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Polysaccharide-Peptide from Trametes versicolor: The Potential Medicine for Colorectal Cancer Treatment 期刊论文
BIOMEDICINES, 2022, 卷号: 10, 期号: 11, 页码: 2841
作者:  He, Zhicheng;  Lin, Jian;  He, Yingying;  Liu, Shubai
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Trametes versicolor  polysaccharide peptide  colorectal cancer  traditional medicine  PROTEIN-BOUND POLYSACCHARIDE  QUEL PS-K  CORIOLUS-VERSICOLOR  IN-VITRO  ANTICANCER ACTIVITY  SIGNALING PATHWAY  ANTITUMOR  CELLS  MUSHROOM  COMBINATION  
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
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4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway 期刊论文
TETRAHEDRON, 2015, 卷号: 71, 期号: 52, 页码: 9673-9678
作者:  Chen, Xiao-Qiang;  Zhao, Si-Meng;  Wang, Zhe;  Zeng, Guang-Zhi;  Huang, Mao-Bo;  Tan, Ning-Hua
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Rubia Cordifolia  Rubicordins A-c  Cyclopeptides  Cytotoxicity  Nf-kappa b Signaling Pathway  
Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNF alpha and ROS production 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 4, 页码: 1995-2008
作者:  Yu, Xinfang;  Deng, Qipan;  Li, Wei;  Xiao, Lanbo;  Luo, Xiangjian;  Liu, Xiaolan;  Yang, Lifang;  Peng, Songling;  Ding, Zhihui;  Feng, Tao;  Zhou, Jian;  Fan, Jia;  Bode, Ann M.;  Dong, Zigang;  Liu, Jikai;  Cao, Ya;  Liu,JK (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Beijing 100864,Yunnan,Peoples R China.;  jkliu@mail.kib.ac.cn;  ycao98@vip.sina.com
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Necoalbaconol  Necroptosis  Ripk  Tnf Alpha  Nf-kappa b Signaling Pathway  Ros  
Adenanthin targets peroxiredoxin I/II to kill hepatocellular carcinoma cells 期刊论文
CELL DEATH & DISEASE, 2014, 卷号: 5, 页码: e1400
作者:  Hou, J-K;  Huang, Y.;  He, W.;  Yan, Z-W;  Fan, L.;  Liu, M-H;  Xiao, W-L;  Sun, H-D;  Chen, G-Q;  Chen,GQ (reprint author),Shandong Jiaotong Univ,Sch Med,Dept Pathophysiol,280 Chong Qing South Rd,Shanghai 200025,Peoples R China.;  huangying@shsmu.edu.cn;  hdsun@mail.kib.ac.cn;  chengq@shsmu.edu.cn
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Reactive Oxygen  Cancer-cells  Signaling Pathway  Mechanisms  Apoptosis  Ros  Roles  Death  Prdx1  
Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 7, 页码: e103760
作者:  Kong, Yanjie;  Chen, Jianchao;  Zhou, Zhongmei;  Xia, Houjun;  Qiu, Ming-Hua;  Chen, Ceshi;  Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming,Yunnan,Peoples R China.;  qiuminghua@mail.kib.ac.cn;  chenc@mail.kiz.ac.cn
Adobe PDF(3184Kb)  |  收藏  |  浏览/下载:207/39  |  提交时间:2014/11/25
Inhibitory-activity  Signaling Pathway  Carcinoma  Growth  Activation  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
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One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.