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New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1648-1666
作者:  Su,Lihua;  Zhang,Xintian;  Ma,Yunbao;  Geng,Changan;  Huang,Xiaoyan;  Hu,Jing;  Li,Tianze;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xuemei;  Chen,Ji-Jun
浏览  |  Adobe PDF(4074Kb)  |  收藏  |  浏览/下载:86/32  |  提交时间:2022/04/02
Guaianolide dimers  Artematrolides AeR  Artemisia atrovirens  Cytotoxicity  Cell cycle  Apoptosis  FARNESYL-PROTEIN TRANSFERASE  CELL-CYCLE ARREST  HEPATOCELLULAR-CARCINOMA  GUAIANOLIDES  LACTONES  INHIBITORS  ARTEMINOLIDE  APOPTOSIS  ARGYI  HELA  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
浏览  |  Adobe PDF(2762Kb)  |  收藏  |  浏览/下载:117/51  |  提交时间:2022/04/02
Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998
作者:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(2388Kb)  |  收藏  |  浏览/下载:48/6  |  提交时间:2022/04/02
Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.  
The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke;  Guo,Yuan-Qiang;  Zhang,Xue-Mei;  Geng,Chang-An
浏览  |  Adobe PDF(5184Kb)  |  收藏  |  浏览/下载:79/23  |  提交时间:2022/04/02
Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID  
Abietane Diterpenoids with Antioxidative Damage Activity from Rosmarinus officinalis 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
作者:  Chen, Xing-Long;  Luo, Qing-Yi;  Hu, Wei-Yan;  Chen, Ji-Jun;  Zhang, Rong-Ping
浏览  |  Adobe PDF(1537Kb)  |  收藏  |  浏览/下载:107/25  |  提交时间:2021/01/05
ent-Labdane and ent-kaurane diterpenoids from Chelonopsis odontochila with alpha-glucosidase inhibitory activity 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Deng, Zhen-Tao;  Chen, Ji-Jun;  Geng, Chang-An
浏览  |  Adobe PDF(3607Kb)  |  收藏  |  浏览/下载:104/35  |  提交时间:2021/01/05
Chepraecoxins A-G, ent-Kaurane Diterpenoids with alpha-Glucosidase Inhibitory Activities from Chelonopsis praecox 期刊论文
FITOTERAPIA, 2019, 卷号: 132, 页码: 60-67
作者:  Deng, Zhen-Tao;  Geng, Chang-An;  Yang, Tong-Hua;  Xiang, Chun-Lei;  Chen, Ji-Jun
Adobe PDF(1349Kb)  |  收藏  |  浏览/下载:212/46  |  提交时间:2019/03/18
Chelonopsis praecox  chepraecoxins A-G  ent-kaurane diterpenoids  alpha-glucosidase  
The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats 期刊论文
HORMONES AND BEHAVIOR, 2015, 卷号: 69, 期号: 1, 页码: 106-115
作者:  Yu,Dafu;  Zhou,Heng;  Yang,Yuan;  Jiang,Yong;  Wang,Tianchao;  Lv,Liang;  Zhou,Qixin;  Yang,Yuexiong;  Dong,Xuexian;  He,Jianfeng;  Huang,Xiaoyan;  Chen,Jijun;  Wu,Kunhua;  Xu,Lin;  Mao,Rongrong;  Xu,L (reprint author),Chinese Acad Sci,Kunming Inst Zool,Lab Learning & Memory,Kunming 650223,Yunnan,Peoples R China.;  lxu@vip.163.com;  talktomaomao@163.com
Adobe PDF(867Kb)  |  收藏  |  浏览/下载:405/150  |  提交时间:2015/06/29
Hypothyroidism  Hyperthyroidism  Depression  Anxiety  Brain-derived Neurotrophic Factor  
UFLC/MS-IT-TOF guided isolation of anti-HBV active chlorogenic acid analogues from Artemisia capillaris as a traditional Chinese herb for the treatment of hepatitis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2014, 卷号: 156, 期号: 10, 页码: 147-154
作者:  Zhao, Yong;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Chen, Hao;  Cao, Tuan-Wu;  He, Kang;  Wang, Hao;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Chen,JJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab PhytoChem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  chenjj@mail.kib.ac.cn
Adobe PDF(605Kb)  |  收藏  |  浏览/下载:296/87  |  提交时间:2015/01/20
Artemisia Capillaris  Uflc/ms-it-tof  Chlorogenic Acid Analogues  Anti-hbv Activity  
Small-Molecule Inhibitors for the Treatment of Hepatitis B Virus Documented in Patents 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2013, 卷号: 13, 期号: 5, 页码: 749-776
作者:  Geng, Chang-An;  Wang, Li-Jun;  Guo, Rui-Hua;  Chen, Ji-Jun
Adobe PDF(616Kb)  |  收藏  |  浏览/下载:355/132  |  提交时间:2013/06/08
Hepatitis b Virus (Hbv)  Small-molecule Inhibitors  Nucleoside Analogs  Non-nucleosides  Natural Products  Synthesized Compounds  Chemical Modification  Patents