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Design, Synthesis, and Evaluation of the COX-2 Inhibitory Activities of New 1,3-Dihydro-2H-indolin-2-one Derivatives 期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 12, 页码: 4668
作者:  Pan,Taohua;  He,Maofei;  Deng,Lulu;  Li,Jiang;  Fan,Yanhua;  Hao,Xiaojiang;  Mu,Shuzhen
浏览  |  Adobe PDF(3057Kb)  |  收藏  |  浏览/下载：20/6  |  提交时间：2024/05/09
oxindoles  alpha,beta-unsaturated ketone  anti-inflammatory  COX-2 inhibitory activity  ANTIINFLAMMATORY ACTIVITY  NATURAL-PRODUCTS  OXINDOLE-DERIVATIVES  NITRIC-OXIDE  POTENT  CYCLOOXYGENASE-2  DISCOVERY  PAIN  LIABILITY  
Tabernaesine J, a Novel Vincamine-Type Indole Alkaloid with 6/5/6/6/6/5/5 Heptacyclic-Ring System Scaffold from Tabernaemontana pachysiphon 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2022, 卷号: 40, 期号: 4, 页码: 475-479
作者:  Yi,Wen-Fang;  Adelakun,Tiwalade A.;  Bai,Xue;  Zhang,Yu;  Hao,Xiao-Jiang
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Natural products  Alkaloids  Structure elucidation  Tabernaemontana pachysiphon  Tabernaesine J  BISINDOLE ALKALOIDS  A-I  ALGORITHM  
Synthesis of nigranoic acid and manwuweizic acid derivatives as HDAC inhibitors and anti-inflammatory agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 109, 页码: 104728
作者:  Ni,Dong-Xuan;  Wang,Qi;  Li,Yi-Ming;  Cui,Yi-Man;  Shen,Tian-Ze;  Li,Xiao-Li;  Sun,Han-Dong;  Zhang,Xing-Jie;  Zhang,Ruihan;  Xiao,Wei-Lie
收藏  |  浏览/下载：58/0  |  提交时间：2022/04/02
Natural products modification  HDAC inhibition  Inflammasome  Triterpenoid  SCHISANDRA-PROPINQUA  TRITERPENOIDS  MECHANISM  INJURY  
Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum 期刊论文
NEW PHYTOLOGIST, 2021, 卷号: 229, 期号: 3, 页码: 1740-1754
作者:  Liu,Yan;  Luo,Shi-Hong;  Hua,Juan;  Li,De-Sen;  Ling,Yi;  Luo,Qian;  Li,Sheng-Hong
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cadinenes  defensive chemicals  Eupatorium adenophorum  sesquiterpenes  sesquiterpene synthase  NATURAL-PRODUCTS  FUNCTIONAL-CHARACTERIZATION  ABSOLUTE STEREOCHEMISTRY  TERPENE SYNTHASES  EXPRESSION  CLONING  EMISSION  LEAVES  GENES  9-OXO-10,11-DEHYDROAGERAPHORONE  
A strategy combining solid-phase extraction, multiple mass defect filtering and molecular networking for rapid structural classification and annotation of natural products: characterization of chemical diversity in Citrus aurantium as a case study 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 卷号: 413, 期号: 11, 页码: 2879-2891
作者:  Wang,Yi-Kun;  Xiao,Xue-Rong;  Zhou,Zi-Meng;  Xiao,Yao;  Zhu,Wei-Feng;  Liu,Hong-Ning;  Li,Fei
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Solid-phase extraction  Multiple mass defect filtering  Molecular networking  Natural products annotation  Structure and substructure classifications  
Diarylheptanoid-flavanone Hybrids as Multiple-target Antidiabetic Agents from Alpinia katsumadai 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 11, 页码: 3051-3063
作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Huang,Xiao-Yan;  Zhang,Xue-Mei;  Guo,Yuan-Qiang;  Geng,Chang-An
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Alpinia katsumadai  Katsumadainols B-1-B-15  Natural products  Structure elucidation  Biological activity  TYROSINE-PHOSPHATASE 1B  GLYCOGEN-PHOSPHORYLASE  ALPHA-GLUCOSIDASE  ABSOLUTE-CONFIGURATION  STRUCTURE ELUCIDATION  DUAL INHIBITION  SEEDS  CONSTITUENT  DERIVATIVES  CHALCONE  
Lepithiohydimerins A-D: Four Pairs of Neuroprotective Thiohydantoin Dimers Bearing a Disulfide Bond from Maca (Lepidium meyenii Walp.) 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 10, 页码: 2738-2744
作者:  Peng,Xing-Rong;  Zhang,Ran-Ran;  Liu,Jun-Hong;  Li,Zhong-Rong;  Zhou,Lin;  Qiu,Ming-Hua
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Lepidium meyenii Walp  Thiohydantoin dimers  Natural products  Structure elucidation  Biological activity  STRUCTURAL ELUCIDATION  DERIVATIVES  ANTIOXIDANT  HYDANTOIN  
Label-free cell phenotypic study of opioid receptors and discovery of novel mu opioid ligands from natural products 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113872
作者:  Hou,Tao;  Xu,Fangfang;  Peng,Xingrong;  Zhou,Han;  Zhang,Xiuli;  Qiu,Minghua;  Wang,Jixia;  Liu,Yanfang;  Liang,Xinmiao
收藏  |  浏览/下载：85/0  |  提交时间：2022/04/02
Opioid receptors  Dynamic mass redistribution  Natural products  Antagonist  Selectivity  IDENTIFICATION  ANTAGONISTS  SUBSTANCES  NALOXEGOL  AGONISTS  SAFETY  MACA  
Bioinspired Network Analysis Enabled Divergent Syntheses and Structure Revision of Pentacyclic Cytochalasans 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 29, 页码: 15963-15971
作者:  Wu,Hai;  Ding,Yiming;  Hu,Kun;  Long,Xianwen;  Qu,Chunlei;  Puno,Pema-Tenzin;  Deng,Jun
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bioinspired network analysis  biomimetic synthesis  natural products  pentacyclic cytochalasans  structure elucidation  DIELS-ALDER REACTION  ISOINDOLONE NUCLEUS  RING-SYSTEM  MEROCYTOCHALASANS  REASSIGNMENT  DESATURATION  GENERATION  ALKALOIDS  CARBONATE  SKELETONS  
Spiro ent-Clerodane Dimers: Discovery and Green Approaches for a Scalable Biomimetic Synthesis 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 15, 页码: 5647-5651
作者:  Li,Xing-Ren;  Yan,Bing-Chao;  Hu,Kun;  He,Shijun;  Sun,Han-Dong;  Zuo,Jianping;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(1474Kb)  |  收藏  |  浏览/下载：81/16  |  提交时间：2022/04/02
DIELS-ALDER REACTIONS  SENSITIZED PHOTOOXYGENATION  NATURAL-PRODUCTS  ACID  DITERPENOIDS