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Hepatic Stellate Celland Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis 期刊论文
ACS NANO, 2023, 卷号: 17, 期号: 23, 页码: 23608-23625
作者:  Niu,Xia;  Meng,Yanan;  Cui,Jinjin;  Li,Rui;  Ding,Xiao;  Niu,Bingyu;  Chang,Ge;  Xu,Ning;  Li,Guiling;  Wang,Yucheng;  Wang,Lulu
浏览  |  Adobe PDF(5563Kb)  |  收藏  |  浏览/下载：20/5  |  提交时间：2024/07/10
liver fibrosis  dihydrotanshinone I  hepaticstellate cells  vitamin A  cyclodextrin  liver microbiome  STRATEGY  THERAPY  TARGET  NANOPARTICLES  PATHWAY  
Atractylodinol prevents pulmonary fibrosis through inhibiting TGF-β receptor 1 recycling by stabilizing vimentin 期刊论文
MOLECULAR THERAPY, 2023, 卷号: 31, 期号: 10, 页码: 3015-3033
作者:  Hao,Mengjiao;  Guan,Zhuoji;  Zhang,Zhikang;  Ai,Haopeng;  Peng,Xing;  Zhou,Huihao;  Xu,Jun;  Gu,Qiong
浏览  |  Adobe PDF(8787Kb)  |  收藏  |  浏览/下载：30/11  |  提交时间：2024/07/25
INTERMEDIATE-FILAMENT PROTEIN  MECHANISMS  PATHWAYS  ADHESION  IDENTIFICATION  SMAD  
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
作者:  Ran,Xiaoqian;  Lu,Qing-Yun;  Li,Ying-Yao;  Pu,Xue-Xue;  Guo,Yarong;  Yuan,Ming-Rui;  Guan,Shi-Peng;  Sun,Mao;  Jiao,Lijin;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang;  Luo,Rongcan
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Euphorbia peplus L  Euphorbiaceae  Ent-abietane diterpenoid  Euphejolkinolide A  Autophagy-lysosomal pathway  ALZHEIMERS-DISEASE  TAU PATHOLOGY  NEURODEGENERATION  DITERPENOIDS  INHIBITION  MECHANISMS  APOPTOSIS  CELASTROL  PROTEIN  SYSTEM  
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
作者:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
浏览  |  Adobe PDF(7197Kb)  |  收藏  |  浏览/下载：25/9  |  提交时间：2024/07/30
PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE  
Polysaccharide-Peptide from Trametes versicolor: The Potential Medicine for Colorectal Cancer Treatment 期刊论文
BIOMEDICINES, 2022, 卷号: 10, 期号: 11, 页码: 2841
作者:  He, Zhicheng;  Lin, Jian;  He, Yingying;  Liu, Shubai
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Trametes versicolor  polysaccharide peptide  colorectal cancer  traditional medicine  PROTEIN-BOUND POLYSACCHARIDE  QUEL PS-K  CORIOLUS-VERSICOLOR  IN-VITRO  ANTICANCER ACTIVITY  SIGNALING PATHWAY  ANTITUMOR  CELLS  MUSHROOM  COMBINATION  
Toxicity and Antiulcer Properties of Ipomoea wightii (Wall.) Choisy Leaves: An In Vivo Approach Using Wistar Albino Rats 期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2022, 卷号: 2022, 页码: 4328571
作者:  Sathyanarayanan, Saikumar;  Sreeja, Puthanpura Sasidharan;  Arunachalam, Karuppusamy;  Parimelazhagan, Thangaraj
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GLUTATHIONE-REDUCTASE  MEDICINAL-PLANTS  METHANOL EXTRACT  GASTRIC-ULCER  GAERTN. ROXB.  ANTIOXIDANT  PALMITOYLETHANOLAMIDE  METABOLISM  LIVER  
Editorial: Oxidative stress related to cellular metabolism in lung health and diseases 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 1015423
作者:  Arunachalam, Karuppusamy;  Anand, Krishnan;  Palanisamy, Subramanian;  Anathy, Vikas
浏览  |  Adobe PDF(526Kb)  |  收藏  |  浏览/下载：20/1  |  提交时间：2024/08/21
reactive oxygen species  oxidative stress  lung disease  respiratory illness  drug toxicity and therapy  OBSTRUCTIVE PULMONARY-DISEASE  PREVALENCE  ASTHMA  
Polysaccharide Peptide Induced Colorectal Cancer Cells Apoptosis by Down-Regulating EGFR and PD-L1 Expression 期刊论文
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2022, 卷号: 21, 期号: 1, 页码: e123909
作者:  Lin Jian;  He Zhicheng;  Liu Shubai
浏览  |  Adobe PDF(3879Kb)  |  收藏  |  浏览/下载：24/2  |  提交时间：2024/08/21
Colorectal Cancer  Trametes Versicolor  EGFR  PD-L1  Polysaccharide Peptide  CORIOLUS-VERSICOLOR  SIGNALING PATHWAY  COLON-CANCER  T-CELLS  STATISTICS  THERAPY  
The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 874474
作者:  Arunachalam, Karuppusamy;  Sreeja, Puthanpura Sasidharan;  Yang, Xuefei
浏览  |  Adobe PDF(2493Kb)  |  收藏  |  浏览/下载：21/7  |  提交时间：2024/08/21
reactive oxygen species  oxidative stress  antioxidant  diabetes mellitus  mushroom polysaccharides  AGARICUS-BLAZEI MURILL  GANODERMA-LUCIDUM POLYSACCHARIDES  ACTIVATED SIGNALING PATHWAYS  TYPE-2 DIABETES-MELLITUS  PROTEIN-KINASE-C  MT-ALPHA-GLUCAN  MEDICINAL MUSHROOM  SUBMERGED-CULTURE  PHELLINUS-LINTEUS  STRUCTURAL-CHARACTERIZATION  
Current Advances in Mechanisms and Treatment of Dry Eye Disease: Toward Anti-inflammatory and Immunomodulatory Therapy and Traditional Chinese Medicine 期刊论文
FRONTIERS IN MEDICINE, 2022, 卷号: 8, 页码: 815075
作者:  Ling, Jiawei;  Chan, Ben Chung-Lap;  Tsang, Miranda Sin-Man;  Gao, Xun;  Leung, Ping Chung;  Lam, Christopher Wai-Kei;  Hu, Jiang-Miao;  Wong, Chun Kwok
浏览  |  Adobe PDF(786Kb)  |  收藏  |  浏览/下载：20/2  |  提交时间：2024/08/21
inflammation  signaling pathways  immunomodulatory therapy  traditional Chinese medicine  dry eye disease  CHRONIC INFLAMMATORY LESIONS  MEIBOMIAN GLAND DYSFUNCTION  OCULAR-SURFACE  OPHTHALMIC SOLUTION  TEAR FILM  SJOGRENS-SYNDROME  ORAL DOXYCYCLINE  MATRIX METALLOPROTEINASES  TOPICAL CORTICOSTEROIDS  CATARACT-SURGERY