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Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
作者:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
浏览  |  Adobe PDF(1542Kb)  |  收藏  |  浏览/下载：263/73  |  提交时间：2020/03/18
delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
Blocking ROR1 enhances the roles of erlotinib in lung adenocarcinoma cell lines 期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 3, 页码: 2977-2984
作者:  Wang, Hui-Li;  Liu, Yan-Chun;  Long, Ming-Peng;  Zheng, Chuan;  Yang, Jia-Hui
浏览  |  Adobe PDF(667Kb)  |  收藏  |  浏览/下载：143/38  |  提交时间：2019/11/07
receptor tyrosine kinase-like orphan receptor 1  lung adenocarcinoma  erlotinib resistance  AKT  mammalian target of rapamycin  small interfering RNA  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：310/37  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Microbe-focused glycan array screening platform 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 6, 页码: 1958-1967
作者:  Geissner, Andreas;  Reinhardt, Anika;  Rademacher, Christoph;  Johannssen, Timo;  Monteiro, Joao;  Lepenies, Bernd;  Thepaut, Michel;  Fieschi, Franck;  Mrazkova, Jana;  Wimmerova, Michaela;  Schuhmacher, Frank;  Goetze, Sebastian;  Gruenstein, Dan;  Guo, Xiaoqiang;  Hahm, Heung Sik;  Kandasamy, Jeyakumar;  Leonori, Daniele;  Martin, Christopher E.;  Parameswarappa, Sharavathi G.;  Pasari, Sandip;  Schlegel, Mark K.;  Tanaka, Hidenori;  Xiao, Guozhi;  Yang, You;  Pereira, Claney L.;  Anish, Chakkumkal;  Seeberger, Peter H.
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glycan arrays  microbial antigens  immune receptors  antiglycan antibodies  bacterial lectins  
Synthesis, structure activity relationship and in vitro anti-influenza virus activity of novel polyphenol-pentacyclic triterpene conjugates 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163, 页码: 560-568
作者:  Li, Haiwei;  Li, Man;  Xu, Renyang;  Wang, Shouxin;  Zhang, Yongmin;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
浏览  |  Adobe PDF(1830Kb)  |  收藏  |  浏览/下载：175/27  |  提交时间：2019/03/25
Influenza virus  Pentacyclic triterpene  Polyphenol  Entry inhibitor  Hemagglutinin  
Leucoflavonine, a new bioactive racemic flavoalkaloid from the leaves of Leucosceptrum canum 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 2, 页码: 442-446
作者:  Feng, Ling;  Zhang, Yu;  Liu, Yan-Chun;  Liu, Yan;  Luo, Shi-Hong;  Huang, Chun-Shuai;  Li, Sheng-Hong
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Leucosceptrum canum  Lamiaceae  Flavoalkaloid  Leucoflavonine  Biological activities  
Genome-wide RAD sequencing data provide unprecedented resolution of the phylogeny of temperate bamboos (Poaceae: Bambusoideae) 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 期号: 1, 页码: 11546
作者:  Wang, Xueqin;  Ye, Xiaying;  Zhao, Lei;  Li, Dezhu;  Guo, Zhenhua;  Zhuang, Huifu
浏览  |  Adobe PDF(1943Kb)  |  收藏  |  浏览/下载：231/37  |  提交时间：2017/10/23
Arundinarieae Poaceae  Population Genomics  Inferring Phylogeny  Thamnocalamus Group  Allies Gramineae  Rpl16 Intron  Gbssi Gene  Evolution  Identification  Framework  
ZC4H2 stabilizes Smads to enhance BMP signalling, which is involved in neural development in Xenopus 期刊论文
OPEN BIOLOGY, 2017, 卷号: 7, 期号: 8, 页码: 170122
作者:  Ma, Pengcheng;  Ren, Biyu;  Yang, Xiangcai;  Sun, Bin;  Liu, Xiaoliang;  Kong, Qinghua;  Li, Chaocui;  Mao, Bingyu
浏览  |  Adobe PDF(1985Kb)  |  收藏  |  浏览/下载：154/36  |  提交时间：2017/10/23
Zc4h2  Smad  Smurf  Bone Morphogenesis Protein Signalling  Neural Development  
The opioid receptor triple agonist DPI-125 produces analgesia with less respiratory depression and reduced abuse liability 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 977-989
作者:  Yi, Shou-pu;  Kong, Qing-hong;  Li, Yu-lei;  Pan, Chen-ling;  Yu, Jie;  Cui, Ben-qiang;  Wang, Ying-fei;  Wang, Guan-lin;  Zhou, Pei-lan;  Wang, Li-li;  Gong, Ze-hui;  Su, Rui-bin;  Shen, Yue-hai;  Yu, Gang;  Chang, Kwen-jen
浏览  |  Adobe PDF(854Kb)  |  收藏  |  浏览/下载：337/65  |  提交时间：2017/08/29
Opioid Receptor  Mixed Agonist  Dpi-125  Analgesia  Respiratory Depression  Addiction  
Neoalbaconol inhibits angiogenesis and tumor growth by suppressing EGFR-mediated VEGF production 期刊论文
MOLECULAR CARCINOGENESIS, 2017, 卷号: 56, 期号: 5, 页码: 1414-1426
作者:  Yu, Xinfang;  Li, Wei;  Deng, Qipan;  You, Shuo;  Liu, Haidan;  Peng, Songling;  Liu, Xiaolan;  Lu, Jingchen;  Luo, Xiangjian;  Yang, Lifang;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Liu, Wenbin;  Wu, Shengqi;  Ding, Zhihui;  Feng, Tao;  Zhou, Jian;  Fan, Jia;  Bode, Ann M.;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
浏览  |  Adobe PDF(6365Kb)  |  收藏  |  浏览/下载：306/101  |  提交时间：2017/06/30
Angiogenesis  Breast Cancer  Egfr  Neoalbaconol  Vegf