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Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft' 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105314
作者:  Chen,Jing;  Yu,Yang;  Wu,Jing;  Bao,Mei-Fen;  Kongkiatpaiboon,Sumet;  Schinnerl,Johann;  Cai,Xiang-Hai
收藏  |  浏览/下载：52/0  |  提交时间：2022/04/02
Tabernaemontana divaricata 'Dwaft'  Monoterpenoid indole alkaloid  Aspidosperma-type trimmers  Aspidosperma-type dimers  Cytotoxicity  MONOTERPENOID INDOLE ALKALOIDS  BISINDOLE ALKALOIDS  DIVERSE SKELETONS  A-I  CONOPHYLLINE  
Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft' 期刊论文
BIOORGANIC CHEMISTRY, 2021
作者:  Chen,Jing;  Yu,Yang;  Wu,Jing;  Bao,Mei-Fen;  Kongkiatpaiboon,Sumet;  Schinnerl,Johann;  Cai,Xiang-Hai
Adobe PDF(1373Kb)  |  收藏  |  浏览/下载：110/32  |  提交时间：2023/09/08
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
作者:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
Adobe PDF(523Kb)  |  收藏  |  浏览/下载：67/17  |  提交时间：2022/04/02
Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID  
Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104767
作者:  Guo,Sheng;  Xie,Hang;  Lei,Yu;  Liu,Bin;  Zhang,Li;  Xu,Yechun;  Zuo,Zhili
浏览  |  Adobe PDF(3181Kb)  |  收藏  |  浏览/下载：74/28  |  提交时间：2022/04/02
SARS-CoV-2  Main protease  Virtual screening  Biochemical evaluation  
Non-volatile acylphloroglucinol components from Eucalyptus robusta inhibit Zika virus by impairing RdRp activity of NS5 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105303
作者:  Yao,Zhai-Wen;  Liu,Hui;  Zhou,Rui;  Feng,Mi-Yan;  Wang,Fang;  Qin,Xu-Jie;  Chen,Xiu-Xiu;  Zheng,Chang-Bo;  Luo,Rong-Hua;  Yang,Liu-Meng;  Cen,Shan;  Xiong,Si-Dong;  Liu,Hai-Yang;  Zheng,Yong-Tang
浏览  |  Adobe PDF(2139Kb)  |  收藏  |  浏览/下载：69/20  |  提交时间：2022/04/02
Eucalyptus robusta  Acylphloroglucinol dimer  Eucalyprobusone G  Anti-ZIKV agent  NS5 RdRp  INFECTION  BINDING  GROWTH  
Tsaokopyranols A-M, 2,6-epoxydiarylheptanoids from Amomum tsao-ko and their alpha-glucosidase inhibitory activity 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  He, Xiao-Feng;  Zhang, Xu-Ke;  Geng, Chang-An;  Hu, Jing;  Zhang, Xue-Mei;  Guo, Yuan-Qiang;  Chen, Ji-Jun
Adobe PDF(2442Kb)  |  收藏  |  浏览/下载：91/32  |  提交时间：2021/01/05
Anti-inflammatory evaluation and structure-activity relationships of diterpenoids isolated from Euphorbia hylonoma 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 10
作者:  Wei, Wen-Jun;  Qi, Weiyan;  Gao, Xin-Mei;  Feng, Ke-Na;  Ma, Kai-Liang;  Li, Hang-Ying;  Li, Ya;  Gao, Kun
Adobe PDF(2502Kb)  |  收藏  |  浏览/下载：165/41  |  提交时间：2020/03/18
Euphorbia hylonoma  ent-Isopimarane  ent-Rosane  Anti-inflammatory  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：301/36  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)