Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L.
Zhu, Guo-Lei1,2; Nian, Yin1; Zhu, Di-Fan3; Wan, Luo-Sheng1,2; Bao, Ni-Man1,2; Wang, Wei-Hua1,2; Zhou, Lin1; Qiu, Ming-Hua1
2016-12-01
Source PublicationPHYTOCHEMISTRY LETTERS
Volume18Issue:1Pages:105-112
AbstractEight new cycloartane triterpenoids (1-8), along with eight known analogues (9-16), were isolated from the roots of Cimicifuga foetida L. Their structures were elucidated by spectroscopic analysis and acidic hydrolysis. All of the new compounds were evaluated for their in vitro cytotoxicity against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW480), and compound 2 showed inhibitory activities with IC50 values raging from 2.61 to 3.32 mu M. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.
KeywordCimicifuga Foetida L. Cytotoxicity 9 19-cycloartane Triterpenoids
DOI10.1016/j.phytol.2016.06.002
Indexed BySCI
Language英语
WOS Research AreaPlant Sciences ; Oncology
WOS SubjectPlant Sciences ; Oncology
WOS IDWOS:000389521800021
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Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/33781
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
3.Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kuming 650500, Peoples R China
Recommended Citation
GB/T 7714
Zhu, Guo-Lei,Nian, Yin,Zhu, Di-Fan,et al. Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L.[J]. PHYTOCHEMISTRY LETTERS,2016,18(1):105-112.
APA Zhu, Guo-Lei.,Nian, Yin.,Zhu, Di-Fan.,Wan, Luo-Sheng.,Bao, Ni-Man.,...&Qiu, Ming-Hua.(2016).Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L..PHYTOCHEMISTRY LETTERS,18(1),105-112.
MLA Zhu, Guo-Lei,et al."Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L.".PHYTOCHEMISTRY LETTERS 18.1(2016):105-112.
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