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Cytotoxic phenolic constituents from Hypericum japonicum 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 33-40
作者:  Zhu, Wei;  Qiu, Jie;  Zeng, Yan-Rong;  Yi, Ping;  Lou, Hua-Yong;  Jian, Jun-You;  Zuo, Ming-Xing;  Duan, Lian;  Gu, Wei;  Huang, Lie-Jun;  Li, Yan-Mei;  Yuan, Chun-Mao;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(902Kb)  |  收藏  |  浏览/下载：421/189  |  提交时间：2019/09/10
Hypericum japonicum thunb. (Hypericaceae)  Phenolic compounds  Xanthone and flavonoid derivatives  Cytotoxic activities  Structure-activity relationship  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：334/43  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
作者:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
浏览  |  Adobe PDF(2055Kb)  |  收藏  |  浏览/下载：282/39  |  提交时间：2019/04/15
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
浏览  |  Adobe PDF(2607Kb)  |  收藏  |  浏览/下载：301/50  |  提交时间：2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Abietane Diterpernoids from the Roots of Euphorbia ebracteolata. 期刊论文
Natural products and bioprospecting, 2018, 卷号: 8, 期号: 2, 页码: 131-135
作者:  Ma, Yuan-Liang;  Tang, Xiao-Han;  Yuan, Wen-Juan;  Ding, Xiao;  Di, Ying-Tong;  Hao, Xiao-Jiang
收藏  |  浏览/下载：83/0  |  提交时间：2019/03/29
Design and synthesis of novel monoterpenoid indole alkaloid-like analogues and their antitumour activities in vitro 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 卷号: 16, 期号: 16, 页码: 3026-3037
作者:  Fang, Jiaqi;  Huang, Tao;  Xia, Mengyuan;  Deng, Lulu;  Hao, Xiaojiang;  Wang, Yuehu;  Mu, Shuzhen
收藏  |  浏览/下载：89/0  |  提交时间：2019/03/29
C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death 期刊论文
PROTEIN & CELL, 2018, 卷号: 9, 期号: 12, 页码: 1013-1026
作者:  Li, Yang;  Zhang, Yu;  Gan, Qiwen;  Xu, Meng;  Ding, Xiao;  Tang, Guihua;  Liang, Jingjing;  Liu, Kai;  Liu, Xuezhao;  Wang, Xin;  Guo, Lingli;  Gao, Zhiyang;  Hao, Xiaojiang;  Yang, Chonglin
收藏  |  浏览/下载：110/0  |  提交时间：2019/03/29
Autocatalytic synthesis of 3-ethyl-3-hydroxy-indole-2-ones and their neuroprotection and antitumor activities' evaluation 期刊论文
COMPTES RENDUS CHIMIE, 2018, 卷号: 21, 期号: 5, 页码: 471-474
作者:  Chen, Gang;  Lin, Jiao;  Zhang, Jie;  Wu, Ya;  Gu, Xuefan;  Hao, Xiaojiang;  Zhang, Yu
收藏  |  浏览/下载：141/0  |  提交时间：2019/03/29
Isatin  3-Ethyl-3-hydroxy-indole-2-one  Antitumor  Neuroprotection  
Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of Bisebracteolasin A 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 1
作者:  Yuan, Wen-Juan;  Ding, Xiao;  Wang, Zhe;  Yang, Bi-Juan;  Li, Xiao-Nian;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Chen, Quan;  Di, Ying-Tong;  Aisa, Haji Akber;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3375Kb)  |  收藏  |  浏览/下载：296/56  |  提交时间：2017/12/18
Meroterpenoids with Antitumor Activities from Guava (Psidium guajava) 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2017, 卷号: 65, 期号: 24, 页码: 4993-4999
作者:  Qin, Xu-Jie;  Yu, Qian;  Yan, Huan;  Khan, Afsar;  Feng, Mi-Yan;  Li, Pan-Pan;  Hao, Xiao-Jiang;  An, Lin-Kun;  Liu, Hai-Yang
浏览  |  Adobe PDF(3439Kb)  |  收藏  |  浏览/下载：298/90  |  提交时间：2017/07/31
Guava  Meroterpenoids  Cytotoxicity  Dna Topoisomerase i Inhibitors  Antiproliferative Activity