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The inhibitory effect of compound ChlA-F on human bladder cancer cell invasion can be attributed to its blockage of SOX2 protein 期刊论文
CELL DEATH AND DIFFERENTIATION, 2020, 卷号: 27, 期号: 2, 页码: 632-645
作者:  Hua, Xiaohui;  Huang, Maowen;  Deng, Xu;  Xu, Jiheng;  Luo, Yisi;  Xie, Qipeng;  Xu, Jiawei;  Tian, Zhongxian;  Li, Jingxia;  Zhu, Junlan;  Huang, Chao;  Zhao, Qin-shi;  Huang, Haishan;  Huang, Chuanshu
收藏  |  浏览/下载：202/0  |  提交时间：2020/03/24
Magnograndins J-M, elemane sesquiterpenoids from the leaves of Magnolia grandiflora and their inhibitory effects on nitric oxide production 期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 31, 页码: 121-124
作者:  Ding, Lin-Fen;  Liu, Jiang-Xin;  Xie, Zhang-Qiao;  Wang, De-Shen;  Nie, Wei;  Song, Liu-Dong;  Wu, Xing-De;  Zhao, Qin-Shi
浏览  |  Adobe PDF(649Kb)  |  收藏  |  浏览/下载：168/29  |  提交时间：2019/07/29
Magnolia grandiflora  Elemane sesquiterpenoid  Nitric oxide (NO)  
Cytotoxic sesquiterpenoids from the leaves of Magnolia grandiflora 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 155, 页码: 182-190
作者:  Ding, Lin-Fen;  Su, Jia;  Pan, Zheng-Hong;  Zhang, Zhi-Jun;  Li, Xiao-Nian;  Song, Liu-Dong;  Wu, Xing-De;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1049Kb)  |  收藏  |  浏览/下载：586/148  |  提交时间：2018/11/12
Magnolia Grandiflora (Magnoliaceae)  Sesquiterpenoids  Cytotoxic Activity  Nf-kappa b Transcriptional Activity  
Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 66689-66699
作者:  Zhang, Ruowen;  Che, Xun;  Zhang, Jingjie;  Li, Yang;  Li, Jingxia;  Deng, Xu;  Zhu, Junlan;  Jin, Honglei;  Zhao, Qinshi;  Huang, Chuanshu
浏览  |  Adobe PDF(9106Kb)  |  收藏  |  浏览/下载：202/45  |  提交时间：2017/01/05
Chel a  Human Bladder Cancer  Apoptosis  Phlpp2  C-jun  
Natural Product Vibsanin A Induces Differentiation of Myeloid Leukemia Cells through PKC Activation 期刊论文
CANCER RESEARCH, 2016, 卷号: 76, 期号: 9, 页码: 2698-2709
作者:  Yu, Zu-Yin;  Xiao, He;  Wang, Li-Mei;  Shen, Xing;  Jing, Yu;  Wang, Lin;  Sun, Wen-Feng;  Zhang, Yan-Feng;  Cui, Yu;  Shan, Ya-Jun;  Zhou, Wen-Bing;  Xing, Shuang;  Xiong, Guo-Lin;  Liu, Xiao-Lan;  Dong, Bo;  Feng, Jian-Nan;  Wang, Li-Sheng;  Luo, Qing-Liang;  Zhao, Qin-Shi;  Cong, Yu-Wen
浏览  |  Adobe PDF(1368Kb)  |  收藏  |  浏览/下载：289/96  |  提交时间：2016/08/22
Natural product vibsanine A induces differentiation of myeloid leukemia cells through PKC activation 期刊论文
Cancer Research, 2016, 期号: 1, 页码: 1
作者:  Zhao QS(赵勤实)
