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Development of actein derivatives as potent anti-triple negative breast cancer agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 89, 页码: 129307
作者:  Zhang,Honglin;  Chen,Yiyan;  Huang,Songwen;  Xiao,Wen-Wen;  Qiu,Ming-Hua;  Shao,Li-Dong;  Chen,Chuan-Huizi;  Li,Dashan
浏览  |  Adobe PDF(1187Kb)  |  收藏  |  浏览/下载:0/0  |  提交时间:2024/07/22
Actein  Modification  Triple negative breast cancer  Structure-activity relationships  Mechanism  GROWTH-INHIBITORY ACTIVITY  BLACK COHOSH  EXTRACTS  
Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis 期刊论文
PHYTOMEDICINE, 2020
作者:  Wang Yu-Ling;  Wu Wei;  Su Yong-Nan;  Ai Zhi-Peng;  Mou Han-Chuan;  Wan Luo-Sheng;  Luo Ying;  Qiu Ming-Hua;  Zhang Ji-Hong
浏览  |  Adobe PDF(7972Kb)  |  收藏  |  浏览/下载:146/38  |  提交时间:2021/01/05
Actein Inhibits Tumor Growth and Metastasis in HER2-Positive Breast Tumor Bearing Mice via Suppressing AKT/mTOR and Ras/Raf/MAPK Signaling Pathways 期刊论文
FRONTIERS IN ONCOLOGY, 2020
作者:  Wu, Xiao-Xiao;  Yue, Grace Gar-Lee;  Dong, Jin-Run;  Lam, Christopher Wai-Kei;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
浏览  |  Adobe PDF(1739Kb)  |  收藏  |  浏览/下载:187/77  |  提交时间:2021/01/05
C-28 steroids from the fruiting bodies of Ganoderma resinaceum with potential anti-inflammatory activity 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 168, 页码: 8
作者:  Shi, Qiangqiang;  Huang, Yanjie;  Su, Haiguo;  Gao, Ya;  Peng, Xingrong;  Zhou, Lin;  Li, Xiaonian;  Qiu, Minghua
浏览  |  Adobe PDF(824Kb)  |  收藏  |  浏览/下载:257/77  |  提交时间:2020/03/26
Ganoderma resinaceum boud  Ganodermataceae  Ergostane-type  Steroids  Anti-inflammatory activity  
Three new C23 steroids from the leaves and stems of Nicandra physaloides 期刊论文
STEROIDS, 2019, 卷号: 150, 页码: 4
作者:  Zhang, Ling;  Peng, Xingrong;  Zhao, Gaoting;  Xia, Jianjun;  Lu, Jing;  Zhou, Lin;  Wang, Kunmiao;  Li, Zhihua;  Qiu, Minghua
浏览  |  Adobe PDF(416Kb)  |  收藏  |  浏览/下载:176/53  |  提交时间:2019/10/28
Nicandra physaloides  Solanaceae  Withanolide  C23 steroids  
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
浏览  |  Adobe PDF(3189Kb)  |  收藏  |  浏览/下载:184/37  |  提交时间:2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Actein Inhibits the Proliferation and Adhesion of Human Breast Cancer Cells and Suppresses Migration in vivo 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 1466
作者:  Wu, Xiao-Xiao;  Yue, Grace Gar-Lee;  Dong, Jin-Run;  Lam, Christopher Wai-Kei;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
收藏  |  浏览/下载:87/0  |  提交时间:2019/03/29
Withanolides from aerial parts of Nicandra physalodes 期刊论文
PHYTOCHEMISTRY, 2017, 卷号: 137, 页码: 148-155
作者:  Yu, Mu-Yuan;  Zhao, Gao-Ting;  Liu, Jie-Qing;  Khan, Afsar;  Peng, Xing-Rong;  Zhou, Lin;  Dong, Jin-Run;  Li, Hai-Zhou;  Qiu, Ming-Hua
浏览  |  Adobe PDF(577Kb)  |  收藏  |  浏览/下载:300/45  |  提交时间:2017/06/30
Nicandra Physalodes  Solanaceae  Withanolides  Cytotoxicity  
A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells 期刊论文
ONCOLOGY REPORTS, 2017, 卷号: 37, 期号: 4, 页码: 2079-2086
作者:  Dai, Xiaoli;  Liu, Jing;  Nian, Yin;  Qiu, Ming-Hua;  Luo, Ying;  Zhang, Jihong
浏览  |  Adobe PDF(1057Kb)  |  收藏  |  浏览/下载:231/54  |  提交时间:2017/06/01
Cimicifuga  Apoptosis  Autophagy  Colon Cancer Cells  
Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L. 期刊论文
PHYTOCHEMISTRY LETTERS, 2016, 卷号: 18, 期号: 1, 页码: 105-112
作者:  Zhu, Guo-Lei;  Nian, Yin;  Zhu, Di-Fan;  Wan, Luo-Sheng;  Bao, Ni-Man;  Wang, Wei-Hua;  Zhou, Lin;  Qiu, Ming-Hua
浏览  |  Adobe PDF(1008Kb)  |  收藏  |  浏览/下载:290/100  |  提交时间:2017/02/14
Cimicifuga Foetida L.  Cytotoxicity  9  19-cycloartane Triterpenoids