| Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L. | |
Zhu, Guo-Lei1,2; Nian, Yin1 ; Zhu, Di-Fan3; Wan, Luo-Sheng1,2; Bao, Ni-Man1,2; Wang, Wei-Hua1,2; Zhou, Lin1; Qiu, Ming-Hua1
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| 2016-12-01 | |
| 发表期刊 | PHYTOCHEMISTRY LETTERS
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| 卷号 | 18期号:1页码:105-112 |
| 摘要 | Eight new cycloartane triterpenoids (1-8), along with eight known analogues (9-16), were isolated from the roots of Cimicifuga foetida L. Their structures were elucidated by spectroscopic analysis and acidic hydrolysis. All of the new compounds were evaluated for their in vitro cytotoxicity against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW480), and compound 2 showed inhibitory activities with IC50 values raging from 2.61 to 3.32 mu M. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved. |
| 关键词 | Cimicifuga Foetida L. Cytotoxicity 9 19-cycloartane Triterpenoids |
| DOI | 10.1016/j.phytol.2016.06.002 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000389521800021 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/33781 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kuming 650500, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Guo-Lei,Nian, Yin,Zhu, Di-Fan,et al. Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L.[J]. PHYTOCHEMISTRY LETTERS,2016,18(1):105-112. |
| APA | Zhu, Guo-Lei.,Nian, Yin.,Zhu, Di-Fan.,Wan, Luo-Sheng.,Bao, Ni-Man.,...&Qiu, Ming-Hua.(2016).Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L..PHYTOCHEMISTRY LETTERS,18(1),105-112. |
| MLA | Zhu, Guo-Lei,et al."Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L.".PHYTOCHEMISTRY LETTERS 18.1(2016):105-112. |
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| 1-s2.0-S187439001630（1008KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 请求全文 | |
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