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Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
浏览  |  Adobe PDF(2607Kb)  |  收藏  |  浏览/下载：296/50  |  提交时间：2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
作者:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
收藏  |  浏览/下载：371/0  |  提交时间：2018/11/12
Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization  
Identification of Ingol and Rhamnofolane Diterpenoids from Euphorbia resinifera and Their Abilities to Induce Lysosomal Biosynthesis 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 5, 页码: 1209-1218
作者:  Zhao, Ning-Dong;  Ding, Xiao;  Song, Yu;  Yang, Dong-Qiong;  Adelakun, Tiwalade Adegoke;  Qian, Wen-Dan;  Zhang, Yu;  Di, Ying-Tong;  Gao, Fang;  Hao, Xiao-Jiang;  Li, Shun-Lin
收藏  |  浏览/下载：453/0  |  提交时间：2018/07/16
The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
作者:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
收藏  |  浏览/下载：419/0  |  提交时间：2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
Hypermonins A and B, two 6-norpolyprenylated acylphloroglucinols with unprecedented skeletons from Hypericum monogynum 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 卷号: 16, 期号: 22, 页码: 4195-4198
作者:  Zeng, Yan-Rong;  Yi, Ping;  Gu, Wei;  Xiao, Chun-Xia;  Huang, Lie-Jun;  Tian, Dong-Song;  Yan, Hui;  Chen, Duo-Zhi;  Yuan, Chun-Mao;  Hao, Xiao-Jiang
收藏  |  浏览/下载：97/0  |  提交时间：2019/03/29
Anisucoumaramide, a Bioactive Coumarin from Clausena anisumolens 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 4, 页码: 798-804
作者:  Wang, Yun-Song;  Li, Bi-Tao;  Liu, Shi-Xi;  Wen, Zheng-Qi;  Yang, Jing-Hua;  Zhang, Hong-Bin;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(1274Kb)  |  收藏  |  浏览/下载：232/53  |  提交时间：2017/08/29
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
作者:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(3775Kb)  |  收藏  |  浏览/下载：155/38  |  提交时间：2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling  
Garmultins A-G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 22, 页码: 5904-5907
作者:  Tian, Dong Song;  Yi, Ping;  Xia, Lei;  Xiao, Xin;  Fan, Yi Min;  Gu, Wei;  Huang, Lie Jun;  Ben-David, Yaacov;  Di, Ying Tong;  Yuan, Chun Mao;  Hao, Xiao Jiang
浏览  |  Adobe PDF(1168Kb)  |  收藏  |  浏览/下载：365/73  |  提交时间：2017/01/05
Protein kinase C controls lysosome biogenesis independently of mTORC1 期刊论文
NATURE CELL BIOLOGY, 2016, 卷号: 18, 期号: 10, 页码: 1065-1077
作者:  Li, Yang;  Xu, Meng;  Ding, Xiao;  Yan, Chen;  Song, Zhiqin;  Chen, Lianwan;  Huang, Xiahe;  Wang, Xin;  Jian, Youli;  Tang, Guihua;  Tang, Changyong;  Di, Yingtong;  Mu, Shuzhen;  Liu, Xuezhao;  Liu, Kai;  Li, Ting;  Wang, Yingchun;  Miao, Long;  Guo, Weixiang;  Hao, Xiaojiang;  Yang, Chonglin
浏览  |  Adobe PDF(4637Kb)  |  收藏  |  浏览/下载：571/152  |  提交时间：2016/12/21
Longphyllinesides A and B: natural Diels-Alder adducts from Daphniphyllum longeracemosum? 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 26, 页码: 4017-4021
作者:  Di, Ying-Tong;  Wee, Chorng-Shin;  Li, Chun-Shun;  Kong, Ning-Chuan;  Wang, Jun-Song;  Fang, Xin;  Zhu, Hua-Jie;  Wu, Yun-Dong;  Hao, Xiao-Jiang;  Zhu,HJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China.;  hjzhu@mail.kib.ac.cn;  hydwu@ust.hk;  haoxj@mail.kib.ac.cn
Adobe PDF(1053Kb)  |  收藏  |  浏览/下载：290/45  |  提交时间：2014/07/28
Daphniphyllum Longeracemosum  Alkaloid  Biogenetic Pathway  Chemical Computation  Diels-alderase