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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
作者:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  收藏  |  浏览/下载：244/1  |  提交时间：2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
Effects of a new advanced glycation inhibitor, LR-90, on mitigating arterial stiffening and improving arterial elasticity and compliance in a diabetic rat model: aortic impedance analysis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-33
作者:  S, Satheesan;  J L, Figarola;  T, Dabbs;  S, Rahbar;  R, Ermel
Adobe PDF(967Kb)  |  收藏  |  浏览/下载：216/1  |  提交时间：2017/07/24
Resveratrol Decrease Fructose-Induced Oxidative Stress Mediated by NADPH Oxidase via an AMPK-Dependent Mechanism1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
作者:  Pei-Wen Cheng, PhD;  Wen-Yu Ho, MD, PhD;  Yu-Ting Su, MS;  Pei-Jung Lu,PhD;  Bo-Zone Chen MS;  Wen-Han Cheng, MS;  Wen-Hsien Lu, MD, MS;  Gwo-Ching Sun, MD;  Tung-Chen Yeh, MD;  Michael Hsiao DVM, PhD;  Ching-Jiunn Tseng, MD, PhD
Adobe PDF(1555Kb)  |  收藏  |  浏览/下载：103/1  |  提交时间：2017/07/24
Ampk  Hypertension  Nucleus Tractus Solitarii  Nitrogen Oxides  Resveratrol  
Lipid Disorders in NAFLD and Chronic Kidney Disease 期刊论文
BIOMEDICINES, 2021, 卷号: 9, 期号: 10, 页码: 1405
作者:  Yang,Meng;  Geng,Chang-An;  Liu,Xinguang;  Guan,Min
收藏  |  浏览/下载：42/0  |  提交时间：2022/04/02
lipid  NAFLD  chronic kidney disease  NONALCOHOLIC FATTY LIVER  ENDOPLASMIC-RETICULUM STRESS  MESENCHYMAL STEM-CELLS  INSULIN-RESISTANCE  LIPOPROTEIN METABOLISM  OBETICHOLIC ACID  RENAL-FIBROSIS  RECEPTOR-ALPHA  MOUSE MODEL  ER STRESS  
Bitter Melon and Diabetes Mellitus 期刊论文
FOOD REVIEWS INTERNATIONAL, 2021
作者:  Gao,Ya;  Li,Xian;  Huang,Yanjie;  Chen,Jianchao;  Qiu,Minghua
收藏  |  浏览/下载：44/0  |  提交时间：2022/04/02
Bitter melon  diabetes mellitus  crude extracts  phyto-metabolites  hypoglycemic mechanism  MOMORDICA-CHARANTIA L.  11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1  ALPHA-GLUCOSIDASE INHIBITION  INSULIN-RESISTANCE  ANTIDIABETIC ACTIVITIES  GUT MICROBIOTA  STRUCTURAL-CHARACTERIZATION  PHENOLIC-COMPOUNDS  OXIDATIVE STRESS  PROTEIN-KINASE  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
浏览  |  Adobe PDF(2762Kb)  |  收藏  |  浏览/下载：105/49  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
Antimicrobial Peptide Brevivin-1RL1 from Frog Skin Secretion Induces Apoptosis and Necrosis of Tumor Cells 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 7, 页码: 2059
作者:  Ju,Xiaoman;  Fan,Dongmei;  Kong,Lingmei;  Yang,Qihong;  Zhu,Yiying;  Zhang,Shaohua;  Su,Guifeng;  Li,Yan
浏览  |  Adobe PDF(3074Kb)  |  收藏  |  浏览/下载：122/44  |  提交时间：2022/04/02
antimicrobial peptide  Brevivin-1RL1  apoptosis  necrosis  caspase  anticancer  BULLFROG  PHOSPHATIDYLSERINE  MECHANISMS  ANTITUMOR  SURFACE  
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
作者:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(2388Kb)  |  收藏  |  浏览/下载：41/6  |  提交时间：2022/04/02
Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(5184Kb)  |  收藏  |  浏览/下载：66/23  |  提交时间：2022/04/02
Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(2223Kb)  |  收藏  |  浏览/下载：101/51  |  提交时间：2022/04/02
Alpinia katsumadai  Katsumadainols A(1)-A(16)  PTP1B/TCPTP selective inhibitors  alpha-glucosidase inhibitors  Antidiabetic effects  THEORETICAL CALCULATION  ABSOLUTE-CONFIGURATION  SEEDS  BLEPHAROCALYXINS  ADDUCT  MOIETY