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Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：189/30  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
作者:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
Adobe PDF(4714Kb)  |  收藏  |  浏览/下载：320/42  |  提交时间：2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Discovery of novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by virtual screening 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78, 页码: 306-316
作者:  Zhou, Yeheng;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Li, Yingying;  Zhang, Li;  Sun, Wei;  Liu, Xingyong;  Zuo, Zhili
Adobe PDF(2732Kb)  |  收藏  |  浏览/下载：251/42  |  提交时间：2019/03/25
IDO1  Molecular docking  HipHop pharmacophore  3D-QSAR  PAINS  
Pharmacophore modeling, molecular docking and molecular dynamics simulations toward identifying lead compounds for Chk1 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 卷号: 76, 页码: 53-60
作者:  Li, Yaping;  Peng, Jiale;  Zhou, Yeheng;  Li, Penghua;  Li, Yingying;  Liu, Xingyong;  Siddique, Abu Nasar;  Zhang, Li;  Zuo, Zhili
收藏  |  浏览/下载：137/0  |  提交时间：2018/11/12
Checkpoint kinase 1 inhibitor  Virtual screening  Pharmacophore modeling  Molecular docking  Molecular dynamics simulations  
苄烯叉苯肽类化合物及其药物组合物和其应用 专利
申请日期: 2018-05-16, 公开日期: 2018-11-06
发明人:  左之利;  孙威;  彭佳乐;  孔德信;  周业珩
收藏  |  浏览/下载：76/0  |  提交时间：2019/08/14
Structure-Activity Relationship of Xanthones as Inhibitors of Xanthine Oxidase 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 2, 页码: 365
作者:  Zhou, Ling-Yun;  Peng, Jia-Le;  Wang, Jun-Ming;  Geng, Yuan-Yuan;  Zuo, Zhi-Li;  Hua, Yan
Adobe PDF(2334Kb)  |  收藏  |  浏览/下载：206/41  |  提交时间：2018/05/08
Xanthone  Xanthine Oxidase Inhibitors  3d-qsar  Gout  
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
Adobe PDF(13632Kb)  |  收藏  |  浏览/下载：291/33  |  提交时间：2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Three Minor Diterpenoids with Three Carbon Skeletons from Euphorbia peplus 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 9, 页码: 2166-2169
作者:  Wan, Luo-Sheng;  Nian, Yin;  Ye, Chen-Jun;  Shao, Li-Dong;  Peng, Xing-Rong;  Geng, Chang-An;  Zuo, Zhi-Li;  Li, Xiao-Nian;  Yang, Jian;  Zhou, Ming;  Qiu, Ming-Hua
Adobe PDF(842Kb)  |  收藏  |  浏览/下载：282/73  |  提交时间：2016/08/22
Lingzhilactones from Ganoderma lingzhi ameliorate adriamycin-induced nephropathy in mice 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2015, 卷号: 176, 页码: 385-393
作者:  Yan, Yong-Ming;  Wang, Xin-Long;  Zhou, Li-Li;  Zhou, Feng-Jiao;  Li, Rong;  Tian, Yuan;  Zuo, Zhi-Li;  Fang, Ping;  Chung, Arthur C. K.;  Hou, Fan-Fan;  Cheng, Yong-Xian
Adobe PDF(8566Kb)  |  收藏  |  浏览/下载：624/64  |  提交时间：2016/02/01
Ganoderma Lingzhi  Ganodermataceae  Meroterpenoids  Chronic Kidney Disease  Reactive Oxygen Species  Nrf2  
Asymmetric synthesis of common aza-tricyclic core of various alkaloids 期刊论文
TETRAHEDRON LETTERS, 2015, 卷号: 56, 期号: 40, 页码: 5460-5464
作者:  Ding,Ming;  Tong,Xiaogang;  Li,Dashan;  Liang,Kangjiang;  Zhou,Ankun;  Zuo,Zhili;  Xia,Chengfeng
Adobe PDF(761Kb)  |  收藏  |  浏览/下载：194/43  |  提交时间：2016/01/19
Alkaloid  Asymmetric  Cyclization  Natural Product  Synthesis