浏览  |  Adobe PDF(1368Kb)  |  收藏  |  浏览/下载：142/46  |  提交时间：2017/02/28
Vibsanin B Preferentially Targets HSP90b, Inhibits Interstitial Leukocyte Migration, and Ameliorates Experimental Autoimmune Encephalomyelitis 期刊论文
JOURNAL OF IMMUNOLOGY, 2015, 卷号: 194, 期号: 9, 页码: 4489-4497
作者:  Ye, Bai-Xin;  Deng, Xu;  Shao, Li-Dong;  Lu, Ying;  Xiao, Run;  Liu, Yi-Jie;  Jin, Yi;  Xie, Yin-Yin;  Zhao, Yan;  Luo, Liu-Fei;  Ma, Shun;  Gao, Ming;  Zhang, Lian-Ru;  He, Juan;  Zhang, Wei-Na;  Chen, Yi;  Xia, Cheng-Feng;  Deng, Min;  Liu, Ting-Xi;  Zhao, Qin-Shi;  Chen, Sai-Juan;  Chen, Zhu;  Chen,Z (reprint author),Shanghai Jiao Tong Univ,RuiJin Hosp,Sch Med,197 Rui Jin Rd 2,Shanghai 200025,Peoples R China.;  qinshizhao@mail.kib.ac.cn;  sjchen@stn.sh.cn;  zchen@stn.sh.cn
浏览  |  Adobe PDF(1516Kb)  |  收藏  |  浏览/下载：280/44  |  提交时间：2015/07/20
Crucial Role of c-Jun Phosphorylation at Ser63/73 Mediated by PHLPP Protein Degradation in the Cheliensisin A Inhibition of Cell Transformation 期刊论文
CANCER PREVENTION RESEARCH, 2014, 卷号: 7, 期号: 12, 页码: 1270-1281
作者:  Zhu, Junlan;  Zhang, Jingjie;  Huang, Haishan;  Li, Jingxia;  Yu, Yonghui;  Jin, Honglei;  Li, Yang;  Deng, Xu;  Gao, Jimin;  Zhao, Qinshi;  Huang, Chuanshu;  Huang,CS (reprint author),NYU,Sch Med,Nelson Inst Environm Med,57 Old Forge Rd,Tuxedo Pk,NY 10987 USA.
浏览  |  Adobe PDF(3644Kb)  |  收藏  |  浏览/下载：202/38  |  提交时间：2015/01/20
Naturally Occurring Substances  Magnetic-resonance Spectroscopy  Stem-bark  Melodinus-henryi  Conformational-analysis  (+)-scholarisine  Mechanism  Leaves  Seeds  Camptothecin  Indole Alkaloids  Cytotoxicity  Absolute Configuration  Vinca Major  
Sesquiterpenoids from Tussilago farfara and Their Inhibitory Effects on Nitric Oxide Production 期刊论文
PLANTA MEDICA, 2014, 卷号: 80, 期号: 8-9, 页码: 703-709
作者:  Qin, Zhi-Bin;  Zhang, Jing;  Wu, Xing-De;  He, Juan;  Ding, Lin-Fen;  Peng, Li-Yan;  Li, Xing-Yao;  Li, Yan;  Deng, Liang;  Guo, Ya-Dong;  Zhao, Qin-Shi;  Schoch, CL (reprint author), Natl Lib Med, Natl Ctr Biotechnol Informat, NIH, Bethesda, MD 20894 USA.;  schoch2@ncbi.nlm.nih.gov
Adobe PDF(166Kb)  |  收藏  |  浏览/下载：273/83  |  提交时间：2014/10/11
Tussilago Farfara  Asteraceae  Sesquiterpenoid  Nitric Oxide Inhibition  
Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 3, 页码: 841-852
作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Li, Jingxia;  Deng, Xu;  Zhao, Qin-shi;  Huang, Chuanshu
浏览  |  Adobe PDF(3282Kb)  |  收藏  |  浏览/下载：314/65  |  提交时间：2014/05/16
Cheliensisin a  Apoptosis  Colon Cancer  P53  Chemotherapeutic Agent