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Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
Adobe PDF(7197Kb)  |  收藏  |  浏览/下载：7/3  |  提交时间：2024/07/30
PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE  
Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020
作者:  Li, Xue;  Kong, Lingmei;  Yang, Qihong;  Duan, Aizhu;  Ju, Xiaoman;  Cai, Bicheng;  Chen, Lin;  An, Tao;  Li, Yan
浏览  |  Adobe PDF(2381Kb)  |  收藏  |  浏览/下载：154/59  |  提交时间：2021/01/05
RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling 期刊论文
DEVELOPMENT, 2020
作者:  Ma, Pengcheng;  An, Tao;  Zhu, Liang;  Zhang, Longlong;  Wang, Huishan;  Ren, Biyu;  Sun, Bin;  Zhou, Xia;  Li, Yan;  Mao, Bingyu
浏览  |  Adobe PDF(1986Kb)  |  收藏  |  浏览/下载：123/36  |  提交时间：2021/01/05
Discovery of isopenicin A, a meroterpenoid as a novel inhibitor of tubulin polymerization 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020
作者:  Chen, Lin;  Fan, Dong-Mei;  Tang, Jian-Wei;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Puno, Pema-Tenzin;  Li, Yan
浏览  |  Adobe PDF(1132Kb)  |  收藏  |  浏览/下载：224/55  |  提交时间：2021/01/05
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
浏览  |  Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：187/39  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
USP7 作为结直肠肿瘤治疗靶点的研究 学位论文
: 中国科学院大学, 2017
作者:  安涛
Adobe PDF(4516Kb)  |  收藏  |  浏览/下载：109/6  |  提交时间：2019/06/14
USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
作者:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
浏览  |  Adobe PDF(3138Kb)  |  收藏  |  浏览/下载：805/150  |  提交时间：2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer  
Star-PAP, a poly(A) polymerase, functions as a tumor suppressor in an orthotopic human breast cancer model 期刊论文
CELL DEATH & DISEASE, 2017, 卷号: 8, 期号: 1, 页码: e2582
作者:  Yu, C.;  Gong, Y.;  Zhou, H.;  Wang, M.;  Kong, L.;  Liu, J.;  An, T.;  Zhu, H.;  Li, Y.
浏览  |  Adobe PDF(3022Kb)  |  收藏  |  浏览/下载：207/47  |  提交时间：2017/04/19
Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 9, 页码: 10203-10214
作者:  Kong, Ling-Mei;  Feng, Tao;  Wang, Yuan-Yuan;  Li, Xing-Yao;  Ye, Zhen-Nan;  An, Tao;  Qing, Chen;  Luo, Xiao-Dong;  Li, Yan
浏览  |  Adobe PDF(7290Kb)  |  收藏  |  浏览/下载：255/56  |  提交时间：2016/08/22
Bisleuconothine a  Inhibitor  Wnt Signaling  Colorectal Cancer Cells