:  Zou, Qing-Feng;  Du, Ji-Ke;  Zhang, Hua;  Wang, Hong-Bo;  Hu, Ze-Dong;  Chen, Shu-Peng;  Du, Yong;  Li, Man-Zhi;  Xie, Dan;  Zou, Juan;  Sun, Han-Dong;  Pu, Jian-Xin;  Zeng, Mu-Sheng
浏览  |  Adobe PDF(3788Kb)  |  收藏  |  浏览/下载：276/39  |  提交时间：2013/10/16
Longikaurin a (Lk-a)  Apoptosis  Caspase  Nasopharyngeal Carcinoma  
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 262, 期号: 1, 页码: 80-90
作者:  Li, Lin;  Yue, Grace G. L.;  Lau, Clara B. S.;  Sun, Handong;  Fung, Kwok Pui;  Leung, Ping Chung;  Han, Quanbin;  Leung, Po Sing
Adobe PDF(2066Kb)  |  收藏  |  浏览/下载：264/60  |  提交时间：2014/04/02
Eriocalyxin b  Pancreatic Cancer  Apoptosis  Cell Cycle Arrest  P53  
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells 期刊论文
NATURE CHEMICAL BIOLOGY, 2012, 卷号: 8, 期号: 5, 页码: 486-493
作者:  Liu, Chuan-Xu;  Yin, Qian-Qian;  Zhou, Hu-Chen;  Wu, Ying-Li;  Pu, Jian-Xin;  Xia, Li;  Liu, Wei;  Huang, Xin;  Jiang, Tao;  Wu, Ming-Xuan;  He, Li-Cai;  Zhao, Ya-Xue;  Wang, Xiao-Lin;  Xiao, Wei-Lie;  Chen, Hong-Zhuan;  Zhao, Qian;  Zhou, Ai-Wu;  Wang, Li-Shun;  Sun, Han-Dong;  Chen, Guo-Qiang
Adobe PDF(1434Kb)  |  收藏  |  浏览/下载：658/197  |  提交时间：2012/06/07
Cimicifuga Foetida  Cycloartane  Cytotoxicity  Ranunculaceae  Breast-cancer Cells  Crude Drug Shoma  Racemosa Extract  Simplex Wormsk  Cyclolanostanol Xylosides  Triterpene Glycosides  Chemical-constituents  Prostate-cancer  Aerial Parts  Black Cohosh