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Hypermonins A and B, two 6-norpolyprenylated acylphloroglucinols with unprecedented skeletons from Hypericum monogynum
Zeng, Yan-Rong; Yi, Ping; Gu, Wei; Xiao, Chun-Xia; Huang, Lie-Jun; Tian, Dong-Song; Yan, Hui; Chen, Duo-Zhi; Yuan, Chun-Mao; Hao, Xiao-Jiang
2018
Source PublicationORGANIC & BIOMOLECULAR CHEMISTRY
ISSN1477-0520
Volume16Issue:22Pages:4195-4198
AbstractTwo new 6-norpolycyclic polyprenylated acylphloroglucinols (PPAPs), hypermonins A (1) and B (2), featuring an undescribed decahydroindeno[1,7-bc]furan ring system, were isolated from the leaves and twigs of Hypericum monogynum. These compounds are a pair of epimers with opposite configurations at the C-5 position. Their structures, including their absolute configurations, were determined by extensive spectroscopic analysis and electronic circular dichroism (ECD) calculations. A plausible biosynthetic pathway of 1 and 2 was also proposed. Compound 1 exhibited a significant protective effect against corticosterone-induced injury in PC12 cells.
Indexed BySCI
Language英语
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/64730
Collection中国科学院昆明植物研究所
Recommended Citation
GB/T 7714
Zeng, Yan-Rong,Yi, Ping,Gu, Wei,et al. Hypermonins A and B, two 6-norpolyprenylated acylphloroglucinols with unprecedented skeletons from Hypericum monogynum[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2018,16(22):4195-4198.
APA Zeng, Yan-Rong.,Yi, Ping.,Gu, Wei.,Xiao, Chun-Xia.,Huang, Lie-Jun.,...&Hao, Xiao-Jiang.(2018).Hypermonins A and B, two 6-norpolyprenylated acylphloroglucinols with unprecedented skeletons from Hypericum monogynum.ORGANIC & BIOMOLECULAR CHEMISTRY,16(22),4195-4198.
MLA Zeng, Yan-Rong,et al."Hypermonins A and B, two 6-norpolyprenylated acylphloroglucinols with unprecedented skeletons from Hypericum monogynum".ORGANIC & BIOMOLECULAR CHEMISTRY 16.22(2018):4195-4198.
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