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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：291/63  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
TEMPORARY REMOVAL: The therapeutic effects of Longikaurin A, a natural ent-kauranoid, in esophageal squamous cell carcinoma depend on ROS accumulation and JNK/p38 MAPK activation (Retraction of Vol 280, Pg 1, 2017) 期刊论文
TOXICOLOGY LETTERS, 2017, 卷号: 280, 页码: 106-106
作者:  Che, Yun;  Wang, Jingnan;  Yuan, Zuyang;  Li, Yuan;  Lu, Zhiliang;  Zhang, Zhirong;  Zhang, Jinyao;  Wan, Jun;  Sun, Handong;  Chen, Zhaoli;  Pu, Jianxin;  He, Jie
收藏  |  浏览/下载：182/0  |  提交时间：2017/12/18
Diterpenoids from Isodon species: an update 期刊论文
NATURAL PRODUCT REPORTS, 2017, 卷号: 34, 期号: 9, 页码: 1090-1140
作者:  Liu, Miao;  Wang, Wei-Guang;  Sun, Han-Dong;  Pu, Jian-Xin
Adobe PDF(10292Kb)  |  收藏  |  浏览/下载：255/29  |  提交时间：2017/10/23
Ent-kaurane Diterpenoids  Japonica Var. Glaucocalyx  Nf-kappa-b  Hepatocellular-carcinoma Cells  C-h Functionalization  Dna-binding Activity  Serra Maxim. Hara  Maoecrystal-v  Abietane Diterpenoids  Chemical-constituents  
Efficient Semisynthesis of (-)-Pseudoirroratin A from (-)-Flexicaulin A and Assessment of Their Antitumor Activities 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 3, 页码: 372-376
作者:  Guo, Lei;  Tsang, Siu Wai;  Zhang, Tong-Xin;  Liu, Kang-Lun;  Guan, Yi-Fu;  Wang, Bo;  Sun, Han-Dong;  Zhang, Hong-Jie;  Wong, Man Shing
Adobe PDF(1840Kb)  |  收藏  |  浏览/下载：219/40  |  提交时间：2017/05/19
(-)-pseudoirroratin a  (-)-flexicaulin a  Apoptosis  Antitumor Activity  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：443/205  |  提交时间：2017/02/28
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
Adobe PDF(13632Kb)  |  收藏  |  浏览/下载：292/33  |  提交时间：2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Targeting peroxiredoxin I potentiates 1,25-dihydroxyvitamin D3-induced cell differentiation in leukemia cells 期刊论文
MOLECULAR MEDICINE REPORTS, 2016, 卷号: 13, 期号: 3, 页码: 2201-2207
作者:  Wei, Wei;  Liu, Chuanxu;  Qin, Dongjun;  Song, Lili;  Xia, Li;  Lei, Hu;  Yu, Yun;  Wang, Weiwei;  Pu, Jianxin;  Sun, Handong;  Wu, Yingli;  Xu, Hanzhang;  Haw, Siguo
浏览  |  Adobe PDF(1039Kb)  |  收藏  |  浏览/下载：193/56  |  提交时间：2016/06/27
Adenanthin  1  25-dihydroxyvitamin D3  Leukemia  Peroxiredoxin i  Cell Differentiation  
Natural products against hematological malignancies and identification of their targets 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 12, 页码: 1191-1201
作者:  Xu Ying;  Liu JinBao;  Wu YingLi;  Guo QingLong;  Sun HanDong;  Chen GuoQiang
Adobe PDF(756Kb)  |  收藏  |  浏览/下载：184/30  |  提交时间：2016/05/04
Natural Products  Adenanthin  Hematological Malignancies  Target Identification  
Triterpenoids from the Schisandraceae family: an update 期刊论文
NATURAL PRODUCT REPORTS, 2015, 卷号: 32, 期号: 3, 页码: 367-410
作者:  Shi, Yi-Ming;  Xiao, Wei-Lie;  Pu, Jian-Xin;  Sun, Han-Dong;  Sun,HD (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  hdsun@mail.kib.ac.cn
Adobe PDF(3266Kb)  |  收藏  |  浏览/下载：269/83  |  提交时间：2015/06/29
Structural Characterization and Antioxidative Activity of Lancifonins: Unique Nortriterpenoids from Schisandra lancifolia 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 5, 页码: 1370-1373
作者:  Shi, Yi-Ming;  Yang, Jie;  Xu, Li;  Li, Xiao-Nian;  Shang, Shan-Zhai;  Cao, Peng;  Xiao, Wei-Lie;  Sun, Han-Dong
Adobe PDF(340Kb)  |  收藏  |  浏览/下载：277/81  |  提交时间：2014/05/16
Lancifodilactone g  Micrandilactone  Cyclization  Chinensis