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Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating [4+2] cycloaddition and target differentiation of enantiomers 期刊论文
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 4
作者:  He, Tao-Bin;  Yan, Bing-Chao;  Zhou, Yuan-Fei;  Sang, Yue-Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Wang, Chu;  Xue, Xiao-Song;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(3322Kb)  |  收藏  |  浏览/下载：10/1  |  提交时间：2024/05/09
DIELS-ALDER REACTION  BIOMIMETIC SYNTHESES  EFFICIENT ACCESS  DEHYDROGENATION  CYCLOHEXANONES  BIOSYNTHESIS  CONVERSION  OXIDATION  DYNAMICS  PHENOLS  
Spiro ent-Clerodane Dimers: Discovery and Green Approaches for a Scalable Biomimetic Synthesis 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 15, 页码: 5647-5651
作者:  Li,Xing-Ren;  Yan,Bing-Chao;  Hu,Kun;  He,Shijun;  Sun,Han-Dong;  Zuo,Jianping;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(1474Kb)  |  收藏  |  浏览/下载：74/16  |  提交时间：2022/04/02
DIELS-ALDER REACTIONS  SENSITIZED PHOTOOXYGENATION  NATURAL-PRODUCTS  ACID  DITERPENOIDS  
(-)-Isoscopariusin A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 23, 页码: 12859-12867
作者:  Yan,Bing-Chao;  Zhou,Min;  Li,Jian;  Li,Xiao-Nian;  He,Shi-Jun;  Zuo,Jian-Ping;  Sun,Han-Dong;  Li,Ang;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(1930Kb)  |  收藏  |  浏览/下载：81/18  |  提交时间：2022/04/02
bioactivity  cyclobutane  natural products  scalable synthesis  structure elucidation  
Elucidation of the Structure of Pseudorubriflordilactone B by Chemical Synthesis 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020
作者:  Yang, Peng;  Li, Jian;  Sun, Li;  Yao, Ming;  Zhang, Xiang;  Xiao, Wei-Lie;  Wang, Jian-Hua;  Tian, Ping;  Sun, Han-Dong;  Puno, Pema-Tenzin;  Li, Ang
浏览  |  Adobe PDF(2437Kb)  |  收藏  |  浏览/下载：173/42  |  提交时间：2021/01/05
Isorugosiformins A-F, six ent-kaurane diterpenoids from Isodon rugosiformis 期刊论文
FITOTERAPIA, 2020
作者:  Zhang, Qin-Yu;  Yan, Bing-Chao;  Hu, Kun;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1626Kb)  |  收藏  |  浏览/下载：125/47  |  提交时间：2021/01/05
Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin 期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 8, 页码: 1122-+
作者:  Zhu, Huifang;  Wang, Bin;  Kong, Lingmei;  An, Tao;  Li, Gentao;  Zhou, Hongyu;  Gong, Liang;  Zhao, Zhangxun;  Gong, Yaxiao;  Sun, Handong;  Puno, Pematenzin;  Li, Yan
浏览  |  Adobe PDF(4600Kb)  |  收藏  |  浏览/下载：184/33  |  提交时间：2019/10/14
Structurally diverse diterpenoids from Isodon ternifolius collected from three regions 期刊论文
TETRAHEDRON, 2019, 卷号: 75, 期号: 19, 页码: 2797-2806
作者:  Gou, Lei-Lei;  Hu, Kun;  Yang, Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Xiang, Chun-Lei;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1097Kb)  |  收藏  |  浏览/下载：233/41  |  提交时间：2019/06/24
Isodon ternifolius  Diterpenoids  Cytotoxic activity  NMR computation  ECD calculation  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：292/64  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Maoeriocalysins A-D, four novel ent-kaurane diterpenoids from Isodon eriocalyx and their structure determination utilizing quantum chemical calculation in conjunction with quantitative interproton distance analysis 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 1, 页码: 45-53
作者:  Yang, Qian;  Hu, Kun;  Yan, Bing-Chao;  Liu, Miao;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1823Kb)  |  收藏  |  浏览/下载：228/32  |  提交时间：2019/03/18
SJP-L-5 inhibits HIV-1 polypurine tract primed plus-strand DNA elongation, indicating viral DNA synthesis initiation at multiple sites under drug pressure 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 期号: 1, 页码: 2574
作者:  Zhang, Xing-Jie;  Wang, Rui-Rui;  Chen, Huan;  Luo, Rong-Hua;  Yang, Liu-Meng;  Liu, Jing-Ping;  Sun, Han-Dong;  Zhang, Hong-Bin;  Xiao, Wei-Lie;  Zheng, Yong-Tang
浏览  |  Adobe PDF(2175Kb)  |  收藏  |  浏览/下载：376/27  |  提交时间：2018/05/08