| Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L. | |
Zhu, Guo-Lei1,2; Nian, Yin1 ; Zhu, Di-Fan3; Wan, Luo-Sheng1,2; Bao, Ni-Man1,2; Wang, Wei-Hua1,2; Zhou, Lin1; Qiu, Ming-Hua1
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| 2016-12-01 | |
| Source Publication | PHYTOCHEMISTRY LETTERS
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| Volume | 18Issue:1Pages:105-112 |
| Abstract | Eight new cycloartane triterpenoids (1-8), along with eight known analogues (9-16), were isolated from the roots of Cimicifuga foetida L. Their structures were elucidated by spectroscopic analysis and acidic hydrolysis. All of the new compounds were evaluated for their in vitro cytotoxicity against five human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW480), and compound 2 showed inhibitory activities with IC50 values raging from 2.61 to 3.32 mu M. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved. |
| Keyword | Cimicifuga Foetida L. Cytotoxicity 9 19-cycloartane Triterpenoids |
| DOI | 10.1016/j.phytol.2016.06.002 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000389521800021 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/33781 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kuming 650500, Peoples R China |
| Recommended Citation GB/T 7714 | Zhu, Guo-Lei,Nian, Yin,Zhu, Di-Fan,et al. Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L.[J]. PHYTOCHEMISTRY LETTERS,2016,18(1):105-112. |
| APA | Zhu, Guo-Lei.,Nian, Yin.,Zhu, Di-Fan.,Wan, Luo-Sheng.,Bao, Ni-Man.,...&Qiu, Ming-Hua.(2016).Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L..PHYTOCHEMISTRY LETTERS,18(1),105-112. |
| MLA | Zhu, Guo-Lei,et al."Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L.".PHYTOCHEMISTRY LETTERS 18.1(2016):105-112. |
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| 1-s2.0-S187439001630（1008KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
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